Canine Distemper Virus

Dear Colleagues,

Canine distemper virus (CDV) is a virus of the genus Morbillivirus that causes a highly contagious, acute, and fatal disease, canine distemper (CD). CDV is a multi-host pathogen with a worldwide distribution, affecting a wide range of wild and domestic species of the Carnivora order. The CDV genome encodes eight viral proteins, two of which are more variable than other CDV proteins, suitable for genetic lineage identification, phylogenetic analysis, and useful markers for evolutionary studies, and likely related to the high geographic distribution and host diversity. Dogs are considered the major reservoir host for CDV, and wildlife is not only a reservoir for CDV, but many species are susceptible to disease. Spillover from canine reservoirs to wildlife species has led to high mortality outbreaks that represent a major conservation threat.

The aim of this Special Issue is to review current research on CDV epidemiology and pathogenesis. Topics of interest include, but are not limited to, the following:

- Worldwide spread of this cosmopolitan virus.

- Plasticity of its geographical distribution.

- The rapid evolution of lineages due to the high variation capacity of its H gene or other factors.

- High similarity to human measles and other morbilliviruses.

- The high frequency of the emergence of new carnivorous hosts.

- The occurrence of epidemic outbreaks in wild species.

- Environmental factors likely to affect distribution and occurrence.

Prof. Dr. Monica G. Candela
Prof. Dr. Nieves Ortega Hernández
Guest Editors

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• CDV taxonomy (lineages)
• new hosts of CDV
• CDV pathogenesis
• CDV epidemiology (risk factors, distribution, and prevalence)
• CDV prevention/risk mitigation