Special Issues

Biomolecules publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic. The journal’s Editor-in-Chief and/or designated EBM will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Conventional and In Silico-Based Approaches for the Optimization of Nanobody Biophysical Characteristics
edited by
submission deadline 15 Jul 2024 | Viewed by 91 | Submission Open
Keywords: nanobodies; modeling; screening strategies; random mutagenesis; rational engineering; expression conditions
PARPs in Cell Death and PARP Inhibitors in Cancers submission deadline 20 Jul 2024 | 1 articles | Viewed by 2018 | Submission Open
Keywords: PARPs; PARP inhibitors; cancers; cell death; DNA repair
(This special issue belongs to the Section Molecular Medicine)
Advances in tRNA Biology
edited by
submission deadline 20 Jul 2024 | 1 articles | Viewed by 1642 | Submission Open
(This special issue belongs to the Section Biomacromolecules: Nucleic Acids)
Human Epidermal Stem Cells: Molecular Identifiers and Functional Regulators submission deadline 20 Jul 2024 | Viewed by 186 | Submission Open
Keywords: human epidermis; stem cells; intrinsic characters; dialogues; exposome
(This special issue belongs to the Section Molecular Biology)
Genetics and Genomics of Leukaemia
edited by and
submission deadline 23 Jul 2024 | Viewed by 538 | Submission Open
Keywords: leukaemia; blood; genetics; genomics; chromosome
(This special issue belongs to the Section Molecular Genetics)
Unraveling the Complexity of the Human Spliceosome and RNA Splicing
edited by Liliana Florea
submission deadline 30 Jul 2024 | Viewed by 173 | Submission Open
Keywords: spliceosome; splicing regulation; RNA splicing in human physiology and development; computational modelling
(This special issue belongs to the Section Biomacromolecules: Nucleic Acids)
Stress, Aging and Metabolism
edited by
submission deadline 31 Jul 2024 | 3 articles | Viewed by 8783 | Submission Open
Keywords: DNA damage; oxidative stress; aging; lifespan; healthspan; metabolism; stress-induced molecules and their functions; autophagy; exercise; nutritional restriction
(This special issue belongs to the Section Molecular Medicine)
The Role of Tumor Microenvironment in the Pathogenesis and Progression of Hematological Malignancies
edited by
submission deadline 31 Jul 2024 | 3 articles | Viewed by 6227 | Submission Open
Keywords: inflammation; metabolic rewiring; epigenetics; mesenchymal stromal cells; immune cells; immune-escape
(This special issue belongs to the Section Molecular Medicine)
Defects in the Transport Mechanism of Membrane Proteins and Related Diseases submission deadline 31 Jul 2024 | 3 articles | Viewed by 5668 | Submission Open
Keywords: function; structure and folding of membrane transport proteins; pathological mutations; mechanism of transport; neurological and metabolic disease; transport of nanoparticles; organelle membranes; cellular function and signaling; bioenergetics; neuroinflammation; nanoformulations for drug targets
(This special issue belongs to the Section Cellular Biochemistry)
Molecular Research in Uterine Physiology and Pathology submission deadline 31 Jul 2024 | 3 articles | Viewed by 4502 | Submission Open
Keywords: endometrium; myometrium; endometriosis; uterine disorders; uterine molecular alterations; reproduction; implantation; endometrial cancer; uterine fluid; adenomyosis; leiomyoma; endometritis
(This special issue belongs to the Section Molecular Medicine)
NMDA Receptor in Health and Diseases 2.0
edited by
submission deadline 31 Jul 2024 | 3 articles | Viewed by 4421 | Submission Open
(This special issue belongs to the Section Molecular Biology)
The Value of Natural Compounds as Therapeutic Agents II submission deadline 31 Jul 2024 | 3 articles | Viewed by 3648 | Submission Open
Keywords: natural compound; acute and chronic conditions; cell proliferation; cell death; cell differentiation
(This special issue belongs to the Section Natural and Bio-inspired Molecules)
Mitochondrial Proteins: From Import and Biogenesis to Complex Functional Network submission deadline 31 Jul 2024 | 1 articles | Viewed by 3436 | Submission Open
