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Molecules 2011, 16(11), 9739-9754; doi:10.3390/molecules16119739

Diversity Oriented Design of Various Benzophenone Derivatives and Their in Vitro Antifungal and Antibacterial Activities

Marine College, Shandong University, Weihai Wenhua West Road, No.180, Weihai 264209, China
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Author to whom correspondence should be addressed.
Received: 3 October 2011 / Revised: 9 November 2011 / Accepted: 14 November 2011 / Published: 23 November 2011
(This article belongs to the Section Medicinal Chemistry)
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Abstract

A series of new substituted benzophenone derivatives was designed, synthesized and screened for their antifungal and antibacterial activities. The bioassays indicated that most of the synthesized compounds showed some antifungal activity against the tested phytopathogenic fungi, but lower antibacterial activities towards the five vibrios isolated from marine sources. The preliminary structure activity relationship (SAR) of the compounds was also discussed.
Keywords: benzophenone derivatives; bioactivity; phytopathogenic fungi; vibrio benzophenone derivatives; bioactivity; phytopathogenic fungi; vibrio
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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MDPI and ACS Style

Sun, L.; Wu, J.; Luo, M.; Wang, X.; Pan, M.; Gou, Z.; Sun, D. Diversity Oriented Design of Various Benzophenone Derivatives and Their in Vitro Antifungal and Antibacterial Activities. Molecules 2011, 16, 9739-9754.

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