KeywordsDNA replication; S-phase checkpoint; checkpoint recovery; fork restart; hydroxyurea; ribonucleotide reductase; oxidative stress; cytokinesis arrest; DNA replication checkpoint; cell cycle; DNA replication; DNA topology; DNA topoisomerases; transcription; fork rotation; fork reversal; DNA replication; DDK; Dbf4; Cdc7; MCM; Rad53; cell cycle checkpoint; Rif1; Sld3; cell cycle; DNA replication; genome instability; pre-RC; re-replication; ubiquitylation; cyclin-dependent kinase; geminin; Origin Recognition Complex (ORC); Minichromosome Maintenance (MCM); Mec1/ATR; replication–transcription conflict; checkpoint; DNA damage response; stress response; R-loop; primase; polymerase; AEP; PrimPol; DNA replication; priming; translesion synthesis; damage tolerance; translesion synthesis; replication stress; transcriptional regulation; polymerase interactions; polymerase domains; polymerase modifications; P. aeruginosa phage PaP1; DNA polymerase; 8-oxoG; steady-state kinetics; pre-steady-state kinetics; nucleotide incorporation; initiation of DNA replication; DnaA; oriC; regulation of DNA replication; Bacillus subtilis; sporulation; DNA damage; DNA lesion bypass; DNA polymerase; genomic instability; mutagenesis; translesion synthesis; DNA helicase; DNA replication; initiation; protein-DNA interaction; DnaA; Large T antigen; E1 helicase; Mcm2–7; melting; replication; centromere; heterochromatin; fragile site; Swi6; Fork Protection Complex; cohesion; development; S-phase; cell cycle; Xenopus; Drosophila; translesion synthesis; checkpoint; replication; mutagenesis; cancer; APOBEC; mismatch repair; polymerase delta; polymerase epsilon; replication stress; nucleotide pools; DNA replication; chromatin assembly; DNA damage tolerance; replication fork stability; homologous recombination; DNA re-replication; endoreplication; mitotic slippage; Geminin; teratoma; teratocarcinoma; embryonic stem cells; embryonal carcinoma cells; cancer stem cells; germ cell neoplasia; DNA replication; genome integrity; chromatin; PCNA; RFC complex; PCNA loader; PCNA unloader; RFC1; Ctf18; Elg1; replication control; RNA:DNA hybrid; transcription‐initiated replication; Telomere; Telomere replication; G‐quadruplex; T‐loop; TERRA; dNTP; DNA polymerase; genome instability; ribonucleotide reductase; replication fidelity; proofreading; DNA replication; replication origin; Orc1/Cdc6; archaea; Sulfolobus; Haloferax; DNA damage tolerance; post replication repair; DNA damage response; trans-lesion synthesis; template switching; DNA replication; human; primosome; primase; DNA polymerase α; protein-DNA interaction; RNA synthesis; initiation; termination; steric hindrance; CMG helicase; DNA replication; genome stability; Mcm10; origin activation; replication initiation; replication elongation; DNA damage; intra-S checkpoint; ATR; Chk1; fork stability; origin regulation; DNA replication; DNA replication stress; checkpoint response; Chk1; E2F-dependent transcription; E2F6; oncogene-induced replication stress; n/a; DNA replication; replication fork; difficult‐to‐replicate; replication machinery; replisome; natural impediments; DNA damage; repetitive DNA; secondary structures; genomic instability; cyclin-dependent kinase; Dbf4-dependent kinase; mitosis; meiosis; genome duplication; meiotic recombination; quantitative model; DNA replication; mammalian chromosome; replication domain; replication foci; replication origin; DNA replication; genome integrity; telomere; shelterin; G-quadruplex; RecQ-like helicase; fragile telomere; replication fork barrier; dormant origin; DNA replication; checkpoints; ribonucleotide reductase; PCNA; CRL4Cdt2; intrinsically disordered proteins; deoxynucleotide salvage; fission yeast; DnaA; N-terminus of DnaA; oriC; chromosomal replication; orisome; HobA; DiaA; SirA; Hda; Dps; DnaB; DNA polymerase δ; PDIP46; Poldip3; PDIP38; Poldip2; DNA replication; enzyme regulation; DNA damage response; p12 subunit; E3 ligases; cell cycle; archaeal RecJ; Cdc45-MCM-GINS; nuclease; GINS; interaction
