Special Issues

Antioxidants publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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NADPH Oxidases (NOXs)
edited by David W. Stepp
submission deadline 10 Nov 2025 | 8 articles | Viewed by 14542 | Submission Open
Keywords: NADPH oxidases; reactive oxygen species; redox signaling; cardiovascular diseases
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Roles of NADPH Oxidase in Modulation of Signal Transduction and Cellular Metabolism—2nd Edition submission deadline 10 Nov 2025 | 3 articles | Viewed by 6470 | Submission Open
Keywords: redox signaling; inflammation; NADPH oxidase; ROS; cell metabolism; redox-state; Warburg effect; metabolic reprogramming; tumor microenvironment; cell proliferation
(This special issue belongs to the Section Antioxidant Enzyme Systems)
Oxidative Stress and NRF2 in Health and Disease—2nd Edition
edited by
submission deadline 20 Nov 2025 | 9 articles | Viewed by 17436 | Submission Open
Keywords: oxidative stress; redox signaling; NRF2 and its regulation; redox-modifying therapeutic approach; omics approach; physiology; non-communicable diseases; metabolism; aging
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Alcohol-Induced Oxidative Stress in Health and Disease, 2nd Edition
edited by
submission deadline 20 Nov 2025 | 3 articles | Viewed by 4363 | Submission Open
Keywords: alcohol; alcohol use disorder; reactive oxygen species; antioxidant defense
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Oxidative Stress in Hepatic Diseases
edited by
submission deadline 21 Nov 2025 | 3 articles | Viewed by 5620 | Submission Open
Keywords: oxidative stress; hepatic diseases; liver fibrosis; reactive oxygen species (ROS); mitochondrial dysfunction; lipid peroxidation; antioxidant defense; non-alcoholic fatty liver disease (NAFLD); alcoholic liver disease; hepatoprotective strategies
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Antioxidants from Food and Food Wastes for Nutraceutical, Pharmaceutical and Cosmetic Fields
edited by Monica Locatelli and
submission deadline 25 Nov 2025 | 8 articles | Viewed by 16508 | Submission Open
Keywords: phenolic compounds; analytical methods; bioactivities; green extraction; functional ingredients; food supplements; by-products and up-cycled ingredients; nutraceutical; cosmetics; bioaccessibility
(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)
Antioxidant Compounds and Health Benefits of Mediterranean Functional Food
edited by
submission deadline 25 Nov 2025 | 2 articles | Viewed by 3865 | Submission Open
Keywords: antioxidants; anti-inflammatory; anti-obesity; functional food; human health; Mediterranean diet; nutraceuticals; nutrition; oxidative stress; phytochemicals; polyphenols
(This special issue belongs to the Section Natural and Synthetic Antioxidants)
Oxidative Stress in Animal Reproduction and Nutrition
edited by and
submission deadline 28 Nov 2025 | 4 articles | Viewed by 3719 | Submission Open
Keywords: oxidative stress; antioxidants; animal reproduction; nutritional regulation; livestock and poultry; mouse or rat model; antioxidant mechanisms; oxidative stress mechanisms
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Antioxidants in Meat and Meat Products submission deadline 28 Nov 2025 | Viewed by 233 | Submission Open
Keywords: natural antioxidants; oxidative degradation; meat shelf-life; food quality; functional food; bioactive compounds; antioxidant active packaging
(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)
Antioxidants and Retinal Diseases—2nd Edition
edited by and Jorge M. Barcia
submission deadline 30 Nov 2025 | 8 articles | Viewed by 30340 | Submission Open
Keywords: retinal diseases; antioxidants; oxygen species; extracellular vesicles; miRNA
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Antioxidant Therapy for Obesity-Related Diseases submission deadline 30 Nov 2025 | 8 articles | Viewed by 17896 | Submission Open
Keywords: obesity; inflammation; oxidative stress; organ damage; natural antioxidants; synthetic antioxidants; mechanisms of action; therapeutical approaches
(This special issue belongs to the Section Natural and Synthetic Antioxidants)
Natural Products: Biological, Antioxidant Properties and Health Effects—4th Edition
edited by
submission deadline 30 Nov 2025 | 9 articles | Viewed by 15577 | Submission Open
Keywords: algal antioxidants; agricultural by-products; algae; bioactive compounds; cancer; cardiovascular diseases; essential oils; inflammatory diseases; marine organisms; metabolic diseases; oxidative stress; phytochemicals; polyphenols; radical scavenging; shelf life; waste products
