New Perspectives on the Diagnosis and Treatment of Liver Cirrhosis

Dear Colleagues,

Liver cirrhosis is the end stage of chronic liver diseases. Diagnosis typically involves a combination of medical history, physical examination, imaging studies (such as ultrasound), and blood tests to assess liver function. Treatment aims to manage the underlying cause of cirrhosis, alleviate symptoms, and prevent complications. Lifestyle changes, medications, and, in severe cases, liver transplantation may be recommended. There are two recognized stages of liver cirrhosis: compensated and decompensated liver cirrhosis with different outcomes and prognosis.

The principal aim of this Special Issue is to delve deeply into non-invasive diagnosis for liver cirrhosis, specifically focusing on the non-invasive diagnosis of emerging etiologies as MASLD. Additionally, we seek to broaden our understanding of non-invasive diagnostic approaches related to portal hypertension, covering clinically significant portal hypertension and the presence of esophago-gastric varices. In this context, particular emphasis will be placed on exploring ultrasound and elastography techniques.

Furthermore, this Special Issue endeavors to examine potential treatments aimed at preventing clinical complications in compensated liver cirrhosis. For decompensated liver cirrhosis, our exploration will encompass both novel interventions to mitigate mortality and an assessment of the prognostic role played by non-invasive markers.

We encourage your active participation in this Special Issue dedicated to liver cirrhosis.

Dr. Elba Llop
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• liver cirrhosis
• portal hypertension
• non-invasive diagnosis
• elastography
• gastro-esophagueal varices