Molecules 2010, 15(4), 2667-2685; doi:10.3390/molecules15042667
Review

The Heck Reaction Applied to 1,3- and 1,2-Unsaturated Derivatives, a Way towards Molecular Complexity

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Received: 1 February 2010; in revised form: 26 March 2010 / Accepted: 1 April 2010 / Published: 13 April 2010
(This article belongs to the Special Issue Heck Coupling)
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: This review is an overview of the last ten years’ use of the Mizoroki–Heck coupling applied to 1,2- and 1,3-dienes. Since both these systems form π-allyl palladium intermediates in Pd(0) coupling, they show particular chemical behavior. Many examples of 1,2-dienes Heck reactions are presented. 1,2-Dienes are important substrates because of their high reactivity that makes them useful building blocks for the synthesis of biologically relevant structures.
Keywords: Mizoroki–Heck reaction; palladium; 1,2-dienes; 1,3-dienes
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MDPI and ACS Style

Deagostino, A.; Prandi, C.; Tabasso, S.; Venturello, P. The Heck Reaction Applied to 1,3- and 1,2-Unsaturated Derivatives, a Way towards Molecular Complexity. Molecules 2010, 15, 2667-2685.

AMA Style

Deagostino A, Prandi C, Tabasso S, Venturello P. The Heck Reaction Applied to 1,3- and 1,2-Unsaturated Derivatives, a Way towards Molecular Complexity. Molecules. 2010; 15(4):2667-2685.

Chicago/Turabian Style

Deagostino, Annamaria; Prandi, Cristina; Tabasso, Silvia; Venturello, Paolo. 2010. "The Heck Reaction Applied to 1,3- and 1,2-Unsaturated Derivatives, a Way towards Molecular Complexity." Molecules 15, no. 4: 2667-2685.

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