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Molecules 2013, 18(12), 15434-15447; doi:10.3390/molecules181215434

G-Quadruplex Guanosine Gels and Single Walled Carbon Nanotubes

1, 2, 2 and 1,*
Received: 7 November 2013 / Revised: 25 November 2013 / Accepted: 3 December 2013 / Published: 11 December 2013
(This article belongs to the Special Issue G-Quadruplexes & i-Motif DNA)
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Solubilization of single walled carbon nanotubes (SWNTs) in aqueous gel phases formed by reversible, G-quadruplex self-assembly of guanosine monophosphate (GMP) alone or with guanosine (Guo) is described. Unlike other media and methods for aqueous solubilization of SWNTs, the guanosine gels (“G-gels”) are found to readily disperse high (>mg/mL) concentrations of individual rather than bundled SWNTs. SWNT dispersions in GMP alone precipitate in several hours and re-form upon shaking; however, dispersions in the binary GMP/Guo gels are indefinitely stable. Increasing GMP or KCl concentration in the binary gels increased the relative abundance of large diameter and semi-conducting SWNTs. Different gel compositions also displayed different selectivities toward SWNTs of different chiralities. These results indicate a strong connection between the self-assembled G-gels and the dimensions and structures of the SWNTs that they solubilize.
Keywords: G-quadruplex; guanosine gel; guanosine tetrad; guanosine monophosphate; single-walled carbon nanotubes G-quadruplex; guanosine gel; guanosine tetrad; guanosine monophosphate; single-walled carbon nanotubes
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Yu, Y.; Pushparaj, V.L.; Nalamasu, O.; McGown, L.B. G-Quadruplex Guanosine Gels and Single Walled Carbon Nanotubes. Molecules 2013, 18, 15434-15447.

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