Clinical Research in Cancer
A section of Cancers (ISSN 2072-6694).
Section Information
Clinical Research in Cancer is a dedicated Section of the journal Cancers that publishes high-quality, peer-reviewed clinical investigations aimed at advancing the understanding, prevention, diagnosis, and management of cancer in human populations. This Section encompasses a broad scope of clinical oncology research, including randomized and non-randomized controlled trials (Phases I–IV), prospective and retrospective observational studies, comparative effectiveness research, and registry-based or real-world evidence analyses.
The Section invites submissions addressing clinically significant questions across all tumor types and disease stages, with particular emphasis on the following:
- Clinical trials evaluating novel therapeutic strategies—including targeted agents, immunotherapies, antibody–drug conjugates, and combination regimens—with rigorous assessment of efficacy, safety, tolerability, and biomarker-informed patient stratification;
- Surgical oncology and perioperative research, including comparative effectiveness of open versus minimally invasive or robotic surgical approaches; validation of surgical quality metrics and standardized outcome measures; optimization of patient selection criteria; and integration of perioperative interventions—such as enhanced recovery pathways and multimodal supportive care—within multidisciplinary treatment frameworks;
- Translational clinical research that bridges preclinical discovery to clinical application, particularly studies elucidating pharmacogenomic determinants of drug response, mechanisms of resistance, predictive and prognostic biomarkers, and frameworks for implementing precision oncology in diverse clinical settings;
- Investigations identifying robust clinical, pathological, molecular, and imaging-based prognostic and predictive factors associated with survival, recurrence risk, treatment response, and resistance patterns.
Keywords
- clinical trials;
- surgical oncology;
- perioperative care;
- clinical outcomes;
- comparative effectiveness;
- precision medicine;
- prognosis;
- multidisciplinary care;
- real-world evidence;
- observational study;
- registry-based study;
- clinical decision-making;
- late effects;
- translational research
Editorial Board
Topical Advisory Panel
Special Issues
Following special issues within this section are currently open for submissions:
- Emergencies in Gastrointestinal Surgical Oncology (Deadline: 31 August 2026)
- Clinical Trials for T-Cell Lymphoma (Deadline: 31 August 2026)
- Clinical Outcomes in Urologic Cancers (2nd Edition) (Deadline: 31 August 2026)
- Pancreatic Cancer: Clinical Trials, Treatment Strategies, and Future Directions (Deadline: 31 August 2026)
- Clinical and Research Progress in the Resection of Gastro-Esophageal Cancer (2nd Edition) (Deadline: 31 August 2026)
- Advances in Minimally Invasive Surgery for Gastrointestinal Cancers: Laparoscopic and Robotic Approaches (Deadline: 31 August 2026)
- Acute Myeloid Leukemia in Adults (2nd Edition) (Deadline: 31 August 2026)
- Clinical Application of Proton Pencil Beam Scanning Radiotherapy in Cancer (Deadline: 31 August 2026)
- Prostatectomy Today: Surgical Advances in Prostate Cancer Management (Deadline: 1 September 2026)
- Exercise and Cancer Treatment: The Clinical Application of Exercise Oncology (Deadline: 10 September 2026)
- Onco-Nephrology: From Molecular to Clinical Studies (Deadline: 16 September 2026)
- Clinical Advances in Colorectal Cancers (Deadline: 20 September 2026)
- Clinical Outcomes in Upper GI Cancers (Deadline: 20 September 2026)
- Development of Hepatitis C Virus-Related Cancers (Deadline: 20 September 2026)
- Acute Myeloid Leukemia: Updates on Diagnosis and Novel Management Strategies (Deadline: 25 September 2026)
- Breast Cancer and Pregnancy: Clinical, Translational, and Psychosocial Perspectives (Deadline: 30 September 2026)
- Cancer Drug Resistance: Mechanisms and Overcoming Strategies (Deadline: 30 September 2026)
- Management of Orbital Tumors (Deadline: 30 September 2026)
- Clinical Trials and Translational Research in Multiple Myeloma (Deadline: 30 September 2026)
- Advances in Clinical Trials and Precision Medicine for Neuro-Oncology (Deadline: 30 September 2026)
- Hematologic Malignancies: Clinical Features and Prognostic Indicators (Deadline: 30 September 2026)
- Advances in Brain Tumors (Deadline: 30 September 2026)
- Neurosurgery Research on Brain Tumors: A Focus on Gliomas and Other Intra-Axial Brain Tumors (Deadline: 30 September 2026)
- Clinical Applications of Precision Diagnosis for Thyroid Cancers and Its Clinical Use for Treatments Choice (Deadline: 30 September 2026)
- State of the Art and Advances in Kaposi Sarcoma (Deadline: 30 September 2026)
- Robotic and Thoracoscopic Surgery for Thoracic Oncology (Deadline: 30 September 2026)
- The Role of Surgery in Lung Cancer Treatment (Deadline: 1 October 2026)
- Evolving Paradigms in Minimally Invasive and Ablative Endocrine Thyroid Surgery (Deadline: 15 October 2026)
- Pathological Features and Treatment Strategies of Head and Neck Cancer (Deadline: 15 October 2026)
- Thyroid Cancer Recurrence: Integrating Surgical, Clinical, and Translational Research (Deadline: 20 October 2026)