(This special issue belongs to the Section Natural and Synthetic Antioxidants)
Free Radicals, Antioxidants, and Oxidative Stress in Aging and Age-Related Diseases—2nd Edition submission deadline 30 Nov 2025 | 5 articles | Viewed by 14982 | Submission Open
Keywords: aging; oxidative stress; age-related diseases
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Oxidative Stress-Related Mechanisms and Antioxidant Therapy in Cancer submission deadline 30 Nov 2025 | 4 articles | Viewed by 13113 | Submission Open
Keywords: ascorbate; vitamin C; cancer therapy; cancer prevention; antioxidants; prooxidants; oxidative stress; epigenetic activity
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Novel Antioxidants for Animal Nutrition—2nd Edition submission deadline 30 Nov 2025 | 6 articles | Viewed by 11598 | Submission Open
Keywords: nutrition; functional diets; innovative antioxidants; feed additives; natural extracts; disease prevention; oxidative stress; one health
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Oxidative Stress in Eye Diseases submission deadline 30 Nov 2025 | 5 articles | Viewed by 9003 | Submission Open
Keywords: oxidative stress; antioxidants; reactive oxygen species; redox signaling; inflammatory cell death; age-related blinding diseases; glaucoma; cataract; age-related macular degeneration; gene regulation; retinal disorder; dry eye disorder; corneal diseases
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Inhibition of Oxidative Stress and Related Signaling Pathways in Neuroprotection—2nd Edition submission deadline 30 Nov 2025 | 5 articles | Viewed by 8985 | Submission Open
Keywords: neuroprotection; neurotoxicity; antioxidative vs. proxidative; oxidative stress; signaling pathways; redox metals
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Reactive Oxygen and Nitrogen Species in Plants―2nd Edition submission deadline 30 Nov 2025 | 4 articles | Viewed by 7741 | Submission Open
Keywords: antioxidants; hydrogen peroxide; nitric oxide; nitro-oxidative stress; ROS; RNS; hydrogen sulfide; melatonin
(This special issue belongs to the Section ROS, RNS and RSS)
The Interaction Between Gut Microbiota and Host Oxidative Stress
edited by
submission deadline 30 Nov 2025 | 3 articles | Viewed by 6668 | Submission Open
Keywords: oxidative stress; antioxidants; gut microbiome; immunity
Innovative Technologies for Detecting Antioxidant Properties and Oxidative Stabilization of Agri-Food Products and Plant Extracts
edited by
submission deadline 30 Nov 2025 | 3 articles | Viewed by 6267 | Submission Open
Keywords: green extraction; plant extracts; bioactive compounds; flavonoids; polyphenols; detection technologies; antioxidant activity
(This special issue belongs to the Section Methods for Antioxidants Evaluation/Measurement)
Developmental Origins of Health and Disease: Antioxidants as Strategy for Prevention and Treatment submission deadline 30 Nov 2025 | 4 articles | Viewed by 6253 | Submission Open
Keywords: oxidative stress; pregnancy; germline damage; obstetric complications; fetal programming
Glutathione and Health: From Development to Disease
edited by and Vasilis K. Vasiliou
submission deadline 30 Nov 2025 | 3 articles | Viewed by 5105 | Submission Open
Keywords: glutathione; antioxidants; antioxidant enzymes; oxidative stress; redox biology; molecular biology; cellular biology; biochemistry; development; disease
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Oxidative Stress and Inflammation in Neurologic Diseases
edited by
submission deadline 30 Nov 2025 | 2 articles | Viewed by 4085 | Submission Open
Keywords: oxidative stress; nitrosative stress; neuroinflammation; neurodegeneration; neuronal apoptosis
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Oxidative Stress and Antioxidants in Hypoxia and Human Pathophysiology Settings, 2nd Edition
edited by and Alejandro Gonzalez-Candia
submission deadline 30 Nov 2025 | 2 articles | Viewed by 3786 | Submission Open
Keywords: tissue hypoxia; reperfusion injury; hypoxic preconditioning; oxidative stress; antioxidants; hypoxic programing; microRNA; clinical hypoxic settings
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Natural Antioxidants from Plant-Based By-Products: Mechanisms and Applications in Food Systems submission deadline 30 Nov 2025 | 4 articles | Viewed by 3358 | Submission Open
