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Molecules 2010, 15(9), 5928-5942; doi:10.3390/molecules15095928
Communication

An Efficient Procedure Based on a MW-Assisted Horner–Wadsworth-Emmons Reaction for the Synthesis of (Z)-3,3-Trisubstituted-a,b-unsaturated Esters

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Received: 28 July 2010; in revised form: 18 August 2010 / Accepted: 25 August 2010 / Published: 27 August 2010
(This article belongs to the Section Organic Synthesis)
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Abstract: A microwave-assisted HWE olefination process of readily accessible aryl-alkyl ketones has been developed to provide a rapid access to (Z)-3,3-trisubstituted-α,β-unsaturated methyl esters, key building blocks for the synthesis of biologically active compounds.
Keywords: (Z)-3,3-trisubstituted α,β-unsaturated methyl esters; aryl-alkyl ketones; Horner–Wadsworth-Emmons reaction; microwave-assisted reactions (Z)-3,3-trisubstituted α,β-unsaturated methyl esters; aryl-alkyl ketones; Horner–Wadsworth-Emmons reaction; microwave-assisted reactions
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Rossi, D.; Baraglia, A.C.; Serra, M.; Azzolina, O.; Collina, S. An Efficient Procedure Based on a MW-Assisted Horner–Wadsworth-Emmons Reaction for the Synthesis of (Z)-3,3-Trisubstituted-a,b-unsaturated Esters. Molecules 2010, 15, 5928-5942.

AMA Style

Rossi D, Baraglia AC, Serra M, Azzolina O, Collina S. An Efficient Procedure Based on a MW-Assisted Horner–Wadsworth-Emmons Reaction for the Synthesis of (Z)-3,3-Trisubstituted-a,b-unsaturated Esters. Molecules. 2010; 15(9):5928-5942.

Chicago/Turabian Style

Rossi, Daniela; Baraglia, Anna Carnevale; Serra, Massimo; Azzolina, Ornella; Collina, Simona. 2010. "An Efficient Procedure Based on a MW-Assisted Horner–Wadsworth-Emmons Reaction for the Synthesis of (Z)-3,3-Trisubstituted-a,b-unsaturated Esters." Molecules 15, no. 9: 5928-5942.


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