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Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in Cancer Therapeutics

edited by

Weidong Han

and

Yubin Zhou

submission deadline 20 Sep 2024 | 16 articles | Viewed by 66479 | Submission Open

Keywords: chemotherapy; drug resistance; Immune checkpoint inhibitors (ICIs); molecular mechanisms; cancer immunotherapy; signaling pathways

(This special issue belongs to the Section Cancer Therapy)

Role of Immune Checkpoint Inhibitors or Targeted Therapy in the Treatment of Patients with Melanoma Volume II

edited by

Henrik Schmidt

and

Eva Ellebæk

submission deadline 20 Sep 2024 | 7 articles | Viewed by 14349 | Submission Open

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Microenvironment of Leukemia

edited by

Francesco Bertolini

submission deadline 20 Sep 2024 | 3 articles | Viewed by 8428 | Submission Open

Keywords: stromal microenvironment; genetic and epigenetic alterations; bone marrow; chronic and acute leukemia; hematological malignancies

(This special issue belongs to the Section Tumor Microenvironment)

Neoadjuvant Therapy of Breast Cancer

edited by

Hiroyuki Takei

and Takaaki Fujii

submission deadline 20 Sep 2024 | 5 articles | Viewed by 5854 | Submission Open

Keywords: neoadjuvant systemic therapy; chemotherapy; endocrine therapy; molecular targeted therapy; molecular subtypes; response-guided therapy; clinical trials

(This special issue belongs to the Section Cancer Therapy)

Advances in Surgery of Head and Neck Squamous Cell Carcinoma

edited by

José Angelito U. Hardillo

submission deadline 20 Sep 2024 | 4 articles | Viewed by 4503 | Submission Open

Keywords: head and neck squamous cell carcinoma; surgery; outcomes; minimally invasive techniques; precision-image-guided surgery

(This special issue belongs to the Section Cancer Therapy)

Pathogenesis, Prognosis, Prediction and Personalized Therapy in Breast Cancer

edited by Hans-Christian Kolberg

submission deadline 20 Sep 2024 | 2 articles | Viewed by 4262 | Submission Open

Keywords: breast cancer; pathogenesis; prognostic factors; predictive factors; liquid biopsy; multigene assay

(This special issue belongs to the Section Cancer Pathophysiology)

Radiochemotherapy, Radioimmunotherapy and Targeted Therapy in Locally Advanced and Metastatic Head and Neck Cancer

edited by Lianghao Ding

submission deadline 20 Sep 2024 | 1 articles | Viewed by 2668 | Submission Open

Keywords: HNSCC; radiochemotherapy; radiotherapy targeted therapy; immunotherapy; precision medicine

(This special issue belongs to the Section Cancer Therapy)

Advances in Melanoma Treatments: Molecular Targeted Therapies, Immunotherapies and Vaccines

edited by

Gagan Chhabra

Chandra Singh

and

Ichwaku Rastogi

submission deadline 20 Sep 2024 | 1 articles | Viewed by 2388 | Submission Open

Keywords: melanoma; molecular targets; DNA vaccines; RNA vaccines; peptide vaccines; virus/bacteria-based vaccines; protein vaccines; antigen-loaded cellular vaccines; immune checkpoints; immunotherapies

(This special issue belongs to the Section Cancer Therapy)

Current and Emerging Utility of Liquid Biopsy in Cancers: More than Surrogate Biomarkers (2nd Edition)

edited by

Marta Dueñas

submission deadline 20 Sep 2024 | 1 articles | Viewed by 1461 | Submission Open

Keywords: liquid biopsy; ctDNA; ctRNA; cytokine profiling; tumor biomarkers; CTC; THC

(This special issue belongs to the Section Cancer Biomarkers)

Advances in Surgical Endoscopy for Upper GI Cancers

edited by Christian Alexander Gutschow

submission deadline 20 Sep 2024 | 1 articles | Viewed by 708 | Submission Open

Keywords: endoscopy; surgery; esophagus; stomach; anastomotic leakage; early carcinoma; robotic surgery; upper GI

(This special issue belongs to the Section Methods and Technologies Development)

