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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic. The journal’s Editor-in-Chief and/or designated EBM will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Mesenchymal Stem Cells Differentiation in Health and Disease
edited by
submission deadline 30 Apr 2024 | 3 articles | Viewed by 5689
Keywords: mesoderm; mesenchymal stem cells; osteogenic differentiation; chondrogenic differentiation; adipogenic differentiation; MSC clinical applications
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Monoclonal Antibodies and Their Functional Fragments in Research, Diagnosis and Therapy 3.0 submission deadline 30 Apr 2024 | 2 articles | Viewed by 5604
Keywords: Mabs; Fabs; ScFv; nanobodies; biomarker detection; bispecific antibodies; analyte detection; sandwich assays
(This special issue belongs to the Section Macromolecules)
DNA Damage Repair in Cancer: Genetics, Molecular Mechanisms, Diagnostic and Therapeutic Perspectives submission deadline 30 Apr 2024 | 3 articles | Viewed by 5498
Keywords: DNA damage and repair; genomic instability; cancer therapy; cancer resistance; biomarkers
(This special issue belongs to the Section Molecular Oncology)
Aquatic Biotechnology and Its Application in Genetic Breeding
edited by
submission deadline 30 Apr 2024 | 5 articles | Viewed by 5495
Keywords: aquaculture; biotechnology; germplasm improvement; genetic breeding; gene function; genomics; gene editing
(This special issue belongs to the Section Molecular Genetics and Genomics)
Exploring Novel Molecular, Metabolic and Cellular Mechanisms for Developing New Therapeutic Targets against Childhood Cancers submission deadline 30 Apr 2024 | 5 articles | Viewed by 5310
Keywords: childhood cancers; rhabdomyosarcoma; leukemias; lymphomas; central nervous system tumors; sarcomas of bone and soft tissue; neuroblastoma; retinoblastoma; rhabdoid tumors; rare cancers; genomic alterations; molecular drivers; tissue microenvironment; development of drugs; therapies
(This special issue belongs to the Section Molecular Oncology)
Melanoma: From Molecular Pathology to Therapeutic Approaches
edited by
submission deadline 30 Apr 2024 | 4 articles | Viewed by 5277
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Novel Molecular Pathways in Oncology 2.0
edited by
submission deadline 30 Apr 2024 | 4 articles | Viewed by 5098
Keywords: molecular pathway involved in tumorigenesis; cancer therapy; targeted therapy; anticancer drugs; brain cancer; oral cancer; gastrointestinal cancer
(This special issue belongs to the Section Molecular Oncology)
Advances in the Prevention and Treatment of Ischemic Diseases
edited by
submission deadline 30 Apr 2024 | 4 articles | Viewed by 5088
Keywords: stroke; acute kidney injury; dietary approaches; liver ischemia; heart attack; stem cells; hypoxia; preconditioning; antioxidants
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Aspects of Haemorrhagic and Thrombotic Disorders submission deadline 30 Apr 2024 | 4 articles | Viewed by 5064
Keywords: next-generation sequencing; whole-exome sequencing; haemorrhagia; thrombosis; molecular biology; diagnosis; genetics; blood coagulation disorders; inherited
(This special issue belongs to the Section Molecular Biology)
Glioblastoma: State of the Art and Future Trends
edited by
submission deadline 30 Apr 2024 | 2 articles | Viewed by 4992
Keywords: glioblastoma; pediatric high-grade glioma; integrated histomolecular diagnosis; molecular neuropathology; artificial intelligence (AI); bioengineering
(This special issue belongs to the Section Molecular Oncology)
Antiviral Drug Design, Synthesis and Molecular Mechanisms
edited by and
submission deadline 30 Apr 2024 | 4 articles | Viewed by 4983
Keywords: viruses; drug discovery; natural compounds; computer-designed new drugs; structure-based drug design; synthetic compounds; structure– activity relationship; molecular mechanisms
(This special issue belongs to the Section Molecular Pharmacology)
Molecular Mechanisms, Pathogenesis, and Novel Therapeutic Strategies in Cardiovascular Disease
edited by
submission deadline 30 Apr 2024 | 4 articles | Viewed by 4976
