Diagnosis, Management, and Prognostic Assessment of Chronic Disease

Dear Colleagues,

Chronic diseases—such as heart disease, cancer, diabetes, stroke, and arthritis—are the leading causes of disability and death throughout the world. In fact, 63% of all deaths worldwide are from chronic conditions. Chronic diseases constitute a major cause of mortality, and the World Health Organization (WHO) attributes 38 million deaths a year to non-communicable diseases. In the United States, approximately 40% of adults have at least two chronic conditions. Living with two or more chronic conditions is referred to as multimorbidity. Chronic diseases tend to occur in older adults and can usually be controlled, but not cured. The most common types of chronic disease are cancer, heart disease, stroke, diabetes, and arthritis. Subsequently, there is growing international interest in the potential diagnosis, management, and prognostic assessment of patients with chronic conditions. As treatment often centers around timely and comprehensive therapies, there is an urgent need to identify risk factors and effective diagnostic and treatment strategies to reduce morbidity, decrease disease recurrence, and improve survival rates. This Special Issue aims to cover novel state-of-the-art research on basic and clinical findings in relation to chronic diseases. Submissions should clarify the substantive improvements on work that has already been published, accepted for publication, or submitted in parallel to other conferences or journals.

Topics of interest include, but are not limited to, the following:

• Biomarkers for chronic diseases and their complications;
• Discovery of novel diagnostic and prognostic markers in chronic diseases;
• Genomic research for chronic diseases and their complications;
• Epigenomic research for chronic diseases;
• Metabolic syndrome and chronic diseases;
• Metabolic syndrome and cancers;
• Metabolic abnormalities and chronic diseases;
• Nutrition and metabolism for chronic diseases;
• Drug use and chronic diseases;
• Molecular mechanisms;
• Predictive models;
• Non-alcoholic fatty liver disease;
• Obesity;
• Cardiovascular disease.

Dr. Xiude Fan
Dr. Enfa Zhao
Dr. Yang Xia
Dr. Shanshan Shao
Dr. Tatsunori Miyata
Dr. Dongxing Xie
Topic Editors