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Microorganisms
Special Issues
State-of-the-Art Medical Microbiology in the USA (2023, 2024)
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State-of-the-Art Medical Microbiology in the USA (2023, 2024)

A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Medical Microbiology".

Deadline for manuscript submissions: 30 September 2024 | Viewed by 2136

Special Issue Editor

Prof. Dr. Deepak Shukla

E-Mail Website
Guest Editor
Ophthalmology & Visual Sciences, Microbiology & Immunology, University of Illinois, Chicago, IL 60612, USA
Interests: herpes simplex virus infection; viral glycoproteins; antiviral agents; viral vaccines; ocular infection; heparan sulfate proteoglycans; heparanase

Special Issue Information

Dear Colleagues,

This Special Issue aims to provide a comprehensive overview of state-of-the-art medical microbiology in the USA. We encourage American researchers from related fields to contribute papers highlighting the latest developments in medical microbiology, or to invite relevant experts and colleagues to do so. This Special Issue will publish full research articles and comprehensive reviews.

Prof. Dr. Deepak Shukla
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Microorganisms is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Published Papers (1 paper)

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Review

14 pages, 285 KiB  
Review
Heartland Virus Disease—An Underreported Emerging Infection
by Zygmunt F. Dembek, Jerry L. Mothershead, Christopher M. Cirimotich and Aiguo Wu
Microorganisms 2024, 12(2), 286; https://doi.org/10.3390/microorganisms12020286 - 29 Jan 2024
Viewed by 1885
Abstract
First recognized 15 years ago, Heartland virus disease (Heartland) is a tickborne infection contracted from the transmission of Heartland virus (HRTV) through tick bites from the lone star tick (Amblyomma americanum) and potentially other tick species. Heartland symptoms include a fever [...] Read more.
First recognized 15 years ago, Heartland virus disease (Heartland) is a tickborne infection contracted from the transmission of Heartland virus (HRTV) through tick bites from the lone star tick (Amblyomma americanum) and potentially other tick species. Heartland symptoms include a fever <100.4 °F, lethargy, fatigue, headaches, myalgia, a loss of appetite, nausea, diarrhea, weight loss, arthralgia, leukopenia and thrombocytopenia. We reviewed the existing peer-reviewed literature for HRTV and Heartland to more completely characterize this rarely reported, recently discovered illness. The absence of ongoing serosurveys and targeted clinical and tickborne virus investigations specific to HRTV presence and Heartland likely contributes to infection underestimation. While HRTV transmission occurs in southern and midwestern states, the true range of this infection is likely larger than now understood. The disease’s proliferation benefits from an expanded tick range due to rising climate temperatures favoring habitat expansion. We recommend HRTV disease be considered in the differential diagnosis for patients with a reported exposure to ticks in areas where HRTV has been previously identified. HRTV testing should be considered early for those matching the Heartland disease profile and nonresponsive to initial broad-spectrum antimicrobial treatment. Despite aggressive supportive therapy, patients deteriorating to sepsis early in the course of the disease have a very grim prognosis. Full article
(This article belongs to the Special Issue State-of-the-Art Medical Microbiology in the USA (2023, 2024))
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