Environmental and Occupational Exposure to Chemical Agents and Health Challenges II

Dear Colleagues,

Human beings live in constant contact with chemical agents—mainly through environmental exposure—which are derived from the occupational setting. Environmental exposure is ubiquitous, originating from air, water, and soil. While some chemicals are short-lived in the environment and may elicit no harmful effects in humans, other chemicals bioaccumulate or persist for a long time in the environment or the human body due to frequent exposure. However, environmental exposure also includes diet, lifestyle, and hobbies, and exposure to other substances such as drugs, food additives, pesticides, and nanomaterials, among other daily products, which are significant areas of research. Occupational exposure concerns the potentially harmful exposure to hazardous chemicals in the workplace; however, more specifically, it involves permanent and substantial contact with the determined substances. Possible health effects can arise from these types of exposure, which can be measured and prevented by biomonitoring, and the outcome should be integrated to ensure better regulatory decision making. With that objective and on behalf of this study, translation research should be conducted by using in vitro studies with exposures from real context scenarios adding to the body of knowledge and providing a better understanding of human biomonitoring outcomes, mainly in the chemical mixtures effects assessment.

The expectation is that the results taken from these studies can add data and integrated information to encourage national and international bodies to make decisions such as setting allowable concentrations for a wide range of substances from environmental and occupational exposures, with particular attention paid to newly identified chemical mixtures and agents, which should be swiftly regulated.

Dr. Carina Ladeira
Guest Editor

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• environmental exposure
• occupational exposure
• chemical agents
• exposome
• chemical mixtures
• regulatory toxicology
• health prevention