Study and Treatment of Oral Squamous Cell Carcinoma (Volume II)

edited by

Samer George Hakim

and Richard Yuxiong Su

submission deadline 20 Sep 2024 | Viewed by 529 | Submission Open

Keywords: oral squamous cell carcinoma (OSCC); histopathology; oral reconstruction; radiotherapy immune therapy; oral rehabilitation

(This special issue belongs to the Section Cancer Therapy)

Research Progress of Prostate Cancer Stem Cell Inhibitors

edited by

Hisham Bahmad

submission deadline 20 Sep 2024 | Viewed by 420 | Submission Open

Keywords: prostate cancer; cancer stem cells; inhibitors; biomarkers; therapeutic target; personalized medicine; targeted therapy; molecular signatures; diagnosis; prognosis

(This special issue belongs to the Section Cancer Therapy)

Interdisciplinary Approach to Soft Tissue Sarcoma Care: Bridging Gaps for Better Outcomes

edited by Juan Pretell-Mazzini

submission deadline 20 Sep 2024 | Viewed by 266 | Submission Open

Keywords: multidisciplinary treatment approach for soft tissue sarcomas; epidemiology; classification; diagnostic modalities; treatment options; survival

(This special issue belongs to the Section Cancer Therapy)

The Duality of MYB: Normal and Cancer Cell Functions

edited by

Haseeb Zubair

submission deadline 20 Sep 2024 | Viewed by 231 | Submission Open

(This special issue belongs to the Section Molecular Cancer Biology)

Recent Research on Immunotherapy in Ovarian Cancer

edited by John Stagg

submission deadline 25 Sep 2024 | 1 articles | Viewed by 5860 | Submission Open

Keywords: ovarian cancer; immunotherapy; immune checkpoint; CAR T cells; cancer vaccine; BITE; oncolytic virus

(This special issue belongs to the Section Cancer Therapy)

Advances in the Management of Pelvic Tumors

edited by

Maria Chiara Sighinolfi

and Giorgia Gaia

submission deadline 25 Sep 2024 | 3 articles | Viewed by 4222 | Submission Open

Keywords: pelvic cancer; prostate cancer; bladder cancer; uterine cancer; ovarian cancer; rectal cancer; anal cancer

(This special issue belongs to the Section Cancer Therapy)

The Computational Methods for Anticancer Drug Development

edited by

Liye He

submission deadline 25 Sep 2024 | Viewed by 668 | Submission Open

Keywords: computational methods; precision medicine; drug repositioning; deep learning; drug combinations; machine learning; targeted therapy; biomarkers; drug screening; computational toolboxes; web-based applications

(This special issue belongs to the Section Cancer Drug Development)

Hot Topics in Neuro-Oncology

edited by

Riccardo Soffietti

and

Roberta Rudà

submission deadline 27 Sep 2024 | 5 articles | Viewed by 15482 | Submission Open

Keywords: neuro-oncology; brain tumors; diagnosis; treatment; chemotherapy; targeted agents; molecular subtypes; targeted therapies; checkpoint inhibitors; immunotherapy

(This special issue belongs to the Section Cancer Therapy)

Research on Fluorescence-Guided Surgery in Cancer Treatment

edited by

Julius Höhne

submission deadline 27 Sep 2024 | Viewed by 214 | Submission Open

Keywords: fluorescence-guided surgery; fluorescent agents; tumor fluorescence; tumor margin detection; residual tumor assessment; glioma surgery; fluorescein sodium; 5-aminolevulinic acid; confocal endomicroscopy; Raman spectroscopy

(This special issue belongs to the Section Cancer Therapy)

Advances in Invasive Breast Cancer: Treatment and Prognosis

edited by

Eleni Timotheadou

and Emmanouil Saloustros

submission deadline 30 Sep 2024 | 13 articles | Viewed by 18483 | Submission Open

Keywords: ER+/HER2 – breast cancer; HER2 + breast cancer; triple-negative breast cancer; treatment toxicity and quality of life; survivorship issues

(This special issue belongs to the Section Cancer Therapy)