Keywords: mitochondrial proteins; import; biogenesis; metabolism; functional network; oxidative stress; small molecules; mitochondrial protein quality control; mitophagy
(This special issue belongs to the Section Biomacromolecules: Proteins)
H2S, Polysulfides, and Enzymes: Physiological and Pathological Aspects 2.0 submission deadline 31 Jul 2024 | 2 articles | Viewed by 3337 | Submission Open
Keywords: H2S  and polysulfide; H2S  in inflammation; H2S  in brain; heart; liver; kidney; and pulmonary diseases; H2S  in cancer cells; H2S  in the pathogenesis of diabetes; H2S  and polysulfides biosynthetic enzymes; H2S  precursors
(This special issue belongs to the Section Molecular Medicine)
Biomarkers in Renal Diseases Ⅱ submission deadline 31 Jul 2024 | 2 articles | Viewed by 3193 | Submission Open
Keywords: biomarkers; acute kidney injury; chronic kidney disease; microvesicles; exosomes
(This special issue belongs to the Section Molecular Biomarkers)
Prostate Cancer Biomarkers and Therapeutics
edited by Kamlesh Kumar Yadav
submission deadline 31 Jul 2024 | 2 articles | Viewed by 2743 | Submission Open
Keywords: prostate cancer; biomarkers; therapeutics; chemotherapy; immunotherapy; radiation therapy; machine learning
(This special issue belongs to the Section Molecular Biomarkers)
Advanced Glycation End-Products (AGEs): Receptors, Signalling Pathways, and Anti-AGE Therapies
edited by Maria Koziołkiewicz and Aleksandra Twarda-Clapa
submission deadline 31 Jul 2024 | 2 articles | Viewed by 2694 | Submission Open
Keywords: advanced glycation end-products; AGEs; AGE receptors; anti-AGE therapies; RAGE; scavenger receptors; AGE-related diseases; signalling pathways
(This special issue belongs to the Section Biomacromolecules: Carbohydrates)
Molecular Aspects of Diseases Origin and Development
edited by Natalia Kurhaluk
submission deadline 31 Jul 2024 | 1 articles | Viewed by 1683 | Submission Open
The Genomics Era: From Reference Genomes to Pan-Genomic Approach II
edited by
submission deadline 31 Jul 2024 | 1 articles | Viewed by 1068 | Submission Open
Keywords: pangenome; genome evolution; graph-based pangenome; core and dispensable genomes; human genomics; metagenomics; transcriptome; structural variation
(This special issue belongs to the Section Molecular Genetics)
Emerging Biomarkers Discovery for Molecular Diagnostics
edited by , Masaki Shimizu and
submission deadline 31 Jul 2024 | 1 articles | Viewed by 995 | Submission Open
Keywords: emerging biomarkers; pre-clinical; molecular diagnostics; deep sequencing; omics; personalized medicine; precision medicine; targeted therapy; prognosis
(This special issue belongs to the Section Molecular Biomarkers)
Esophageal Diseases: Molecular Basis and Therapeutic Approaches
edited by and Amanda B. Muir
submission deadline 31 Jul 2024 | 1 articles | Viewed by 868 | Submission Open
(This special issue belongs to the Section Molecular Medicine)
Recent Advances in the Isolation, Chemical and Biological Characterization and Synthesis of Bioactive Metabolites from Plants submission deadline 31 Jul 2024 | 1 articles | Viewed by 804 | Submission Open
Keywords: plants; bioactive metabolite; natural analogues; chemical and biological characterization; synthesis; synthetic intermediates and derivatives
(This special issue belongs to the Section Natural and Bio-inspired Molecules)
Selected Papers from the 3rd International Electronic Conference on Biomolecules submission deadline 31 Jul 2024 | Viewed by 693 | Submission Open
New Insights into Diseases with Cognitive Impairment: Development, Genesis, and Treatment
edited by
submission deadline 31 Jul 2024 | Viewed by 236 | Submission Open
Keywords: dementia; brain; biomarkers
Natural Products in Chemo- or Hormone Therapy Volume II
edited by
submission deadline 31 Jul 2024 | Viewed by 201 | Submission Open
Keywords: natural compounds; chemotherapy; hormone therapy; cancer; phytochemicals; combination
(This special issue belongs to the Section Natural and Bio-inspired Molecules)
State-of-the-Art Protein X-ray Crystallography
