Molecules 2010, 15(9), 5909-5927; doi:10.3390/molecules15095909
Article

Modular Synthesis of Polyphenolic Benzofurans, and Application in the Total Synthesis of Malibatol A and Shoreaphenol

David Y.-K. Chen* email, Qiang Kang and T. Robert Wu
Chemical Synthesis Laboratory at Biopolis, Institute of Chemical and Engineering Sciences (ICES), Agency for Science, Technology and Research (A*STAR), 11 Biopolis Way, The Helios Block, No. 03-08, 138667, Singapore
* Author to whom correspondence should be addressed.
Received: 29 July 2010; in revised form: 26 August 2010 / Accepted: 27 August 2010 / Published: 27 August 2010
(This article belongs to the Special Issue Diversity Oriented Synthesis)
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Abstract: A modular strategy for the synthesis of hexacyclic dimeric resveratrol polyphenolic benzofurans is reported. The developed synthetic technology was applied to the total synthesis of malibatol A, shoreaphenol, and other biologically relevant poly-phenols.
Keywords: cascade reaction; polyphenol; resveratrol; Friedel-Crafts; natural product; total synthesis

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Cite This Article

MDPI and ACS Style

Chen, D.-K.; Kang, Q.; Wu, T.R. Modular Synthesis of Polyphenolic Benzofurans, and Application in the Total Synthesis of Malibatol A and Shoreaphenol. Molecules 2010, 15, 5909-5927.

AMA Style

Chen D-K, Kang Q, Wu TR. Modular Synthesis of Polyphenolic Benzofurans, and Application in the Total Synthesis of Malibatol A and Shoreaphenol. Molecules. 2010; 15(9):5909-5927.

Chicago/Turabian Style

Chen, David Y.-K.; Kang, Qiang; Wu, T. Robert. 2010. "Modular Synthesis of Polyphenolic Benzofurans, and Application in the Total Synthesis of Malibatol A and Shoreaphenol." Molecules 15, no. 9: 5909-5927.

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