Pre-clinical Studies of Personalized Medicine for Cancer Research

edited by

Nuno Vale

submission deadline 30 Sep 2024 | 5 articles | Viewed by 15942 | Submission Open

Keywords: patient-derived models; genomic profiling; drug screening; biomarker validation; combination therapies; mechanistic studies; tumor heterogeneity; data analysis and interpretation

(This special issue belongs to the Section Cancer Biomarkers)

Novel Biomarkers in Non-small Cell Lung Cancer (NSCLC)

edited by

Alfredo Tartarone

submission deadline 30 Sep 2024 | 8 articles | Viewed by 14972 | Submission Open

Keywords: NSCLC; biomarkers; next-generation sequencing (NGS); liquid biopsy; immunotherapy; targeted therapies

(This special issue belongs to the Section Cancer Biomarkers)

Interplay between Signaling Pathways and Metabolism in Brain Tumors

edited by

Christina Piperi

and

Elias A. El-Habr

submission deadline 30 Sep 2024 | 5 articles | Viewed by 11920 | Submission Open

Keywords: brain tumors; intracellular signaling pathways; metabolic pathways; signaling molecules; transcription factors; genetic factors; epigenetic markers; tumor biomarkers; clinical markers; cancer therapy

(This special issue belongs to the Section Cancer Pathophysiology)

Biomarker in Urologic Cancer

edited by

Nessn H. Azawi

submission deadline 30 Sep 2024 | 7 articles | Viewed by 10609 | Submission Open

Keywords: urological cancer; biomarkers; diagnosis; prognosis; treatment response; surveillance; imaging; molecular; genetics; urine-based biomarkers

(This special issue belongs to the Section Cancer Biomarkers)

Prevention and Screening in Gynaecological Cancers

edited by

Raj Naik

Pierre Martin-Hirsch

, Evangelos Paraskevaidis and

Maria Kyrgiou

submission deadline 30 Sep 2024 | 5 articles | Viewed by 9980 | Submission Open

Keywords: cervical; uterine; endometrial; ovarian; vulvar; cancer; prevention; screening; epidemiology

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Head and Neck Cancer: Epidemiology, Prevention, Treatment, and Quality of Life

edited by

Melissa Henry

submission deadline 30 Sep 2024 | 7 articles | Viewed by 9565 | Submission Open

Keywords: head and neck cancer; epidemiology; prevention; treatment; quality of life

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Cancer Stem Cells and Targeted Therapy

edited by

Wenyi Gu

submission deadline 30 Sep 2024 | 3 articles | Viewed by 9293 | Submission Open

Keywords: tumor initiation; tumor colonization; biomarkers for cancer stem cells; signaling pathways for cancer stem cells; cancer differentiation and self-renewal; cancer therapy targeting cancer stem cells; drug delivery targeting cancer stem cells; TME targeted therapy; hypoxia targeted cancer therapy; self-renewal targeted cancer therapy

(This special issue belongs to the Section Cancer Therapy)

Existing and Emerging Biomarkers for Immune Checkpoint Immunotherapy in Solid Tumors

edited by Nuria Romero-Laorden

submission deadline 30 Sep 2024 | 6 articles | Viewed by 8839 | Submission Open

Keywords: immunotherapy; checkpoint inhibitors; biomarkers; immune biomarkers; PD-L1; TMB; solid tumors

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Rhabdomyosarcoma: Still Unresolved Questions but New Perspectives

edited by

Ewa Koscielniak

and

Monika Sparber-Sauer

submission deadline 30 Sep 2024 | 3 articles | Viewed by 7100 | Submission Open

Keywords: rhabdomyosarcoma; molecular characterization; late effects; RMS predisposition; innovative therapies

(This special issue belongs to the Section Molecular Cancer Biology)

Glioblastoma: Recent Advances and Challenges

edited by

P. Leia Nghiemphu

submission deadline 30 Sep 2024 | 3 articles | Viewed by 7075 | Submission Open

Keywords: glioblastoma; cancer immunotherapy; brain tumor microenvironment; molecular targeted therapy; GBM

(This special issue belongs to the Section Cancer Therapy)

