Risk Factors, Diagnosis, and Treatment of Cardiovascular Disease

A special issue of Journal of Cardiovascular Development and Disease (ISSN 2308-3425). This special issue belongs to the section "Cardiovascular Clinical Research".

Deadline for manuscript submissions: closed (31 January 2024) | Viewed by 3196

Special Issue Editors


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Guest Editor
1. Department of Cardiothoracic Surgery, Amsterdam University Medical Center (AUMC), 1105 AZ Amsterdam, The Netherlands
2. Department of Cardiothoracic Surgery, Leiden University Medical Center (LUMC), 2333 ZA Leiden, The Netherlands
3. Department of Anatomy and Embryology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands
Interests: aortic valve; heart valve diseases; vascular surgery; aneurysm cardiac surgery; aortic diseases; atherosclerotic vascular diseases; cardiovascular surgery; coronary artery bypass surgery; endovascular surgery
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Guest Editor
Department of Cardiovascular Surgery, Medical Center–University of Freiburg, Faculty of Medicine, University of Freiburg, Hugstetter Str. 55, 79106 Freiburg, Germany
Interests: aortic valve; heart valve diseases; vascular surgery; aneurysm cardiac surgery; aortic diseases; atherosclerotic vascular diseases; cardiovascular surgery; coronary artery bypass surgery; endovascular surgery

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Guest Editor
Department of Translational Medical Sciences, University of Campania "Luigi Vanvitelli" - Cardiac Surgery Unit, V. Monaldi Hospital, via L. Bianchi, 80131 Naples, Italy
Interests: aortic valve; heart valve diseases; vascular surgery; aneurysm cardiac surgery; aortic diseases; atherosclerotic vascular diseases; cardiovascular surgery; coronary artery bypass surgery; endovascular surgery

Special Issue Information

Dear Colleagues,

Cardiovascular diseases (CVDs) continue to be the leading cause of death, disability, and high healthcare costs around the world. Despite substantial advances in patient care, the incidence of CVD continues to increase. Therefore, cardiovascular risk factors, diagnostic options, and treatment strategies desperately need to be understood in order to reduce morbidity and mortality rates and improve quality of life.

On these grounds, this Special Issue intends to explore the latest developments in the field of cardiac diseases, with a particular focus on the risk factors, prevention, and management of CVD.

The Special Issue Guest Editors welcome the submission of original investigations, review articles, and short communications on any of the following topics:

  • The incidence, etiology, and/or prevention of cardiovascular diseases, especially in diverse groups of patients;
  • Fundamental basic science research into development mechanisms of cardiovascular disease;
  • Bench-to-bedside translational research in cardiovascular diseases;
  • Approaches on the better management and treatment of cardiovascular diseases.

Dr. Nimrat Grewal
Prof. Dr. Martin Czerny
Dr. Alessandro Della Corte
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Cardiovascular Development and Disease is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • atherosclerosis
  • heart valve disease
  • cardiovascular disease
  • heart failure
  • pulmonary hypertension
  • cardiac surgery
  • cardiac arrythmias
  • metabolic syndrome

Published Papers (2 papers)

