Diagnostic Imaging of Uveitis and Ocular Inflammation

Dear Colleagues, 

Since the mid-1990s, a tremendous development in intraocular imaging has taken place, and has been applied to uveitis and intraocular inflammatory diseases. After the advent of fluorescein angiography (FA) in the 1960s, which enabled the assessment of retinal inflammation, indocyanine green angiography (ICGA) followed in 1994–95, making it possible to analyze choroidal inflammation. Spectral domain optical coherence tomography (SD-OCT) then furnished quasi-histologic scans of the retina and the choroid, giving precise morphologic information of these structures. Enhanced depth imaging OCT (EDI-OCT) became available in 2008, and made it possible to measure choroidal thickness, which is a useful parameter to evaluate the severity of inflammation of choroidal stroma in stromal choroiditis, such as Vogt–Koyanagi–Harada (VKH) disease and HLA-29 birdshot retinochoroiditis. Thanks to these investigational imaging methods, it became possible to classify and understand the diverse pathological mechanisms of posterior uveitis. The novel investigative methodologies gave more precise information on some of the structures and had the advantage of being non-invasive. However, they lacked the global information obtained by invasive methods such as FA and ICGA. This opened a way to the precise appraisal and follow-up of ocular inflammatory diseases.

The aim of this project is to give a global and comprehensive approach of established and more recent imaging modalities, analyze their utility and more precisely determine the indication of these different methods. For all these aspects, authors who are experts in their field have been chosen, and more will be invited along the evolution of the project.

Suggested topics:

• Diagnostic multimodal imaging in uveitis and intraocular inflammation;
• Imaging modalities and their indications in uveitis and intraocular inflammation;
• Advantages and limitations of non-invasive imaging versus invasive imaging methods in uveitis and intraocular inflammation.

Dr. Carl P. Herbort Jr
Prof. Dr. Piergiorgio Neri
Guest Editors

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