Keywords: aneurysm pathobiology; vascular remodeling; extracellular matrix degradation; inflammatory signaling pathways; molecular targets for therapy; autophagy; macrophage; inflammation; immune cell regulation; age-related diseases; therapeutic implications
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Skin, Autoimmunity and Inflammation 2.0 submission deadline 30 Apr 2024 | 2 articles | Viewed by 4894
Keywords: skin diseases; skin immunology; skin autoimmunity; skin inflammation; inflammatory cytokines; biological therapies; immunotherapy; target therapies
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Purinergic Signalling in Physiology and Pathophysiology 2.0
edited by
submission deadline 30 Apr 2024 | 4 articles | Viewed by 4814
Keywords: purinergic signalling; purinome; ATP; ADP; UTP; UDP; UDP-glucose; adenosine; P2X receptors; P2Y receptors; P1 receptors; adenosine receptors; ectoenzymes; nucleotidases; nucleotide release; nucleoside release; nucleotide transport; nucleoside transport
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
The Role of Non‐coding RNAs in Human Health and Diseases
edited by
submission deadline 30 Apr 2024 | 4 articles | Viewed by 4732
Keywords: miRNA; lncRNA; mRNA; genome stability; perinatal; fetus; baby; circadian clock; aging; cell cycle regulation; reproduction; transgenerational epigenetic inheritance
(This special issue belongs to the Section Molecular Genetics and Genomics)
Advances in Plant Breeding and Resistance
edited by
submission deadline 30 Apr 2024 | 4 articles | Viewed by 4700
Keywords: plant phenomics; high-throughput phenotyping; plant cells; plant genomics; plant genetics; gene editing; crop breeding; CRISPR/Cas9; abiotic stress; plant resistance; saline and alkali resistance; drought tolerance; genomics; resistance
(This special issue belongs to the Section Molecular Plant Sciences)
Genetic Insights into Cardiovascular Diseases submission deadline 30 Apr 2024 | 4 articles | Viewed by 4520
Keywords: cardiovascular diseases; heart disease; channelopathy; cardiomyopathy; sudden death; genetic diagnoses; gene therapy; rare mutations; common variants
(This special issue belongs to the Section Molecular Genetics and Genomics)
Biomimetic Materials Applied in the Analytical and Biomedical Fields submission deadline 30 Apr 2024 | 3 articles | Viewed by 4503
Keywords: biomimetics; molecular recognition; imprinted polymers; smart materials; molecular complexes; polymeric biomaterials; biomedical materials; analytical methods; molecular interactions; artificial receptors
(This special issue belongs to the Section Materials Science)
The Role of Microglia in Neurological Disorders
edited by
submission deadline 30 Apr 2024 | 4 articles | Viewed by 4481
Keywords: Alzheimer’ s disease; inflammation; microglia; multiple sclerosis; neurodegenerative diseases; neurological disorders; neuron; Parkinson’ s disease; phagocytosis
(This special issue belongs to the Section Molecular Neurobiology)
Advance in the Study of DNA Methylation 2.0
edited by
submission deadline 30 Apr 2024 | 3 articles | Viewed by 4409
Keywords: DNA methylation; DMNT; TET; bisulfite sequencing; RRBS; epigenetics; aging; cancer
(This special issue belongs to the Section Molecular Genetics and Genomics)
The Emerging Role of RNA in Diseases and Cancers 2.0
edited by
submission deadline 30 Apr 2024 | 4 articles | Viewed by 4372
Keywords: long non-coding RNAs; microRNAs; circular RNAs; RNA modifications; RNA editing; mRNA translation; alternative splicing; RNA and protein aggregation; RNA-binding proteins
(This special issue belongs to the Section Biochemistry)
Insights into Mechanisms Underlying Cardiovascular Disease
edited by and
submission deadline 30 Apr 2024 | 2 articles | Viewed by 4307
Keywords: platelets; megakaryocytes; thrombosis; signaling; lipids; inflammation; endothelium; cardiovascular diseases
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Advances in Resistance and Adaptability of Wheat Crops
edited by
submission deadline 30 Apr 2024 | 3 articles | Viewed by 4162
Keywords: biotic and abiotic stress; adaptability; gene cloning; QTL mapping; association analysis; molecular mechanism; functional verification; regulation network; resistant genes; biological breeding
