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Diagnostics
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Imaging-Guided Techniques in Interventional Oncology
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Imaging-Guided Techniques in Interventional Oncology

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Medical Imaging and Theranostics".

Deadline for manuscript submissions: closed (31 July 2023) | Viewed by 5920

Special Issue Editor

Dr. Uei Pua

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Guest Editor
Department of Diagnostic Radiology, Tan Tock Seng Hospital, Singapore
Interests: vascular & interventional radiology

Special Issue Information

Dear Colleagues, 

Over the past decade, interventional oncology (IO) has continued to make significant strides in many areas. The initial growth had largely centered on detailing technical know-how, developing novel ideas, and ingenious problem-solving, which are hallmarks of our interventional radiology roots. While these remain key underpinnings of IO, much of the recent evolution has been in the form of deep diving into the science behind what we do, continued device development to improve consistency, safety, and outcome, and, most importantly, translating them into the standard of care through studies and rigorous data collection. In this Special Issue on “Imaging-Guided Techniques in Interventional Oncology”, you will find a series of curated articles by not just experts, but also the pacesetters and thought leaders in the various aspects of IO, spanning ablation, embolotherapy, and palliation. This Special Issue will serve as a reference for practice updates and future development.

Dr. Uei Pua
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Published Papers (4 papers)

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Research

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13 pages, 2626 KiB  
Article
Complications during CT-Guided Lung Nodule Localization: Impact of Needle Insertion Depth and Patient Characteristics
by Hua Chiang, Liang-Kuang Chen, Wen-Pei Hsieh, Yun-Xuan Tang and Chun-Yu Lo
Diagnostics 2023, 13(11), 1881; https://doi.org/10.3390/diagnostics13111881 - 27 May 2023
Cited by 1 | Viewed by 1348
Abstract
Although widely used, CT-guided lung nodule localization is associated with a significant risk of complications, including pneumothorax and pulmonary hemorrhage. This study identified potential risk factors affecting the complications associated with CT-guided lung nodule localization. Data from patients with lung nodules who underwent [...] Read more.
Although widely used, CT-guided lung nodule localization is associated with a significant risk of complications, including pneumothorax and pulmonary hemorrhage. This study identified potential risk factors affecting the complications associated with CT-guided lung nodule localization. Data from patients with lung nodules who underwent preoperative CT-guided localization with patent blue vital (PBV) dye at Shin Kong Wu Ho-Su Memorial Hospital, Taiwan, were retrospectively collected. Logistic regression analysis, the chi-square test, and the Mann–Whitney test were used to analyze the potential risk factors for procedure-related complications. We included 101 patients with a single nodule (49 with pneumothorax and 28 with pulmonary hemorrhage). The results revealed that men were more susceptible to pneumothorax during CT-guided localization (odds ratio: 2.48, p = 0.04). Both deeper needle insertion depth (odds ratio: 1.84, p = 0.02) and nodules localized in the left lung lobe (odds ratio: 4.19, p = 0.03) were associated with an increased risk of pulmonary hemorrhage during CT-guided localization. In conclusion, for patients with a single nodule, considering the needle insertion depth and patient characteristics during CT-guided localization procedures is probably important for reducing the risk of complications. Full article
(This article belongs to the Special Issue Imaging-Guided Techniques in Interventional Oncology)
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Review

