Structural Biology in Non-coding RNA Biogenesis and Function

Dear Colleagues,

Structural biology techniques and protocols have evolved rapidly in the last decade. This can be exemplified by the development and design of new X-ray detectors and through the adaptation of sample processing strategies for improving the resolution in cryo-electron microscopy. Application of these structural methods to the characterization of the biogenesis and function of non-coding RNAs has led to very important contributions to the overall understanding of regulatory RNAs. Moreover, modifications of next-generation sequencing protocols for transcriptome-wide structure probing of RNA molecules have also demonstrated the dynamic nature of non-coding RNAs under physiological conditions.

This Special Issue is devoted to the application of structural biology for the functional characterization of non-coding RNAs and their partners. Original research as well as critical reviews analyzing specific topics are welcomed.

Prof. Dr. Francisco J. Enguita
Guest Editor

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• structural biology
• non-coding RNAs
• X-ray crystallography
• cryo-electron microscopy
• high-throughput methods
• structure profiling