edited by Wu-Pei Su and
submission deadline 31 Jul 2024 | Viewed by 159 | Submission Open
Keywords: ab initio phasing methods; X-ray crystallography; protein structural determination; image reconstruction from Fourier amplitudes; iterative projection algorithms; phasing with deep learning methods
(This special issue belongs to the Section Molecular Structure and Dynamics)
Proteomics in Cancer: Current Research and Future Outlook
edited by Cinzia Franchin
submission deadline 31 Jul 2024 | Viewed by 150 | Submission Open
(This special issue belongs to the Section Biomacromolecules: Proteins)
The Role of Oxidative Stress in Ovarian Cancer submission deadline 31 Jul 2024 | Viewed by 143 | Submission Open
Keywords: ovarian cancer; reactive oxygen species (ROS); metastasis; antioxidant; oxidative stress; chemotherapeutic resistance; inflammation
(This special issue belongs to the Section Molecular Medicine)
Advances in Cancer and Glycosylation
edited by
submission deadline 31 Jul 2024 | Viewed by 133 | Submission Open
Keywords: glycosylation; glycobiology; N-glycans; O-glycans; glycosyltransferases; glycosidases
(This special issue belongs to the Section Molecular Medicine)
Melanin-Related Biomolecules: Synthesis, Properties and Applications
edited by Kazumasa Wakamatsu and
submission deadline 31 Jul 2024 | Viewed by 128 | Submission Open
Keywords: melanin; skin aging; hair color; photoaging; antioxidant action; UV protection; cosmetology; display technology; food industry
(This special issue belongs to the Section Molecular Biology)
Role of the Immune System in Mycobacterial Infection
edited by Auriol Purdie
submission deadline 31 Jul 2024 | Viewed by 123 | Submission Open
Keywords: mycobacterial infections; host immune response; livestock species; zoonotic transmission; cross-species dynamics; macrophages; dendritic cells; T lymphocytes; pro-inflammatory signals; anti-inflammatory signals; immunomodulation; host genetic factors; veterinary immunology; animal health; tuberculosis in livestock; Johne’ s disease (Mycobacterium avium subsp. paratuberculosis); bovine tuberculosis (Mycobacterium bovis); avian tuberculosis (Mycobacterium avium); immune evasion mechanisms; comparative immunology; innate immunity; adaptive immunity; one health approach
Neurocognitive Disorders: From Molecular Mechanisms to Therapeutic Strategies
edited by Mbemba Jabbi
submission deadline 31 Jul 2024 | Viewed by 99 | Submission Open
Keywords: neurocognition; molecular mechanisms; brain anatomy; disease
(This special issue belongs to the Section Molecular Medicine)
Role of the ABI1 Gene in Cancers
edited by Leszek Kotula
submission deadline 31 Jul 2024 | Viewed by 78 | Submission Open
Keywords: ABI1 cancer EMT cell signaling actin cytoskeleton 
(This special issue belongs to the Section Molecular Genetics)
Molecular Mechanisms and Biomedical Applications of Virus Entry
edited by
submission deadline 31 Jul 2024 | Viewed by 72 | Submission Open
Keywords: heparan sulfate; virus entry; virus– host cell interactions; virus cell-to-cell fusion
Molecular Mechanisms of Drug Resistance in Breast Cancer
edited by
submission deadline 1 Aug 2024 | Viewed by 152 | Submission Open
Keywords: breast cancer; mechanism of resistance; targeted therapy resistance; ER+; HER2; TNBC; tumor microenvironment; recurrence; metastasis; tumor evasion
(This special issue belongs to the Section Molecular Medicine)
DNA Methylation in Human Diseases submission deadline 15 Aug 2024 | 4 articles | Viewed by 5050 | Submission Open
Keywords: DNA methylation alterations; DNA methylation profiling; DNMT aberrations; TET aberrations; DNA methylation machinery; DNA methylation biomarkers; DNA methylation reprogramming
(This special issue belongs to the Section Biomacromolecules: Nucleic Acids)
Extracellular Vesicles as Biomarkers of Diseases submission deadline 15 Aug 2024 | 3 articles | Viewed by 4179 | Submission Open
Keywords: extracellular vesicles; metabolic syndrome; cancer; cardiovascular diseases; neurodegenerative diseases; biomarkers
(This special issue belongs to the Section Molecular Biomarkers)