Circadian Rhythms, Cancers and Chronotherapy

edited by

Francis Levi

Pasquale F. Innominato

and Esra Tasali

submission deadline 30 Sep 2024 | 4 articles | Viewed by 6775 | Submission Open

Keywords: circadian rhythms; clock genes; carcinogenesis; chronotherapy; biomarkers; patient-reported outcomes; sleep; sex; precision oncology; artificial intelligence

(This special issue belongs to the Section Cancer Therapy)

Quality of Life and Side Effects Management in Cancer Treatment (Volume II)

edited by

António Araújo

submission deadline 30 Sep 2024 | 6 articles | Viewed by 6705 | Submission Open

Keywords: cancer treatment adverse events; quality of life in cancer patients; chemotherapy adverse events; target therapy adverse events; immunotherapy adverse events; hormonotherapy adverse events; chemotherapy-induced nausea and vomiting; cancer pain

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Biomarkers in Prostate Cancers

edited by

Shigeo Horie

submission deadline 30 Sep 2024 | 6 articles | Viewed by 6440 | Submission Open

Keywords: PSA; androgen receptor; testosterone; DNA damage response; polygenic risk score; chromosomal aberration; telomere; MDSC

(This special issue belongs to the Section Cancer Biomarkers)

Imaging and Molecular Biology as Biomarkers for Lung Cancer

edited by

Salvatore Cappabianca

and

Umberto Malapelle

submission deadline 30 Sep 2024 | 3 articles | Viewed by 5103 | Submission Open

Keywords: radiomics; molecular biology; biomarkers; lung cancer; NSCLC; radiogenomics; precision medicine

(This special issue belongs to the Section Cancer Biomarkers)

Editorial Board Members’ Collection Series: Treatment of Pediatric Solid Tumors

edited by

Alberto Pappo

and

Godfrey Chan

submission deadline 30 Sep 2024 | 3 articles | Viewed by 4762 | Submission Open

Keywords: pediatric solid tumor; brain tumors; therapeutic strategies; immunotherapy; targeted therapy

(This special issue belongs to the Section Pediatric Oncology)

Histology and Pathology of Pancreatic Cancer

edited by Jiaqi Shi and Olca Basturk

submission deadline 30 Sep 2024 | 2 articles | Viewed by 4634 | Submission Open

Keywords: pancreatic cancer; pathology; classification; molecular mechanisms; tumor microenvironment

(This special issue belongs to the Section Cancer Pathophysiology)

Gynecologic Cancers: Clinical Research Progress of Resection

edited by Lukasz Wicherek

submission deadline 30 Sep 2024 | 3 articles | Viewed by 4303 | Submission Open

(This special issue belongs to the Section Clinical Research of Cancer)

The Role of Chromosomal Instability in Cancer

edited by

Henry H. Heng

submission deadline 30 Sep 2024 | 3 articles | Viewed by 4285 | Submission Open

Keywords: aneuploidy; cancer evolution; chromothripsis; chromosomal translocation; genome chaos; genome instability; heterogeneity; karyotype coding; polyploid giant cancer cells

(This special issue belongs to the Section Molecular Cancer Biology)

Radiotherapy for Head and Neck Squamous Cell Carcinoma

edited by Cesare Guida and Ida D'Onofrio

submission deadline 30 Sep 2024 | 4 articles | Viewed by 3915 | Submission Open

Keywords: head and neck squamous cell carcinoma; radiotherapy; biomarker; chemoradiotherapy; head and neck cancers

(This special issue belongs to the Section Cancer Therapy)

Comprehensive Genomic Profiling for Metastatic Breast Cancer: Current Status and Future Perspectives

edited by

Hiroshi Tada

and

Hiroko Masuda

submission deadline 30 Sep 2024 | 2 articles | Viewed by 3201 | Submission Open

Keywords: breast cancer; comprehensive genomic profiling; molecular matched therapy; mBC; signaling pathways

(This special issue belongs to the Section Molecular Cancer Biology)

