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Marine Drugs
Special Issues
Discoveries of Bioactive Compounds from Algae
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Discoveries of Bioactive Compounds from Algae

A special issue of Marine Drugs (ISSN 1660-3397). This special issue belongs to the section "Marine Biotechnology Related to Drug Discovery or Production".

Deadline for manuscript submissions: closed (1 March 2024) | Viewed by 1574

Special Issue Editor

Prof. Dr. Sylvia Urban

E-Mail Website
Guest Editor
School of Science (Applied Chemistry and Environmental Science), RMIT University, Melbourne, Australia
Interests: marine and terrestrial natural products chemistry; isolation and structural characterization; NMR spectroscopy; analytical separation methodologies
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Bioactive compounds derived from algae still comprise an important and active area of research in the field of drug discovery. This Special Issue of Marine Drugs invites scholars to submit research into algae and aims to highlight new isolation and structural elucidation approaches, and developments in drug discovery, synthesis and medicinal chemistry, structural methods, chemical biology and biotechnology, and genomic tools. Additionally, we will publish studies on metabolomics and bioassay-guided and chemical profilin methodologies to expedite discoveries and advance potential therapeutics. This Special Issue invites reviews and original contributions in any of these areas.

Prof. Sylvia Urban
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Marine Drugs is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • algae
  • drug discovery
  • medicinal chemistry
  • structural methods
  • chemical approaches
  • metabolomics

Published Papers (1 paper)

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Research

22 pages, 2121 KiB  
Article
An Eco-Friendly Extraction and Purification Approach for Obtaining Active Ingredients for Cosmetics from Two Marine Brown Seaweeds
by Leslie Gager, Solène Connan, Stéphane Cérantola, Sylvain Petek, Céline Couteau, Laurence Coiffard and Valérie Stiger-Pouvreau
Mar. Drugs 2024, 22(3), 112; https://doi.org/10.3390/md22030112 - 28 Feb 2024
Cited by 1 | Viewed by 1345
Abstract
Brown seaweeds are attracting attention due to their richness in bioactive compounds, in particular, their phlorotannins. We present here a case study of two Fucales, Ascophyllum nodosum and Halidrys siliquosa, sustainably collected, to produce active polyphenols for the cosmetics sector. Phenolic contents of [...] Read more.
Brown seaweeds are attracting attention due to their richness in bioactive compounds, in particular, their phlorotannins. We present here a case study of two Fucales, Ascophyllum nodosum and Halidrys siliquosa, sustainably collected, to produce active polyphenols for the cosmetics sector. Phenolic contents of crude extracts, obtained by Accelerated Solvent Extraction (ASE), were more elevated in H. siliquosa at 100.05 mg/g dry weight (DW) than in A. nodosum (29.51 mg/g DW), considering 3 cycles with cell inversion. The temperature of extraction for a high phenolic content and high associated antioxidant activities close to positive controls was 150 °C for both algae and the use of only one cycle was enough. A semi-purification process using Solid-phase Extraction (SPE) was carried out on both ASE crude extracts (one per species). The majority of phlorotannins were found in the ethanolic SPE fraction for A. nodosum and the hydroethanolic one for H. siliquosa. The SPE process allowed us to obtain more concentrated fractions of active phenolic compounds (×1.8 and 2 in A. nodosum and H. siliquosa, respectively). Results are discussed in regard to the exploitation of seaweeds in Brittany and to the research of sustainable processes to produce active natural ingredients for cosmetics. Full article
(This article belongs to the Special Issue Discoveries of Bioactive Compounds from Algae)
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