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Eye and Vision Health: Ocular Surgery, Diseases and Eyesight

A special issue of International Journal of Environmental Research and Public Health (ISSN 1660-4601). This special issue belongs to the section "Global Health".

Deadline for manuscript submissions: closed (31 July 2023) | Viewed by 5035

Special Issue Editors


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Guest Editor
Department of Ophthalmology, College of Medicine, University of Tennessee Health Science Center, Memphis, TN 38163, USA
Interests: inherited retinal dystrophies; age-related macular degeneration; glaucoma; gene therapy; inflammation
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Department of Ophthalmology, Hamilton Eye Institute, University of Tennessee Health Science Center, Memphis, TN 38163, USA
Interests: pediatric cataracts; ocular complications of children with cancer and brain tumors
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Ocular diseases are becoming more and more prevalent with time, as the predicted cases of conditions such as age-related macular degeneration and glaucoma are expected to nearly double in the next 20 years. Not only in the retina, but also the anterior segment, cases of corneal disease and damage are exceedingly common, and many surgeries target the cornea and the aqueous humor outflow structures for the treatment of both corneal and retinal disease. In addition to surgeries, novel pharmaceutical treatments and gene therapies are being developed and investigated for the treatment of many ocular diseases. It is these diseases, outcomes, and treatments that we wish to highlight in the Special Issue “Eye and Vision Health: Ocular Surgery, Diseases and Eyesight.”

This Special Issue will focus on ocular pathologies, including their etiologies and pathogeneses, how eyesight is affected in these conditions, and current and future methods of surgical, pharmaceutical, or genetic therapeutic intervention in the treatment of ocular disease.

Dr. T. J. Hollingsworth
Prof. Dr. Mary E. Hoehn
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Environmental Research and Public Health is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2500 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • ocular surgery
  • ocular pharmacotherapy
  • ocular disease
  • retinal neurodegeneration
  • anterior segment disease
  • glaucoma
  • inherited retinal dystrophy
  • age-related macular degeneration
  • ocular therapies

Published Papers (3 papers)