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12 pages, 2295 KiB  
Review
Navigation and Robotics in Interventional Oncology: Current Status and Future Roadmap
by Georgios Charalampopoulos, Reto Bale, Dimitrios Filippiadis, Bruno C. Odisio, Bradford Wood and Luigi Solbiati
Diagnostics 2024, 14(1), 98; https://doi.org/10.3390/diagnostics14010098 - 31 Dec 2023
Cited by 1 | Viewed by 1411
Abstract
Interventional oncology (IO) is the field of Interventional Radiology that provides minimally invasive procedures under imaging guidance for the diagnosis and treatment of malignant tumors. Sophisticated devices can be utilized to increase standardization, accuracy, outcomes, and “repeatability” in performing percutaneous Interventional Oncology techniques. [...] Read more.
Interventional oncology (IO) is the field of Interventional Radiology that provides minimally invasive procedures under imaging guidance for the diagnosis and treatment of malignant tumors. Sophisticated devices can be utilized to increase standardization, accuracy, outcomes, and “repeatability” in performing percutaneous Interventional Oncology techniques. These technologies can reduce variability, reduce human error, and outperform human hand-to-eye coordination and spatial relations, thus potentially normalizing an otherwise broad diversity of IO techniques, impacting simulation, training, navigation, outcomes, and performance, as well as verification of desired minimum ablation margin or other measures of successful procedures. Stereotactic navigation and robotic systems may yield specific advantages, such as the potential to reduce procedure duration and ionizing radiation exposure during the procedure and, at the same time, increase accuracy. Enhanced accuracy, in turn, is linked to improved outcomes in many clinical scenarios. The present review focuses on the current role of percutaneous navigation systems and robotics in diagnostic and therapeutic Interventional Oncology procedures. The currently available alternatives are presented, including their potential impact on clinical practice as reflected in the peer-reviewed medical literature. A review of such data may inform wiser investment of time and resources toward the most impactful IR/IO applications of robotics and navigation to both standardize and address unmet clinical needs. Full article
(This article belongs to the Special Issue Imaging-Guided Techniques in Interventional Oncology)
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11 pages, 266 KiB  
Review
Technological Advancements in Interventional Oncology
by Alessandro Posa, Pierluigi Barbieri, Giulia Mazza, Alessandro Tanzilli, Luigi Natale, Evis Sala and Roberto Iezzi
Diagnostics 2023, 13(2), 228; https://doi.org/10.3390/diagnostics13020228 - 7 Jan 2023
Cited by 1 | Viewed by 1788
Abstract
Interventional radiology, and particularly interventional oncology, represents one of the medical subspecialties in which technological advancements and innovations play an utterly fundamental role. Artificial intelligence, consisting of big data analysis and feature extrapolation through computational algorithms for disease diagnosis and treatment response evaluation, [...] Read more.
Interventional radiology, and particularly interventional oncology, represents one of the medical subspecialties in which technological advancements and innovations play an utterly fundamental role. Artificial intelligence, consisting of big data analysis and feature extrapolation through computational algorithms for disease diagnosis and treatment response evaluation, is nowadays playing an increasingly important role in various healthcare fields and applications, from diagnosis to treatment response prediction. One of the fields which greatly benefits from artificial intelligence is interventional oncology. In addition, digital health, consisting of practical technological applications, can assist healthcare practitioners in their daily activities. This review aims to cover the most useful, established, and interesting artificial intelligence and digital health innovations and updates, to help physicians become more and more involved in their use in clinical practice, particularly in the field of interventional oncology. Full article
(This article belongs to the Special Issue Imaging-Guided Techniques in Interventional Oncology)

Other

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4 pages, 12448 KiB  
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Sequential Irreversible Electroporation for Locally Advanced Pancreatic Cancer
by Daniel Yuxuan Ong and Uei Pua
Diagnostics 2023, 13(22), 3458; https://doi.org/10.3390/diagnostics13223458 - 16 Nov 2023
Viewed by 1004
Abstract
Pancreatic cancer is a lethal disease, with locally advanced pancreatic cancer (LAPC) having a dismal prognosis. For patients with LAPC, gemcitabine-based regimens, with or without radiation, have long been the standard of care. Irreversible electroporation (IRE), a non-thermal ablative technique, may potentially prolong [...] Read more.
Pancreatic cancer is a lethal disease, with locally advanced pancreatic cancer (LAPC) having a dismal prognosis. For patients with LAPC, gemcitabine-based regimens, with or without radiation, have long been the standard of care. Irreversible electroporation (IRE), a non-thermal ablative technique, may potentially prolong the survival of patients with LAPC. In this article, the authors present a case of LAPC of the uncinate process (biopsy proven pancreatic neuroendocrine carcinoma) with duodenal invasion. The patient had a combination of chemotherapy and radiation therapy but was found to have stable disease. He then underwent intra-operative IRE with cholecystectomy, Roux-en-Y gastrojejunostomy and hepaticojejunostomy. He subsequently underwent percutaneous IRE 13 months post open IRE. The patient also completed peptide receptor radionuclide therapy and has been started on Lanreotide. Following combination therapy, the pancreatic tumor showed significant reduction in size, with patient survival at 53 months post-diagnosis at the time of writing. Full article
(This article belongs to the Special Issue Imaging-Guided Techniques in Interventional Oncology)
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