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Molecules 2011, 16(11), 9739-9754; doi:10.3390/molecules16119739
Article

Diversity Oriented Design of Various Benzophenone Derivatives and Their in Vitro Antifungal and Antibacterial Activities

, , , , ,  and *
Received: 3 October 2011 / Revised: 9 November 2011 / Accepted: 14 November 2011 / Published: 23 November 2011
(This article belongs to the Section Medicinal Chemistry)
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Abstract

A series of new substituted benzophenone derivatives was designed, synthesized and screened for their antifungal and antibacterial activities. The bioassays indicated that most of the synthesized compounds showed some antifungal activity against the tested phytopathogenic fungi, but lower antibacterial activities towards the five vibrios isolated from marine sources. The preliminary structure activity relationship (SAR) of the compounds was also discussed.
Keywords: benzophenone derivatives; bioactivity; phytopathogenic fungi; vibrio benzophenone derivatives; bioactivity; phytopathogenic fungi; vibrio
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Sun, L.; Wu, J.; Luo, M.; Wang, X.; Pan, M.; Gou, Z.; Sun, D. Diversity Oriented Design of Various Benzophenone Derivatives and Their in Vitro Antifungal and Antibacterial Activities. Molecules 2011, 16, 9739-9754.

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