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Research

8 pages, 299 KiB  
Article
In a Large Healthcare System in the Bronx, Teleretinal Triaging Was Found to Increase Screening and Healthcare Access for an Underserved Population with a High Incidence of T2DM and Retinopathy
by Kevin Dahlan, Pamela Suman, David Rubaltelli, Anurag Shrivastava, Roy Chuck and Umar Mian
Int. J. Environ. Res. Public Health 2023, 20(7), 5349; https://doi.org/10.3390/ijerph20075349 - 31 Mar 2023
Cited by 1 | Viewed by 1402
Abstract
The early treatment of diabetic retinopathy (DR) prevents vision-threatening proliferative retinopathy (PDR) and macular edema (DME). Our study evaluates telemedicine (teleretinal) screening for DR in an inner-city healthcare network with a high ethnic diversity and disease burden. Fundus photographs were obtained and graded [...] Read more.
The early treatment of diabetic retinopathy (DR) prevents vision-threatening proliferative retinopathy (PDR) and macular edema (DME). Our study evaluates telemedicine (teleretinal) screening for DR in an inner-city healthcare network with a high ethnic diversity and disease burden. Fundus photographs were obtained and graded in a centralized reading center between 2014 and 2016. Patients with positive screenings were referred to a retina specialist. An analysis of sensitivity and specificity and a subgroup analysis of prevalence, disease severity, and follow-up adherence were conducted. In 2251 patients, the ‘1-year’ and ‘Overall’ follow-ups were 35.1% and 54.8%, respectively. Severe grading, male gender, and age were associated with better follow-up compliance. The DR, PDR, and DME prevalence was 24.9%, 4.1%, and 5.9%, respectively, and was significantly associated with HbA1c. The sensitivity and specificity for DR, PDR, and DME were 70% and 87%, 87% and 75%, and 37% and 95%, respectively. No prevalence differences were noted between ethnicities. Annual diabetic eye exam adherence increased from 55% to 85% during the study period. Teleretinal triaging is sensitive and specific for DR and improved diabetic eye exam compliance for underserved populations when integrated into large healthcare networks. The adherence to follow-up recommendations was better among older patients and among those with more severe retinopathy. Full article
(This article belongs to the Special Issue Eye and Vision Health: Ocular Surgery, Diseases and Eyesight)
11 pages, 641 KiB  
Article
Systemic Lupus Erythematosus and Risk of Dry Eye Disease and Corneal Surface Damage: A Population-Based Cohort Study
by Ching-Han Tseng, Ying-Hsuan Tai, Chien-Tai Hong, Ying-Xiu Dai, Tzeng-Ji Chen, Yih-Giun Cherng and Shih-Chung Lai
Int. J. Environ. Res. Public Health 2023, 20(5), 3776; https://doi.org/10.3390/ijerph20053776 - 21 Feb 2023
Cited by 2 | Viewed by 1464
Abstract
Systemic lupus erythematosus (SLE) potentially involves multiple parts of the ocular system, including the lacrimal glands and the cornea. The present study sought to assess the risk of aqueous-deficient dry eye disease (DED) and corneal surface damage in patients with SLE. We conducted [...] Read more.
Systemic lupus erythematosus (SLE) potentially involves multiple parts of the ocular system, including the lacrimal glands and the cornea. The present study sought to assess the risk of aqueous-deficient dry eye disease (DED) and corneal surface damage in patients with SLE. We conducted a population-based cohort study using Taiwan’s National Health Insurance research database to compare the risks of DED and corneal surface damage between subjects with and without SLE. Proportional hazard regression analyses were used to calculate the adjusted hazard ratio (aHR) and 95% confidence interval (CI) for the study outcomes. The propensity score matching procedure generated 5083 matched pairs with 78,817 person-years of follow-up for analyses. The incidence of DED was 31.90 and 7.66 per 1000 person-years in patients with and without SLE, respectively. After adjusting for covariates, SLE was significantly associated with DED (aHR: 3.30, 95% CI: 2.88–3.78, p < 0.0001) and secondary Sjögren’s syndrome (aHR: 9.03, 95% CI: 6.86–11.88, p < 0.0001). Subgroup analyses demonstrated that the increased risk of DED was augmented among patients with age < 65 years and female sex. In addition, patients with SLE had a higher risk of corneal surface damage (aHR: 1.81, 95% CI: 1.35–2.41, p < 0.0001) compared to control subjects, including recurrent corneal erosion (aHR: 2.98, 95% CI: 1.63–5.46, p = 0.0004) and corneal scar (aHR: 2.23, 95% CI: 1.08–4.61, p = 0.0302). In this 12-year nationwide cohort study, we found that SLE was associated with increased risks of DED and corneal surface damage. Regular ophthalmology surveillance should be considered to prevent sight-threatening sequelae among patients with SLE. Full article
(This article belongs to the Special Issue Eye and Vision Health: Ocular Surgery, Diseases and Eyesight)
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8 pages, 671 KiB  
Article
Routine Ophthalmological Examination Rates in Adults with Sickle Cell Disease Are Low and Must Be Improved
by Patricia Zulueta, Caterina P. Minniti, Anvit Rai, Tiana J. Toribio, Jee-Young Moon and Umar K. Mian
Int. J. Environ. Res. Public Health 2023, 20(4), 3451; https://doi.org/10.3390/ijerph20043451 - 16 Feb 2023
Cited by 2 | Viewed by 1674
Abstract
The American Academy of Ophthalmology and the National Heart, Lung and Blood Institute recommend patients with sickle cell disease (SCD) undergo dilated funduscopic exams (DFE) every 1–2 years to screen for sickle retinopathy. There is a paucity of data on the adherence rate [...] Read more.
The American Academy of Ophthalmology and the National Heart, Lung and Blood Institute recommend patients with sickle cell disease (SCD) undergo dilated funduscopic exams (DFE) every 1–2 years to screen for sickle retinopathy. There is a paucity of data on the adherence rate to these guidelines; a retrospective study was performed to evaluate our institution’s adherence. A chart review of 842 adults with SCD, seen 3/2017–3/2021 in the Montefiore healthcare system (All Patients), was done. Only about half of All Patients (n = 842) had >1 DFE during the study period (Total Examined Patients, n = 415). The Total Examined Patients were categorized as screening, those without retinopathy (Retinopathy−, n = 199), or follow-up, including individuals previously diagnosed with retinopathy (Retinopathy+, n = 216). Only 40.3% of screening patients (n = 87) had DFE at least biennially. As expected, there was a significant decrease in the average DFE rate of the Total Examined Patients after the COVID-19 pandemic started (13.6%) compared to pre-COVID (29.8%, p < 0.001). Similarly, there was a significant decrease in the screening rate of Retinopathy− patients from 18.6% on average pre-COVID to 6.7% during COVID (p < 0.001). This data shows the sickle retinopathy screening rate is low and innovative approaches may need to be employed to remedy this issue. Full article
(This article belongs to the Special Issue Eye and Vision Health: Ocular Surgery, Diseases and Eyesight)
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