Conferences
6–9 September 2016, Homburg, Germany
8th International Conference on Protein Kinase CK2
Protein kinase CK2 is a serine/threonine kinase which is highly conserved in evolution. Knock-out experiments have shown that this enzyme is absolutely necessary for cell viability. The enzyme is highly expressed in rapidly proliferating cells which goes along with an elevated enzyme activity. Protein kinase CK2 is involved in a broad range of signaling pathways regulating proliferation, differentiation, apoptosis or senescence. Recent advances towards the characterization of the three dimensional structure of protein kinase CK2 and its subunits will undoubtedly yield important new insights into its regulation and functions of CK2. Moreover, with two inhibitors of the enzyme in clinical trials phase II at current, human protein kinase CK2 appears as an emerging target for cancer diseases.
