Special Issue "Marine Dinoflagellates"


A special issue of Marine Drugs (ISSN 1660-3397).

Deadline for manuscript submissions: closed (30 June 2014)

Special Issue Editor

Guest Editor
Dr. Andrea Bourdelais
Center for Marine Science, University of North Carolina at Wilmington, 5600 Marvin K. Moss Lane, Wilmington NC, 28409, USA
E-Mail: bourdelaisa@uncw.edu
Phone: +1 910 962 2365
Fax: +1 910 962 2410
Interests: isolation and structure elucidation of bioactive marine natural products; polyether compounds; bioassay screening; high content screening; quantitative analysis of marine toxins; harmful algal blooms; Florida red tide; marine dinoflagellates

Special Issue Information

Dear Colleagues,

Dinoflagellates comprise a diverse class of flagellated protists found in marine and fresh water environments. Of the approximately 2000 living species about 1700 species are found in marine environments. Due to the complex nature of the marine environment these microorganisms have developed unique biosynthetic machinery for the production of metabolites with unusual chemical structures and potent biological activities. Naturally produced chemical families include polyethers, macrolides, polyhydroxy compounds, heterocycles, polyketals, amino acids, terpenes, phytopigments, and purine derivatives. Although metabolites produced by these micro-organisms are known for their cytotoxicity, many have show selective activity in biological systems for example: saxitoxins are selective sodium channel blockers, brevetoxins and ciguatoxins selectively activate sodium channels, and maitotoxins act on calcium channels. Other metabolites have been found to inhibit enzymes (okadaic acid), yet others have show potent activity as anti-fungal (gamberic acids) or anti-tumor (amphidinols) agents. Because of their unprecedented biosynthetic capabilities and ease of culture, dinoflagellates provide a renewable source for novel chemical structures that may be used as biological tools or drug candidates. This special issue will be devoted to the bioactivity of both natural and chemically modified dinoflagellate metabolites as well the biosynthetic pathways involved in their production.

Dr. Andrea J. Bourdelais
Guest Editor


Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Marine Drugs is an international peer-reviewed Open Access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs).


  • marine natural products
  • bioactive metabolites
  • microalgae
  • mechanism of action
  • therapeutic potential
  • polyethers
  • phytopigments
  • lipids
  • marine toxins
  • bioassays
  • culturing
  • bioactive compounds
  • symbiotic relationships
  • natural defenses
  • biosynthesis
  • semisynthetic derivatives
  • bioactivity
  • structure activity relationships
  • environmental impact

Published Papers (3 papers)

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Displaying article 1-3
p. 4743-4755
by , ,  and
Mar. Drugs 2014, 12(9), 4743-4755; doi:10.3390/md12094743
Received: 1 July 2014; in revised form: 18 August 2014 / Accepted: 26 August 2014 / Published: 5 September 2014
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(This article belongs to the Special Issue Marine Dinoflagellates)
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p. 1011-1048
by , , ,  and
Mar. Drugs 2010, 8(4), 1011-1048; doi:10.3390/md8041011
Received: 24 February 2010; in revised form: 17 March 2010 / Accepted: 26 March 2010 / Published: 31 March 2010
Show/Hide Abstract | Cited by 15 | PDF Full-text (423 KB) | HTML Full-text | XML Full-text | Supplementary Files
(This article belongs to the Special Issue Marine Dinoflagellates)
p. 763-809
by  and
Mar. Drugs 2010, 8(3), 763-809; doi:10.3390/md8030763
Received: 25 February 2010; in revised form: 11 March 2010 / Accepted: 18 March 2010 / Published: 19 March 2010
Show/Hide Abstract | Cited by 19 | PDF Full-text (3185 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Marine Dinoflagellates)
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Last update: 12 November 2013

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