Special Issue "Bioconjugates/Biohybrid Polymers"
A special issue of Polymers (ISSN 2073-4360).
Deadline for manuscript submissions: closed (31 December 2012)
Prof. Dr. Helmut Schlaad
1 University of Potsdam, Institute of Chemistry, Karl-Liebknecht-Str. 24-25, 14476 Potsdam, Germany
2 Max Planck Institute of Colloids and Interfaces, Department of Colloid Chemistry, Research Campus Golm, 14424 Potsdam, Germany
Phone: +49 331 567 9514
Fax: +49 331 567 9502
Interests: methods of living/controlled ionic polymerization and ring-opening polymerization of heterocycles; polymer modification, "thio-click" chemistry; size-exclusion chromatography; polymer colloids and films, composite materials; bioinspired structure formation of polymers, hierarchical structures, polymer complexes
Bioorganic-synthetic polymer conjugates, also referred to as biohybrids, are built up from biomolecules (e.g., peptide sequence, protein, sugar, polysaccharide, DNA/RNA, terpene) and synthetic polymers, aiming to combine the advantageous properties of the two components, namely biological function, molecular recognition, chirality, etc. (biological component) and solution properties, processability, etc. (synthetic component). Although the first bioconjugate polymers have already been reported more than 40 years ago, it still remains a challenge to produce well-defined samples on larger scale. This goal has recently been approached with the developments of “living”/controlled polymerization techniques and improved coupling techniques, i.e., PEGylation and “click” chemistry.
This special issue is intended to highlight recent advances in the controlled synthesis and characterization of bioconjugate polymers as well as their use in the biomedical field (drug delivery/targeting, diagnostics, etc.), supramolecular and colloid science, materials science, and so on.
Dr. Helmut Schlaad
- synthesis and characterization
- structure formation
Polymers 2013, 5(2), 431-526; doi:10.3390/polym5020431
Received: 22 March 2013; in revised form: 1 May 2013 / Accepted: 3 May 2013 / Published: 21 May 2013| Cited by 6 | PDF Full-text (2913 KB) | HTML Full-text | XML Full-text
Review: Application of Chondroitin Sulfate Derivatives for Understanding Axonal Guidance in the Nervous System during Development
Polymers 2013, 5(1), 254-268; doi:10.3390/polym5010254
Received: 12 January 2013; in revised form: 28 January 2013 / Accepted: 17 February 2013 / Published: 25 February 2013| PDF Full-text (364 KB) | HTML Full-text
Article: Controlled Release of Damascone from Poly(styrene-co-maleic anhydride)-based Bioconjugates in Functional Perfumery
Polymers 2013, 5(1), 234-253; doi:10.3390/polym5010234
Received: 23 January 2013; in revised form: 18 February 2013 / Accepted: 19 February 2013 / Published: 22 February 2013| Cited by 1 | PDF Full-text (950 KB) | HTML Full-text | XML Full-text
Review: Hybrid Block Copolymers Constituted by Peptides and Synthetic Polymers: An Overview of Synthetic Approaches, Supramolecular Behavior and Potential Applications
Polymers 2013, 5(1), 188-224; doi:10.3390/polym5010188
Received: 7 January 2013; in revised form: 1 February 2013 / Accepted: 1 February 2013 / Published: 11 February 2013| Cited by 5 | PDF Full-text (2953 KB)
Polymers 2013, 5(1), 161-187; doi:10.3390/polym5010161
Received: 4 January 2013; in revised form: 1 February 2013 / Accepted: 4 February 2013 / Published: 8 February 2013| Cited by 7 | PDF Full-text (482 KB)
Last update: 4 March 2014