Keywords: natural antioxidants; plant-based by-products; phenolic compounds; food preservation; shelf life extension; sustainable food systems; extraction techniques
(This special issue belongs to the Section Natural and Synthetic Antioxidants)
Oxidative Stress in Cell Senescence
edited by
submission deadline 30 Nov 2025 | 1 articles | Viewed by 3051 | Submission Open
Keywords: stem cells; cell senescence; regenerative medicine; antioxidant strategies; age-related diseases
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Redox Signaling in Cancer: Mechanisms and Therapeutic Opportunities
edited by
submission deadline 30 Nov 2025 | 2 articles | Viewed by 2407 | Submission Open
Keywords: oxidative stress; cancer; reactive oxygen species (ROS); redox signaling; natural compounds; ferroptosis
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Oxidative Stress in Plant Stress and Plant Physiology
edited by
submission deadline 30 Nov 2025 | 3 articles | Viewed by 2281 | Submission Open
Keywords: ROS signaling; stress adaptive responses; halophyte vs glycophyte; redox homeostasis; molecular crosstalk with  ROS signaling; biotic; abiotic; soil borne; and air pollutants
(This special issue belongs to the Section ROS, RNS and RSS)
Inflammation and Oxidative Stress in Articular Cartilage submission deadline 30 Nov 2025 | 2 articles | Viewed by 1812 | Submission Open
Keywords: cartilage; chondrocyte; joint inflammation; arthritis
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Hydrogen Sulfide, Reactive Sulfur Species, and Donor Compounds: Natural and Synthetic Tools for Physiology and Disease submission deadline 30 Nov 2025 | 1 articles | Viewed by 1336 | Submission Open
Keywords: hydrogen sulfide; H2S donors; H2S hybrid compounds; H2S sources; pharmacological tools; H2S signaling
Berry Antioxidants in Health and Disease—2nd Edition submission deadline 30 Nov 2025 | 1 articles | Viewed by 789 | Submission Open
Keywords: berries; antioxidants; polyphenols; berry metabolites; oxidative stress; chronic diseases; cardiovascular disease; metabolic syndrome; diabetes mellitus; cancer; neurodegenerative disease; gut microbiome
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Bioactive Antioxidants: Structural Characterization, Synthetic Pathways, and Clinical Applications
edited by
submission deadline 30 Nov 2025 | 1 articles | Viewed by 663 | Submission Open
Keywords: bioactive antioxidants; therapeutic potential; synthetic strategies; structural characterization
(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)
Oxidative Metabolism and Mitochondrial Dysfunction in Metabolic Diseases—3rd Edition submission deadline 30 Nov 2025 | Viewed by 259 | Submission Open
Keywords: mitochondria function; oxidative processes; metabolic diseases; reactive oxygen species; therapeutic approaches; mitochondrial integrity; energy production; mitochondrial bioenergetic; metabolism; mitochondrial dynamic
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Natural Products to Mitigate Oxidative Stress and Inflammation in Non-Communicable Intestinal Diseases submission deadline 30 Nov 2025 | Viewed by 219 | Submission Open
Keywords: natural bioactives; phytochemicals; oxidative stress; inflammation; non-communicable intestinal diseases; colorectal cancer; inflammatory bowel diseases; signalling pathways
Advances in Mitochondrial Redox Biology—Second Edition
edited by
submission deadline 30 Nov 2025 | Viewed by 218 | Submission Open
Keywords: mitochondria; redox signaling; reactive oxygen species (ROS); mitochondrial dynamics; bioenergetics; mitochondria– nuclear communication; aging; cell metabolism
Oxidative Stress in Pregnant Women and Fetuses submission deadline 30 Nov 2025 | Viewed by 210 | Submission Open
Keywords: metabolic programming; oxidative stress; antioxidants; mitochondria; inflammatory signaling; reactive oxygen species; reactive nitrogen species; placenta; trace elements; nutrition; gestation; offspring; pregnancy; breastfeeding; fetus
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
The Role of Oxidative Stress in Age-Related and Degenerative Eye Diseases
edited by
submission deadline 30 Nov 2025 | Viewed by 200 | Submission Open
Keywords: oxidative stress; age-related macular degeneration; retinal degeneration; reactive oxygen species; redox signaling; mitochondrial dysfunction; antioxidant therapy; artificial intelligence; multi-omics; biomarkers; vision science
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Lipid Peroxidation, Vegetable Oil Oxidation, and the Role of Plant Extracts in Enhancing Oxidative Stability
