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Molecules 2012, 17(1), 1074-1102; doi:10.3390/molecules17011074
Review

Diversity Oriented Syntheses of Conventional Heterocycles by Smart Multi Component Reactions (MCRs) of the Last Decade

Received: 9 December 2011; in revised form: 11 January 2012 / Accepted: 12 January 2012 / Published: 20 January 2012
(This article belongs to the Special Issue Multicomponent Reaction)
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Abstract: A collection of smart multicomponent reactions (MCRs) with continuative post condensation cyclizations (PCCs) is presented to construct conventional three- to seven-membered heterocyclic compounds in diversity oriented syntheses (DOS). These will provide a high degree of applying economical and ecological advantages as well as of practicability. Water, ionic liquids, and solvent-less syntheses as well as use of various forms of energy as microwave and ultrasonic irradiation are examined and discussed.
Keywords: multicomponent reaction; MCR; MFCR; I-MCR; isocyanide; heterocycle; diversity oriented synthesis; solvent-less synthesis; alternative energy; microwave multicomponent reaction; MCR; MFCR; I-MCR; isocyanide; heterocycle; diversity oriented synthesis; solvent-less synthesis; alternative energy; microwave
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Eckert, H. Diversity Oriented Syntheses of Conventional Heterocycles by Smart Multi Component Reactions (MCRs) of the Last Decade. Molecules 2012, 17, 1074-1102.

AMA Style

Eckert H. Diversity Oriented Syntheses of Conventional Heterocycles by Smart Multi Component Reactions (MCRs) of the Last Decade. Molecules. 2012; 17(1):1074-1102.

Chicago/Turabian Style

Eckert, Heiner. 2012. "Diversity Oriented Syntheses of Conventional Heterocycles by Smart Multi Component Reactions (MCRs) of the Last Decade." Molecules 17, no. 1: 1074-1102.


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