(This special issue belongs to the Section Molecular Plant Sciences)
The Role of NRF2 in Health and Disease submission deadline 30 Apr 2024 | 4 articles | Viewed by 4148
Keywords: Nrf2; disease; inflammation; oxidative stress; therapeutics; animal models studies; in vitro studies
(This special issue belongs to the Section Biochemistry)
Natural Compounds in Health and Disease
edited by
submission deadline 30 Apr 2024 | 4 articles | Viewed by 4033
Keywords: natural compound; antioxidant; anti-inflammatory; anticancer; antimicrobial; antiviral; metabolic disease
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Protein and Nucleotide Engineering for Diagnoses and Biosensing II
edited by , Takenori Satomura, and
submission deadline 30 Apr 2024 | 2 articles | Viewed by 4028
Keywords: proteins; enzymes; antibodies; binding proteins; aptamers; nanozymes; biosensors; diagnosis
(This special issue belongs to the Section Biochemistry)
Advances in the Molecular Diagnostics of Agriculture Pathogens and Pests
edited by
submission deadline 30 Apr 2024 | 4 articles | Viewed by 3982
Keywords: plant pathogens; pests; high-throughput molecular detection; molecular diagnostics; plant pathogenic bacteria
(This special issue belongs to the Section Molecular Plant Sciences)
Epigenetic Regulation in Human Disease
edited by
submission deadline 30 Apr 2024 | 3 articles | Viewed by 3939
Keywords: epigenetics; integrative analysis; regulatory mechanism; multi-omics; chromatin
(This special issue belongs to the Section Molecular Genetics and Genomics)
Bonding in Supramolecular Organic Assemblies
edited by
submission deadline 30 Apr 2024 | 4 articles | Viewed by 3913
Keywords: structure-directing non-covalent interactions; supramolecular organic chemistry; molecular ensembles; molecular self-assembly
(This special issue belongs to the Section Physical Chemistry and Chemical Physics)
A Commemorative Special Issue in Honor of Prof. Dr. Luigi Fabrizio Rodella: The Founder of the Italian Society of Orofacial Pain
edited by
submission deadline 30 Apr 2024 | 2 articles | Viewed by 3804
Keywords: orofacial pain; basic pain mechanisms; management methodology; pathophysiology; neuropathic pain; neurovascular pain; burning mouth syndrome; myofascial pain
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Emerging Technologies for the Assessment and Treatment of Hemostasis (Bleeding and/or Thrombosis) Disorders
edited by
submission deadline 30 Apr 2024 | 2 articles | Viewed by 3734
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Insight into Leukemia
edited by Claire Lucas and
submission deadline 30 Apr 2024 | 2 articles | Viewed by 3603
Keywords: AML; CML; ALL; CLL; MLL; acute leukemia; chronic leukemia; myeloproliferative disorders; biomarkers; treatment; clinical outcome; treatment-free remission; bone marrow microenvironment
(This special issue belongs to the Section Molecular Oncology)
Zebrafish Model in Disease Research
edited by Niels Olsen Saraiva Camara
submission deadline 30 Apr 2024 | 3 articles | Viewed by 3464
(This special issue belongs to the Section Molecular Biology)
Advances in Molecular Biology and Treatment of Thymic Epithelial Tumors
edited by
submission deadline 30 Apr 2024 | 2 articles | Viewed by 3432
Keywords: thymic epithelial tumors; thymomas; tumor biology; pathogenesis; carcinogenesis; biomarkers; tumor microenvironment; targeted therapy; predictive markers
(This special issue belongs to the Section Molecular Oncology)
Molecular Breeding and Genetic Regulation of Crops
edited by
submission deadline 30 Apr 2024 | 5 articles | Viewed by 3403
Keywords: molecular breeding; genetic regulation; genomics; genome-editing techniques; epigenetic modifications
(This special issue belongs to the Section Molecular Plant Sciences)
Cellular and Molecular Research of Kidney Diseases 2.0
edited by
submission deadline 30 Apr 2024 | 1 articles | Viewed by 3401
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Carbohydrate, Lipid and Protein Metabolism in Human Health and Disease
edited by and
submission deadline 30 Apr 2024 | 1 articles | Viewed by 3396
Keywords: glycometabolism; lipid metabolism; amino acid metabolism; energy metabolism; metabonomics; diabetes mellitus; obesity; metabolic syndrome; dyslipidemia; inflammation; insulin resistance; nonalcoholic fatty liver
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Inflammatory Diseases, Dysbiosis and Infections submission deadline 30 Apr 2024 | 2 articles | Viewed by 3385
Keywords: microbiome; inflammation; infections; dysbiosis
(This special issue belongs to the Section Molecular Immunology)
Nutrients and Gut Microbiota-Derived Nutrients in Brain Homeostasis: From Basic Mechanisms to Diseases and Identification of Possible Therapeutic Targets
edited by
submission deadline 30 Apr 2024 | 1 articles | Viewed by 3343
Keywords: nutrients; nutrition; neurogenesis; neurodegeneration; aging; nutraceuticals; rare diseases; brain homeostasis; microbiome; gut– brain axis  
(This special issue belongs to the Section Molecular Neurobiology)
Leukemias: State-of-the-Art Molecular Pathogenesis and Influence of the Microenvironment submission deadline 30 Apr 2024 | 1 articles | Viewed by 3322
Keywords: leukemia; leukemia microenvironment; target therapy; molecular mechanisms; genetic abnormalities; gene expression
(This special issue belongs to the Section Molecular Biology)
Molecular Aspects of Endometriosis
edited by
submission deadline 30 Apr 2024 | 3 articles | Viewed by 3318
Keywords: endometriosis; molecular mechanisms; therapeutic substances; inflammatory; pathology
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Ozone Therapy in Cancer Treatment submission deadline 30 Apr 2024 | 1 articles | Viewed by 3235
Keywords: antioxidant responses; oxidative stress; gene expression; immune response; inflammation; mitochondrial activity; ozone therapy; cancer treatment; side effects; radiotherapy; chemotherapy
(This special issue belongs to the Section Molecular Oncology)
Functional Properties of Biologically Active Substances as Food Ingredients
edited by
submission deadline 30 Apr 2024 | 3 articles | Viewed by 3230
Keywords: biologically active compounds; nutritionology; Postramatuc Stress Disoder (PTSD); PTSD susceptability; oxidative stress; anti-diabiteic; anticancer properties and anti-age properties; functionality of foods; metabolic pathways of biologically active compounds
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Cancer Biology: From Genetic Aspects to Treatment
edited by
submission deadline 30 Apr 2024 | 4 articles | Viewed by 3225
Keywords: cancer biology; cancer biomarker; cancer progression; cancer metastasis; genetic of cancer
(This special issue belongs to the Section Molecular Oncology)
New Advances in B-cell Lymphoma Biology
edited by Ondrej Havranek
submission deadline 30 Apr 2024 | 2 articles | Viewed by 3146
Keywords: B-cell lymphoma; non-Hodgkin lymphoma; tumor biology; cellular signaling; lymphoma-specific genetic alterations; tumor microenvironment
(This special issue belongs to the Section Molecular Oncology)
Lithium-Ion Battery: Material Design and Mechanism Research submission deadline 30 Apr 2024 | 2 articles | Viewed by 3035
Keywords: solid electrolytes; electrode materials; interface; materials engineering; computer modeling and simulation; lithium-ion battery; lithium– sulfur battery; all-solid-state battery
(This special issue belongs to the Section Materials Science)
Molecular Pathogenesis and Diagnostics of Lung Diseases
edited by
submission deadline 30 Apr 2024 | 1 articles | Viewed by 2958
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Bioactive Compounds and Their Antioxidant Role
edited by Tamara Jurina
submission deadline 30 Apr 2024 | 3 articles | Viewed by 2620
Keywords: bioactive compounds; antioxidants; polyphenolic compounds; nutraceuticals; phytochemicals; bioavailability; medicine
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Genetic Studies of Immune-Related Diseases
edited by
submission deadline 30 Apr 2024 | 2 articles | Viewed by 2527
Keywords: autoimmune diseases; inflammatory diseases; asthma and allergies; GWAS studies; GWAS meta-analysis; eQTLs and pQTLs analysis; endophenotypes; immune cell traits; single cell transcriptomics; functional genomics; fine mapping; casual variant; drug target
(This special issue belongs to the Section Molecular Genetics and Genomics)
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