edited by and
submission deadline 30 Nov 2025 | Viewed by 187 | Submission Open
Keywords: oil oxidative stability; natural antioxidants; lipid peroxidation; surfactants; encapsulation
(This special issue belongs to the Section Aberrant Oxidation of Biomolecules)
Methodologies for Improving Antioxidant Properties and Absorption, 2nd Edition
edited by
submission deadline 30 Nov 2025 | Viewed by 170 | Submission Open
Keywords: bioavailability; targeted absorption; delivery systems; antioxidant structural modification; structure– activity relationship
(This special issue belongs to the Section Natural and Synthetic Antioxidants)
Artificial Intelligence and Other Bioinformatic Modern Technologies Approaches to the Study of Antioxidant Capacity in Food Production
edited by
submission deadline 5 Dec 2025 | Viewed by 509 | Submission Open
Keywords: artificial intelligence; bioinformatics; food processing; food quality; antioxidant capacity; big data
(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)
The Role of Oxidative Stress in Environmental Toxicity—2nd Edition
edited by Hariz Islas Flores
submission deadline 10 Dec 2025 | 1 articles | Viewed by 1462 | Submission Open
Keywords: environmental pollutants; oxidative stress biomarkers; water/air/soil pollution; environmental toxicity; ROS and RNS
Phenolics as Antioxidant Agents—2nd Edition
edited by
submission deadline 10 Dec 2025 | Viewed by 121 | Submission Open
Keywords: antioxidants; bioactive compounds; oxidative stress; structure– activity relationships (SARs); sustainable extraction; green chemistry; therapeutic potential; in vitro and in vivo models; food and biomedical applications
(This special issue belongs to the Section Natural and Synthetic Antioxidants)
Redox Regulation in Algae
edited by
submission deadline 10 Dec 2025 | Viewed by 82 | Submission Open
Keywords: algae; reactive oxygen species; redox regulation; stress responses; NADPH oxidases; antioxidants; redox-sensitive transcription factors
(This special issue belongs to the Section ROS, RNS and RSS)
Applications of Antioxidant Nanoparticles, 2nd Edition submission deadline 15 Dec 2025 | 8 articles | Viewed by 18253 | Submission Open
(This special issue belongs to the Section Natural and Synthetic Antioxidants)
Harnessing Antioxidants: Pioneering Approaches in Cardiovascular Disease Prevention and Therapy
edited by and
submission deadline 15 Dec 2025 | 1 articles | Viewed by 2537 | Submission Open
Keywords: oxidative stress; reactive oxygen species (ROS); antioxidants; cardiovascular diseases
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Phytochemical Analysis and Evaluation of Antioxidant Properties in Medicinal Plants submission deadline 20 Dec 2025 | 7 articles | Viewed by 19552 | Submission Open
Keywords: antioxidant activity; phytochemicals in plants; medicinal plants; extraction; in vivo analysis; in vitro analysis
(This special issue belongs to the Section Natural and Synthetic Antioxidants)
Antioxidant and Anti-Inflammatory Properties of Mushrooms: From Structure to Functionality
edited by
submission deadline 20 Dec 2025 | 3 articles | Viewed by 10203 | Submission Open
Keywords: mushroom; antioxidants; metabolic syndrome; functional food; nutraceuticals; polysaccharides; phenolics; terpenoids
(This special issue belongs to the Section Natural and Synthetic Antioxidants)
Interplay of Microbiome and Oxidative Stress submission deadline 20 Dec 2025 | 3 articles | Viewed by 10030 | Submission Open
Keywords: microbiome; oxidative stress; antioxidants; gut microbiota; free radicals; reactive oxygen species; gut– brain axis; dysbiosis; microbial metabolites; mitochondrial function; probiotics; microbe– host interactions
The Use of Antioxidant-Rich Foods and Supplements in Disease Prevention submission deadline 20 Dec 2025 | 2 articles | Viewed by 8138 | Submission Open
Keywords: dietary antioxidants; bioactivity; metabolomics; human diet; xenobiotics; polyphenols; vitamins; health promotion
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Advances in Plant Redox Biology Research
edited by Yurong Xie and Ming Chang
submission deadline 20 Dec 2025 | Viewed by 207 | Submission Open
Keywords: plant redox biology; reactive oxygen species; reactive nitrogen species; plant development; environmental stress; abiotic/biotic stresses; host– microbe interactions
(This special issue belongs to the Section ROS, RNS and RSS)
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