Technological Advances, Innovative Applications, and New Clinical Benefits of Computed Tomography

Dear Colleagues,

Following its commencement in the 1970s, computed tomography (CT) has undergone continuous technological developments, changing from a morphological imaging technique alone to one that also includes different functional parameters, e.g., tissue perfusion. Nowadays, the introduction of new dual-energy and spectral CT systems based on dual-source or dual-layer technologies are overcoming the conventional limitations of tissue characterization. Spectral reconstructions based on virtual monoenergetic images, virtual noncontrast images, iodine maps, and Z-effective images allow us to obtain images with lower radiation doses, reduced contrast agent volumes, fewer artifacts, and tissue characterization. CT systems equipped with photon-counting detectors, directly converting photons into electric signals, can improve the degree of spatial resolution, reduce noise and blooming artifacts, and accurately assess stent patency and the degree of stenosis. These technological advances, combined with innovative applications, are progressively changing the traditional working methods of the radiological community worldwide. Artificial intelligence and radiomics, which enable the automation of processes such as image segmentation or lesion detection, as well as obtaining information in terms of biomarkers, will be emphasized in this Special Issue. We welcome authors to submit papers based on technological advances and innovative applications of CT that are capable of providing new clinical benefits.

Prof. Dr. Massimo Venturini
Prof. Dr. Federico Fontana
Guest Editors

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• computed tomography (CT)
• spectral CT
• dual-energy CT
• dual-source spectral CT
• dual-layer spectral CT
• pho-ton-counting CT
• photon-counting detector CT
• spectral photon-counting CT
• artificial intelligence
• radiomics