Mechanisms of Cancer Cells Escape from Immune Surveillance: The Focus on Epigenetic and Pro-inflammatory Adaptations

edited by

Olga Sukocheva

and

Margarita Neganova

submission deadline 30 Sep 2024 | 2 articles | Viewed by 3151 | Submission Open

Keywords: immune surveillance; cancer resistance; tumor microenvironment; cancer immunoediting; epigenetic regulation; apoptosis; necroptosis; cuproptosis

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Histopathology of Urological Cancers

edited by Vikas Mehta, Antoun Toubaji and Vijayalakshmi Ananthanarayanan

submission deadline 30 Sep 2024 | 2 articles | Viewed by 2940 | Submission Open

Keywords: renal cell carcinoma; prostate; testis Ggrm cell tumors; urothelial carcinoma; artificial intelligence; ductal adenocarcinoma of prostate; neuroendocrine differentiation of prostate carcinoma; next-generation sequencing

(This special issue belongs to the Section Cancer Pathophysiology)

Targets and Biomarkers in Cutaneous Lymphoma

edited by

Chalid Assaf

and Gabor Dobos

submission deadline 30 Sep 2024 | 1 articles | Viewed by 2552 | Submission Open

Keywords: cutaneous T cell lymphoma (CTCL); biomarker; targets; diagnostics; personalized medicine; mycosis fungoides; Sé zary syndrome; genetics; epigenetics; tumor microenvironment

(This special issue belongs to the Section Cancer Biomarkers)

Recent Advances in Ovarian Cancer Surgery

edited by

Henri Azaïs

submission deadline 30 Sep 2024 | 2 articles | Viewed by 2168 | Submission Open

Keywords: epithelial ovarian cancer; hyperthermic intraperitoneal chemotherapy; minimally invasive surgery; robotic surgery; fluorescence guided surgery; lymph node dissection; enhanced recovery; photodynamic therapy

(This special issue belongs to the Section Cancer Therapy)

Neuroendocrine Tumors: Clinical and Translational Research

edited by

Erika Peverelli

and Mantovani Giovanna

submission deadline 30 Sep 2024 | 1 articles | Viewed by 1601 | Submission Open

Keywords: neuroendocrine tumors; biomarkers; intracellular signalling; somatostatin receptors; dopamine receptor type 2; pharmacological resistance

(This special issue belongs to the Section Clinical Research of Cancer)

The Role of Aromatase Inhibitors in Breast Cancer Treatment

edited by

Chandra Bhushan Mishra

submission deadline 30 Sep 2024 | 1 articles | Viewed by 1518 | Submission Open

Keywords: aromatase inhibitors; breast cancer; enzyme aromatase; estrogen

(This special issue belongs to the Section Cancer Therapy)

Disruption of Cell Signaling Pathways in Cancer: Prognostic and Treatment Perspectives

edited by Piotr M. Wierzbicki and

Irina Draga-Caruntu

submission deadline 30 Sep 2024 | 1 articles | Viewed by 1397 | Submission Open

Keywords: oncogenes; tumor suppressor genes; signaling pathways; targeted therapies; outcome; prognostic factor; cancer resistance

(This special issue belongs to the Section Cancer Therapy)

Tumor Necrosis Factor: Molecular Insights and Clinical Implications (Volume II)

edited by Lorraine A. O'Reilly

submission deadline 30 Sep 2024 | 1 articles | Viewed by 1386 | Submission Open

Keywords: TNF; cancer; cell death; inflammation; clinical; therapy; immunotherapy; biosimilars

(This special issue belongs to the Section Molecular Cancer Biology)

Obesity and Cancers

edited by Edward Sauter and Tanya Agurs-Collins

submission deadline 30 Sep 2024 | 1 articles | Viewed by 1361 | Submission Open

Keywords: obesity; cancer; mitigating factors; weight loss; weight gain; obesity interventions

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Digital Health Technologies in Oncology

edited by

Sorana D. BOLBOACĂ

submission deadline 30 Sep 2024 | 1 articles | Viewed by 1307 | Submission Open

Keywords: digital healthcare; digital health technologies; diagnosis; wearable devices; rehabilitation technologies; assistive technologies; robotic surgery; (remote) monitoring; precision medicine; data analytics; healthcare teleassistance; AI-driven diagnostics and monitoring; AI-driven analytics

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

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