Chronic Obstructive Pulmonary Disease (COPD)—Clinical Aspects, Early Detection and Pathogenesis

Dear Colleagues,

Chronic Obstructive Pulmonary Disease (COPD) is a major cause of morbidity and mortality all over the world. The main causes of the disease are well known: exposure to noxious gases and cigarette smoking. The precise pathogenesis is vague. We still do not know why some heavy smokers develop COPD and others do not. COPD is a heterogenous disease. The clinical course might be different and the treatment should be personalized according to the phenotype. COPD diagnosis is based on clinical symptoms and a pulmonary function test. Most patients are not diagnosed properly. Underdiagnosis and overdiagnosis are still significant issues and early detection is still under debate. The medical literature on COPD is extensive, but there are many unanswered questions. We intend to publish a Special Issue with the aim of answering some of these questions and raising new ones. We would be glad to accept manuscripts dealing with the clinical aspects of COPD, as well as the early detection of COPD and pathogenesis of the disease from a clinician’s point of view.

Prof. Dr. Gabriel Izbicki
Prof. Dr. Yochai Adir
Dr. Ariel Rokach
Guest Editors

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• COPD
• pathophysiology
• pulmonary function test
• acute exacerbation
• neutrophils
• eosinophils
• early detection