Molecules 2012, 17(4), 3866-3889; doi:10.3390/molecules17043866
Review

Chemistry and Biological Activities of Terpenoids from Copaiba (Copaifera spp.) Oleoresins

Received: 12 December 2011; in revised form: 18 March 2012 / Accepted: 22 March 2012 / Published: 30 March 2012
(This article belongs to the Special Issue Terpenoids)
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: Copaiba oleoresins are exuded from the trunks of trees of the Copaifera species (Leguminosae-Caesalpinoideae). This oleoresin is a solution of diterpenoids, especially, mono- and di-acids, solubilized by sesquiterpene hydrocarbons. The sesquiterpenes and diterpenes (labdane, clerodane and kaurane skeletons) are different for each Copaifera species and have been linked to several reported biological activities, ranging from anti-tumoral to embriotoxic effects. This review presents all the substances already described in this oleoresin, together with structures and activities of its main terpenoids.
Keywords: copaiba oil; oleoresin; sesquiterpenes; diterpenes; pharmacological activities
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MDPI and ACS Style

Leandro, L.M.; de Sousa Vargas, F.; Barbosa, P.C.S.; Neves, J.K.O.; da Silva, J.A.; da Veiga-Junior, V.F. Chemistry and Biological Activities of Terpenoids from Copaiba (Copaifera spp.) Oleoresins. Molecules 2012, 17, 3866-3889.

AMA Style

Leandro LM, de Sousa Vargas F, Barbosa PCS, Neves JKO, da Silva JA, da Veiga-Junior VF. Chemistry and Biological Activities of Terpenoids from Copaiba (Copaifera spp.) Oleoresins. Molecules. 2012; 17(4):3866-3889.

Chicago/Turabian Style

Leandro, Lidiam Maia; de Sousa Vargas, Fabiano; Barbosa, Paula Cristina Souza; Neves, Jamilly Kelly Oliveira; da Silva, José Alexsandro; da Veiga-Junior, Valdir Florêncio. 2012. "Chemistry and Biological Activities of Terpenoids from Copaiba (Copaifera spp.) Oleoresins." Molecules 17, no. 4: 3866-3889.

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