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Review

Chemistry and Biological Activities of Terpenoids from Copaiba (Copaifera spp.) Oleoresins

by
Lidiam Maia Leandro
1,
Fabiano De Sousa Vargas
1,
Paula Cristina Souza Barbosa
1,
Jamilly Kelly Oliveira Neves
2,
José Alexsandro Da Silva
2 and
Valdir Florêncio Da Veiga-Junior
1,*
1
Chemistry Department, Amazonas Federal University, Av. Gal. Rodrigo Octávio, 6.200, Japiim, Manaus-AM, 69080-900, Brazil
2
Graduate Program on Pharmaceutical Sciences, Paraíba State University, Rua Baraúnas, 351, Bairro Universitário, Campina Grande-PB, 58429-500, Brazil
*
Author to whom correspondence should be addressed.
Molecules 2012, 17(4), 3866-3889; https://doi.org/10.3390/molecules17043866
Submission received: 12 December 2011 / Revised: 18 March 2012 / Accepted: 22 March 2012 / Published: 30 March 2012
(This article belongs to the Special Issue Terpenoids)
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Abstract

Copaiba oleoresins are exuded from the trunks of trees of the Copaifera species (Leguminosae-Caesalpinoideae). This oleoresin is a solution of diterpenoids, especially, mono- and di-acids, solubilized by sesquiterpene hydrocarbons. The sesquiterpenes and diterpenes (labdane, clerodane and kaurane skeletons) are different for each Copaifera species and have been linked to several reported biological activities, ranging from anti-tumoral to embriotoxic effects. This review presents all the substances already described in this oleoresin, together with structures and activities of its main terpenoids.
Keywords: copaiba oil; oleoresin; sesquiterpenes; diterpenes; pharmacological activities copaiba oil; oleoresin; sesquiterpenes; diterpenes; pharmacological activities

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MDPI and ACS Style

Leandro, L.M.; De Sousa Vargas, F.; Barbosa, P.C.S.; Neves, J.K.O.; Da Silva, J.A.; Da Veiga-Junior, V.F. Chemistry and Biological Activities of Terpenoids from Copaiba (Copaifera spp.) Oleoresins. Molecules 2012, 17, 3866-3889. https://doi.org/10.3390/molecules17043866

AMA Style

Leandro LM, De Sousa Vargas F, Barbosa PCS, Neves JKO, Da Silva JA, Da Veiga-Junior VF. Chemistry and Biological Activities of Terpenoids from Copaiba (Copaifera spp.) Oleoresins. Molecules. 2012; 17(4):3866-3889. https://doi.org/10.3390/molecules17043866

Chicago/Turabian Style

Leandro, Lidiam Maia, Fabiano De Sousa Vargas, Paula Cristina Souza Barbosa, Jamilly Kelly Oliveira Neves, José Alexsandro Da Silva, and Valdir Florêncio Da Veiga-Junior. 2012. "Chemistry and Biological Activities of Terpenoids from Copaiba (Copaifera spp.) Oleoresins" Molecules 17, no. 4: 3866-3889. https://doi.org/10.3390/molecules17043866

APA Style

Leandro, L. M., De Sousa Vargas, F., Barbosa, P. C. S., Neves, J. K. O., Da Silva, J. A., & Da Veiga-Junior, V. F. (2012). Chemistry and Biological Activities of Terpenoids from Copaiba (Copaifera spp.) Oleoresins. Molecules, 17(4), 3866-3889. https://doi.org/10.3390/molecules17043866

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