What Is the Weight of Epigenetic Inheritance over Generations? submission deadline 15 Aug 2024 | 2 articles | Viewed by 3363 | Submission Open
Keywords: genetic; epigenetic; transcripts variation; diseases; model organisms
(This special issue belongs to the Section Molecular Genetics)
The Role of Metals Ions in Neurodegenerative Diseases
edited by Imre Sòvágó
submission deadline 15 Aug 2024 | Viewed by 187 | Submission Open
Keywords: Alzheimer’ s disease; Parkinson’ s disease; metal complexes; amyloid-beta; peptide fragments of prion and tau proteins
The Role of Scaffold Proteins in Human Diseases
edited by László Buday and
submission deadline 15 Aug 2024 | Viewed by 107 | Submission Open
Keywords: scaffold proteins; cellular signalling; protein– protein interactions; protein domains; human diseases; drug targets; protein complex formation; pathogenic alterations
Advances in Melanoma Targeted Therapy
edited by
submission deadline 20 Aug 2024 | 2 articles | Viewed by 4155 | Submission Open
Keywords: melanoma; drug discovery; new targets; target discovery
(This special issue belongs to the Section Molecular Medicine)
Advances in the Molecular Mechanisms of Inflammatory Arthritis and Inflammation-Related Bone Changes submission deadline 20 Aug 2024 | 2 articles | Viewed by 2626 | Submission Open
Keywords: inflammatory arthritis; molecular mechanisms; bone changes; osteoimmunology; autoimmunity
(This special issue belongs to the Section Molecular Medicine)
Tryptophan-Kynurenine Pathway in Health and Disease submission deadline 20 Aug 2024 | Viewed by 240 | Submission Open
Keywords: tryptophan; kynurenine pathway; kynurenic acid; neuropsychiatric disorders; metabolic disorders
(This special issue belongs to the Section Molecular Medicine)
Biotechnological and Biomedical Applications of Enzymes Involved in the Synthesis of Nucleosides and Nucleotides—Volume II submission deadline 20 Aug 2024 | Viewed by 99 | Submission Open
Keywords: biotransformations; biomedicine; enzyme technology; biochemistry; organic chemistry
(This special issue belongs to the Section Enzymology)
Role of Thiols in Oxidant-Induced Injuries
edited by
submission deadline 25 Aug 2024 | Viewed by 198 | Submission Open
Keywords: cysteine; sulfhydryl; thiol; antioxidants; reactive oxygen species; free radicals; oxidant-induced injuries
(This special issue belongs to the Section Molecular Biology)
The Role of Microglia in Aging and Neurodegenerative Disease
edited by
submission deadline 25 Aug 2024 | Viewed by 188 | Submission Open
Keywords: microglia; neurodegenerative diseases; disease-associated  microglia (DAM); microglia activation; Alzheimer's disease; Parkinson’ s disease; ischemic stroke
(This special issue belongs to the Section Molecular Medicine)
Plant Polyphenols in the Immune and Inflammatory Responses - Volume II
edited by
submission deadline 25 Aug 2024 | Viewed by 178 | Submission Open
Keywords: plant polyphenol; bioactivity; immunity; inflammation; molecular mechanism; structure-function relationship
(This special issue belongs to the Section Natural and Bio-inspired Molecules)
Wnt Pathway Regulation in Development, Stem Cells and Cancer
edited by Marc De La Roche
submission deadline 25 Aug 2024 | Viewed by 178 | Submission Open
Keywords: Wnt pathway regulation and function; metazoan development; stem cells; Wnt pathway driven cancer
(This special issue belongs to the Section Biological Factors)
Connexins, Pannexins, and Homologous Channel-Forming Proteins submission deadline 30 Aug 2024 | 2 articles | Viewed by 3080 | Submission Open
Keywords: gap junctions; hemichannels; connexins; pannexins; innexins; unnexins; paracrine; autocrine
(This special issue belongs to the Section Biomacromolecules: Proteins)
Non-coding RNAs in Human Diseases: Roles and Mechanisms of Action
edited by Lei Jin
submission deadline 30 Aug 2024 | Viewed by 238 | Submission Open
Keywords: non-coding RNAs; human diseases; diagnostic markers; therapeutic targets; prognostic indicators
(This special issue belongs to the Section Molecular Genetics)
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