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Research

10 pages, 1188 KiB  
Article
Serum Copper Concentrations, Effect Modifiers and Blood Pressure: Insights from NHANES 2011–2014
by Ruo-Nan Xu, Yue Zhang, Xin Xu, Xu Li, Lan He, Qiang Feng, Yong-Hai Yang, Yang He, Xiao Ma and Yong-Ming He
J. Cardiovasc. Dev. Dis. 2023, 10(10), 432; https://doi.org/10.3390/jcdd10100432 - 18 Oct 2023
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Abstract
(1) Background: Epidemiological studies on the relationship between serum copper and hypertension are contradictory. We assessed the relationship between serum copper and blood pressure among adults in the United States. (2) Methods: We divided hypertension into two categories: treated hypertension and untreated hypertension. [...] Read more.
(1) Background: Epidemiological studies on the relationship between serum copper and hypertension are contradictory. We assessed the relationship between serum copper and blood pressure among adults in the United States. (2) Methods: We divided hypertension into two categories: treated hypertension and untreated hypertension. Linear or logistic regression analysis was applied to investigate the association between serum copper concentrations and blood pressure levels. (3) Results: As compared to quartile 1, the odds ratios (ORs) for untreated hypertension in quartiles 2, 3, and 4 were 1.02 (0.74–1.42), 1.23 (0.88–1.72), and 1.08 (0.74–1.58), respectively, in multivariable analysis (all p > 0.05). In non-hypertension, as compared with quartile 1, the β (95% CI) of systolic blood pressure for quartiles 2, 3, and 4 was −0.92 (−2.07–0.23), −0.05 (−1.30–1.20), and −0.48 (−1.83–0.88), respectively, in multivariable analysis (all p > 0.05). As compared to quartile 1, the ORs for treated hypertension in quartiles 2, 3, and 4 were 1.36 (0.88–2.10), 1.35 (0.87–2.09), and 1.56 (0.98–2.47), respectively, upon multivariable analysis including antihypertensive medication use as a covariate (all p > 0.05). Furthermore, 1SD increase in serum copper was non-significantly associated with 1.16 (0.97–1.37)-fold increased risk of hypertension in multivariable analysis (p = 0.096). (4) Conclusion: In the present study, we discovered that the serum copper concentration was not related with hypertension or blood pressure levels. Antihypertensive drug use may distort the correlation between copper and blood pressure levels. Information on antihypertensive drug use may be taken into account when identifying new risk factors for hypertension. Full article
(This article belongs to the Special Issue Risk Factors, Diagnosis, and Treatment of Cardiovascular Disease)
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13 pages, 993 KiB  
Article
Long-Term Prognosis of Different Subtypes of Left Ventricular Noncompaction Cardiomyopathy Patients: A Retrospective Study in China
by Shiqi Gao, Shuyuan Zhang, Zeyuan Wang, Ming Wu, Chengying Gu, Ruilian Bai, Meixi Liu, Zhuang Tian and Shuyang Zhang
J. Cardiovasc. Dev. Dis. 2023, 10(9), 369; https://doi.org/10.3390/jcdd10090369 - 28 Aug 2023
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Abstract
Left ventricular noncompaction (LVNC) is a heterogeneous cardiomyopathy that can be classified into different subtypes based on morphologic and functional features. However, the prognosis of the dilated and isolated subtypes of non-pediatric LVNC remains unknown. We retrospectively studied 101 patients with LVNC diagnosed [...] Read more.
Left ventricular noncompaction (LVNC) is a heterogeneous cardiomyopathy that can be classified into different subtypes based on morphologic and functional features. However, the prognosis of the dilated and isolated subtypes of non-pediatric LVNC remains unknown. We retrospectively studied 101 patients with LVNC diagnosed at Peking Union Medical College Hospital from 2006 to 2022 using the Jenni criteria of transthoracic echocardiography. The patients were grouped into those with dilated LVNC (n = 64) or isolated LVNC (n = 37), and 88 patients (54 with dilated LVNC and 34 with isolated LVNC) were followed up successfully. The primary outcome was major adverse cardiovascular events (a composite of cardiovascular mortality, heart failure, severe ventricular arrhythmia, and systolic embolism). The median follow-up time was 5.24 years. The incidence of major adverse cardiovascular events was 43.2%; patients with dilated LVNC had a higher risk (adjusted hazard ratio, 4.43; 95% confidence interval, 1.24–15.81; p = 0.02) than those with isolated LVNC. None of the isolated LVNC patients had cardiovascular deaths or severe ventricular arrhythmias. The risk of systemic embolism was similar between patients with dilated and isolated LVNC. Our findings indicate that transthoracic echocardiography is a useful tool for classifying LVNC into subtypes with distinct clinical outcomes. Dilated LVNC is associated with a poor prognosis, while the isolated subtype is probably a physiological condition. Full article
(This article belongs to the Special Issue Risk Factors, Diagnosis, and Treatment of Cardiovascular Disease)
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