- Clinical Research of Brachytherapy in Cancer (Deadline: 30 October 2026)
- Innovative Therapeutics for Breast Cancer: Advancing Clinical and Translational Research (Deadline: 30 October 2026)
- The Next Generation of Prognosis: Novel Biomarkers in AML and MDS (Deadline: 31 October 2026)
- Surgical Treatment of Abdominal Tumors (Deadline: 31 October 2026)
- Clinical Research in Gynecological Cancers (Deadline: 31 October 2026)
- Advances in Skull Base Tumor Surgery: From Diagnosis to Minimally Invasive Treatment (Deadline: 31 October 2026)
- Innovations in Surgical and Management Strategies for Complex and Advanced Gastric Cancer (Deadline: 31 October 2026)
- Clinical Research in Ocular Oncology (Deadline: 31 October 2026)
- Clinical Benefit of Hybrid PET/MRI Molecular Imaging in Oncology (Deadline: 31 October 2026)
- Translational Research and Clinical Trials in Gastric Cancer: Advances and Future Directions (Deadline: 15 November 2026)
- Evaluating the Clinical Impact of Robotic Surgery in the Management of Colorectal Cancer (Deadline: 15 November 2026)
- Acute Myeloid Leukemia: Novel Therapeutic Agents and Clinical Trials (Deadline: 30 November 2026)
- Innovative Therapeutic Approaches in Acute Myeloid Leukemia (AML): Insights from Recent Clinical Trials (Deadline: 30 November 2026)
- Health Equity and Clinical Outcomes in Hepatocellular Carcinoma (Deadline: 30 November 2026)
- Redefining Breast Cancer Surgery: Emerging Technologies and De-Escalation Strategies (Deadline: 30 November 2026)
- Advancements in the Science of Endocrine Surgical Oncology (Deadline: 30 November 2026)
- Reducing the Risk of Hepatitis B-Associated Chronic Liver Disease and Hepatocellular Carcinoma (Deadline: 30 November 2026)
- Clinical Studies in Gastrointestinal Malignancies: 2nd Edition (Deadline: 30 November 2026)
- New Approaches to Surgical Treatment and Care for Urological Cancer (Deadline: 30 November 2026)
- New Clinical Insights into Gastrointestinal Cancers (Deadline: 30 November 2026)
- Clinical and Translational Research in Head and Neck Cancer—2nd Edition (Deadline: 15 December 2026)
- Stereotactic Radiosurgery for Malignant Brain Tumors (Deadline: 20 December 2026)
- Personalizing Genitourinary Cancer Care (Deadline: 30 December 2026)
- Surgical Oncology for Hepato-Pancreato-Biliary Cancer: 2nd Edition (Deadline: 31 December 2026)
- Laparoscopic and Robotic Surgery for Gastrointestinal and Hepato-Pancreato-Biliary Cancers (Deadline: 31 December 2026)
- Unveiling the Complexity of Hepato-Biliary-Pancreatic Cancers: From Pathogenesis to Management (Deadline: 31 December 2026)
- Clinical Pathology of Lung Cancer (2nd Edition) (Deadline: 31 December 2026)
- Advancements in Surgical and Multidisciplinary Management of Hepatopancreaticobiliary Cancers (Deadline: 31 December 2026)
- Classification, Risk Assessment and Clinical Management of Malignant Thyroid Nodules: 2nd Edition (Deadline: 31 December 2026)
- Real-World Clinical Studies in Acute Leukemia (Deadline: 31 December 2026)
- Advances in Clinical Therapy and Prognosis of Gastrointestinal Cancer (Deadline: 30 January 2027)
- Clinical Trials and Outcomes for Non-Small Cell Lung Cancer (Deadline: 31 January 2027)
- Laryngeal Cancer: Diagnostic Workup, Treatment, and Complications (Deadline: 31 January 2027)
- Resection and Reconstruction for Breast Cancer (Deadline: 31 January 2027)
- Precision Medicine and Targeted Therapies in Neuroblastoma (Deadline: 31 January 2027)
- Clinical Trials for Hepatobiliary and Pancreatic Cancer Diagnosis and Treatment (2nd Edition) (Deadline: 31 January 2027)
- Thoracic Surgical Oncology—Current Landscape and Future Directions (Deadline: 31 January 2027)
- Pancreaticoduodenectomy in the Treatment of Pancreatic Cancer (Deadline: 15 February 2027)
- Progress and Perspectives of Organoid Technology in Precision Oncology (Deadline: 28 February 2027)
- Research on Clinical Treatment of Mesothelioma: 2nd Edition (Deadline: 28 February 2027)
- Minimally Invasive and Innovative Approaches in Breast Cancer Surgery: Techniques and Outcomes (Deadline: 28 February 2027)
- Clinical Treatment and Prognosis of Breast Cancer (Deadline: 31 March 2027)
- Current Advances in Surgical and Systemic Treatment of Breast Cancer (Deadline: 31 March 2027)
- Multidisciplinary Strategies in Challenging Neuro-Oncological Surgery (Deadline: 31 March 2027)
- Advances in Musculoskeletal Oncology (Deadline: 31 March 2027)
- Innovative Clinical Trial Designs Shaping the Future of Cancer Research (Deadline: 31 March 2027)
- Rare Genitourinary Cancers (Deadline: 15 April 2027)
- Surgery and Clinical Outcomes in Head and Neck Squamous Cell Carcinoma (Deadline: 29 April 2027)
- Clinical Treatment and Outcomes of Gastrointestinal Cancer (Deadline: 30 April 2027)
- The Clinical Trials and Management of Acute Myeloid Leukemia: 2nd Edition (Deadline: 14 May 2027)
- Clinical Studies of Colorectal Cancer Surgery (Deadline: 25 May 2027)
- Liver Transplantation Oncology: Innovations, Multidisciplinary Management, and Evolving Clinical Strategies (Deadline: 31 May 2027)
- Recent Advances in Thyroid Cancer and Thyroid Cancer Surgery (Deadline: 30 June 2027)
- Recent Advances and Future Perspectives in Neurosurgical Oncology (Deadline: 31 July 2027)
Topical Collections
Following topical collections within this section are currently open for submissions: