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Antioxidants publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Synthetic Compounds: Antioxidant and Anti-Inflammatory Activities, Biomedical Properties and Formulations

edited by

Simone Carradori

and

Ilaria D'Agostino

submission deadline 20 Sep 2025 | 3 articles | Viewed by 5451 | Submission Open

Keywords: antioxidants; inflammation pathways; therapeutic activity; redox potential; synthesis; preclinical studies; macrophages; immunomodulation; packaging; formulations; topical application; polymers; nanotechnology; cytotoxicity; mechanism of action; food; drug design

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Mitochondrial Oxidative Stress and Inflammation

edited by Aldrin V. Gomes

submission deadline 20 Sep 2025 | 2 articles | Viewed by 4746 | Submission Open

Keywords: oxidative stress; mitochondria; antioxidants; disease; inflammation; mitochondrial oxidative stress

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Cigarette Smoke and Oxidative Stress

edited by

Lorenzo Loffredo

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1092 | Submission Open

Keywords: smoking; cardiovascular diseases; oxidative stress; cigarettes

Innovative Approaches to Antioxidant Activity and Polyphenol Extraction

edited by José Ricardo Pérez-Correa and

María Salomé Mariotti-Celis

submission deadline 20 Sep 2025 | Viewed by 444 | Submission Open

Keywords: polyphenols; novel antioxidant activity methods; sustainable separation technologies; innovative application techniques

(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)

Adaptive Responses to Oxidative Stress: Insights from Molecular, Cellular, and Animal Studies

edited by Ghasem Rashidian and

Caterina Faggio

submission deadline 24 Sep 2025 | 3 articles | Viewed by 3120 | Submission Open

Keywords: oxidative stress; antioxidant capacity; adaptive oxidative response; xenobiotics; pollutants; pesticides; natural antioxidants; antioxidant enzymes; reactive oxygen species (ROS); lipid peroxidation; redox homeostasis; oxidative damage; aquatic toxicology; stress response pathways; environmental stressors; cellular defense mechanisms; adaptive responses

Dietary Antioxidant Compounds and Liver Health: Pharmacological Activities and Molecular Mechanisms

edited by Juan Socorro Armendariz-Borunda, Marina Galicia-Moreno and Hugo Christian Monroy-Ramirez

submission deadline 25 Sep 2025 | 1 articles | Viewed by 1689 | Submission Open

Keywords: liver; oxidative stress; antioxidants; natural foods; MAFLD; NAFLD; obesity; liver function; hepatitis

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidants and Antioxidant Mechanisms in the Prevention and Treatment of Infectious Diseases

edited by

Gabriele Carullo

Maria Dichiara

Valeria Tudino

and Sara Rossi

submission deadline 25 Sep 2025 | 1 articles | Viewed by 868 | Submission Open

Keywords: antioxidants; infectious diseases; quorum sensing; inflammation; natural and synthetic antioxidants; oxidative stress

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Redox Signaling in Brain Aging and Neurodegeneration

edited by Marco Bisaglia

submission deadline 28 Sep 2025 | 2 articles | Viewed by 2183 | Submission Open

Keywords: aging; autophagy; brain; Alzheimer disease; amyotrophic lateral sclerosis; Friedreich ataxia; Huntington disease; neurodegeneration; oxidative stress; protein aggregation; Parkinson’ s disease; reactive oxygen species

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Bioactive Compounds: Antioxidant, Antibacterial, Anti-inflammatory Modulation

edited by

Raquel Bridi

and

Christian Espinosa-Bustos

submission deadline 30 Sep 2025 | 19 articles | Viewed by 93420 | Submission Open

Keywords: bioactive compounds; antioxidants; inflammation; antibacterial; reactive oxygen species

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Prevention of Atherosclerosis and of Low-Density Lipoprotein Oxidation: Role of Dietary Antioxidant Compounds and Altered Redox Pathways. A Commemorative Special Issue in Honour of Professor Stanley Omaye

edited by

Alessandra Napolitano

and

Mario Allegra

submission deadline 30 Sep 2025 | 5 articles | Viewed by 22629 | Submission Open

Keywords: LDL; oxidative stress; antioxidants; chronic; low-grade inflammation; vitamins; antioxidant enzymes; redox signalling

Role of Natural Antioxidants on Neuroprotection

edited by

Mercedes Villacampa

José Carlos Menéndez

and

Ángel Cores

submission deadline 30 Sep 2025 | 6 articles | Viewed by 18026 | Submission Open

Keywords: drug design; polyphenols; oxidative stress; Nrf2 induction; neuroinflammation; neurodegenerative diseases

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidants from Sustainable Food Sources

edited by

Kevin Kantono

and

Nazimah Hamid

submission deadline 30 Sep 2025 | 11 articles | Viewed by 16857 | Submission Open

Keywords: natural products; food processing; green technology

Use of Antioxidant Supplementation in Aquaculture: Impact on Growth, Health, and Product Quality

edited by

Luisa M. P. Valente

and Marta Monteiro

submission deadline 30 Sep 2025 | 5 articles | Viewed by 11104 | Submission Open

Keywords: functional feeds; oxidative stress; antioxidant supplementation; flesh quality; stress resilience

Antioxidant Capacity of Anthocyanins and Other Vegetal Pigments: Properties, Intake and Health Benefits

edited by

Agustín G. Asuero

Noelia Tena

and

Julia Martín

submission deadline 30 Sep 2025 | 7 articles | Viewed by 9114 | Submission Open

Keywords: anthocyanins; polyphenols; betalains; chlorophylls; carotenoids; antioxidant capacity; oxidative stress; bioavailability; intake

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Oxidative Stress in Chronic Diseases: A Focus on Rheumatoid Arthritis

edited by

Isaias Dichi

, Alexandre Meira Pazelli and

Bruna Miglioranza Scavuzzi

submission deadline 30 Sep 2025 | 2 articles | Viewed by 8951 | Submission Open

Keywords: rheumatic disorders; autoimmune conditions; oxidative stress; inflammation; redox state; antioxidant therapy

Oxidative Stress in Lung Diseases

edited by

Rudolf Lucas

submission deadline 30 Sep 2025 | 3 articles | Viewed by 8561 | Submission Open

Keywords: ROS; RNS; lung diseases; antioxidant defense; respiratory health

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Modern Analytical Approaches in the Identification of Polyphenols in Food, Food Sub-Products and Plant Matrices

edited by

Alina Plenis

submission deadline 30 Sep 2025 | 3 articles | Viewed by 6944 | Submission Open

Keywords: phenolic compounds; food; plants; extraction process; biological activity; analytical techniques; human health

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Bioactive Antioxidants from Agri-Food Wastes

edited by

Mia Kurek

and

Sabina Galus

submission deadline 30 Sep 2025 | 4 articles | Viewed by 6448 | Submission Open

Keywords: agri-food byproducts; waste; food industry; additives; packaging

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

NADPH Oxidases in Health and Aging—2nd Edition

edited by Marschall S. Runge and

Nageswara R. Madamanchi

submission deadline 30 Sep 2025 | 1 articles | Viewed by 6381 | Submission Open

Keywords: redox signaling; NADPH oxidases; reactive oxygen species (ROS); aging

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Exploring Plant-Derived Bioactive Compounds: The Role of Peptides, Polysaccharides, and Antioxidants in Nutriceutical Development and Health Promotion

edited by

Zhaohui Xue

submission deadline 30 Sep 2025 | 2 articles | Viewed by 4114 | Submission Open

Keywords: plant-derived bioactive peptides; polysaccharides; structure– activity relationship (SAR); molecular mechanisms; oxidative stress; hypolipidemic effects; antitumor capacity; apoptosis induction

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Oxidative/Nitrosative Stress in Cardiovascular Diseases

edited by

Claudia Penna

and Saveria Femminò

submission deadline 30 Sep 2025 | 2 articles | Viewed by 3784 | Submission Open

Keywords: oxidative stress; cardiovascular disease; therapeutic approaches; biomarkers; exercise; aging

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Polyphenol-Lipid Interactions in Nutrition and Health

edited by

Ana Reis

and

Maarit Karonen

submission deadline 30 Sep 2025 | 1 articles | Viewed by 2461 | Submission Open

Keywords: antibiotic resistance; animal feed; mouthfeel perception; bacterial growth; blood brain barrier; flavonoids; hydrolysable tannins; infection; (neuro)inflammation; microbial metabolites; nitric oxide; plant-based diets; phytochemicals; proanthocyanidins; vascular health

New Insight into Redox Homeostasis and Oxidative Stress in Health and Disease: Focus on Cardiac and Vascular Function

edited by

István Szokodi

and

Endre Sulyok

submission deadline 30 Sep 2025 | 2 articles | Viewed by 2275 | Submission Open

Keywords: reactive oxygen/nitrogen species; oxidative/nitrosative stress; redox signaling; atherosclerosis; hypertension; stroke; myocardial infarction; heart failure; biomarker; translational and precision medicine

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress and NRF2 in Diabetes

edited by

R. Paul Robertson

submission deadline 30 Sep 2025 | 1 articles | Viewed by 2093 | Submission Open

Keywords: oxidative stress; NRF2; ROS; diabetes; diabetes-related complications; insulin

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress in Age-Related Diseases

edited by

Gloria Olaso-Gonzalez

submission deadline 30 Sep 2025 | 1 articles | Viewed by 2034 | Submission Open

Keywords: aging; age-related diseases; frailty; oxidative stress; reductive stress; redox homeostasis; antioxidants

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress During Physical Activity

edited by

Ivan Dimauro

submission deadline 30 Sep 2025 | 1 articles | Viewed by 1651 | Submission Open

Keywords: physical activity; exercise; oxidative stress; reactive oxygen species (ROS); redox balance; cellular damage; skeletal muscle

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Reactive Oxygen Species Signalling and Oxidative Stress in Fish

edited by Daniela Vallone and

Nicholas S. Foulkes

submission deadline 30 Sep 2025 | 1 articles | Viewed by 1470 | Submission Open

Keywords: ROS; toxicology; fish; zebrafish; metabolism; immunity; cell signalling

Novel Antioxidant Mechanisms for Health and Diseases, 2nd Edition

edited by Yoshihisa Koyama

submission deadline 30 Sep 2025 | 1 articles | Viewed by 1469 | Submission Open

Keywords: antioxidant therapy; reactive oxygen species; oxidative stress; nano-antioxidant therapy; nutrigenomics; microbiome

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidant Activity of Grape and Grape By-Products

edited by

Cristiana Radulescu

and Radu Lucian Olteanu

submission deadline 30 Sep 2025 | Viewed by 279 | Submission Open

Keywords: antioxidants; grapes and grape by-products; extracts; cosmetic formulations; chromatography; microencapsulation; phytochemical profile; microbiological assay

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Plant Polyphenols in Human Health: Emerging Insights for Future Therapeutic Strategies

edited by

Vicente Micol

and

Francisco Javier Álvarez-Martínez

submission deadline 30 Sep 2025 | Viewed by 214 | Submission Open

Keywords: polyphenols; antioxidant properties; anti-inflammatory effects; metabolic stress; chronic disease prevention; gut microbiota; polyphenols metabolites; bioavailability; skin health; novel therapies

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidants and Their Application and Role in Bakery Products

edited by

Urszula Krupa-Kozak

and

Małgorzata Starowicz

submission deadline 30 Sep 2025 | Viewed by 194 | Submission Open

Keywords: antioxidants; antioxidant activity; phenolic compounds; vitamins; cereal-based conventional and gluten-free bakery products; plant-based by-products; fruits and vegetables; herbs; functional foods; health-related potential

(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)

Oxidative Stress and Skin Disorders: Therapeutic Potential of Antioxidants

edited by

Hideya Ando

submission deadline 30 Sep 2025 | Viewed by 181 | Submission Open

Keywords: ultraviolet radiation; reactive oxygen species; oxidative stress; skin disorders; skin aging

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Women’s Special Issue Series: Antioxidants in Human Health—2nd Edition

edited by

Simone Van Breda

and

Ruth Edge

submission deadline 30 Sep 2025 | Viewed by 177 | Submission Open

Keywords: oxidative stress; reactive oxygen species (ROS); antioxidants; vitamins; phytochemicals; molecular mechanisms; non-communicable diseases; human health; aging; clinical and public health applications

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidants and Oxidative Stress in Skin Health and Diseases

edited by

Yong Chool Boo

and

An Sang Mi

submission deadline 30 Sep 2025 | Viewed by 137 | Submission Open

Keywords: antioxidants; oxidative stress; skin health; skin disease; skin aging; cosmetics; dermatology; ultraviolet radiation; air pollution; glycation

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Bioactive Compounds in Functional Foods and Their Role in Combating Oxidative Stress

edited by

Luana Izzo

Alessandra Cimbalo

and Massimo Frangiamone

submission deadline 20 Oct 2025 | 2 articles | Viewed by 9424 | Submission Open

Keywords: bioactive compounds; functional foods; polyphenols; flavonoids; carotenoids; vitamins

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Redox Regulation in Inflammation and Disease—3rd Edition

edited by

Eva-Maria Hanschmann

, Mariana Ines Holubiec and

Christoph Hudemann

submission deadline 20 Oct 2025 | 2 articles | Viewed by 3329 | Submission Open

Keywords: redox signaling; reactive oxygen and nitrogen species; inflammation; signal transduction; thiol switches; regulation of immune cells; translational immunology

Antioxidant Peptides

edited by

Daniel Carneiro Moreira

and

José Roberto de Souza de Almeida Leite

submission deadline 30 Oct 2025 | 2 articles | Viewed by 1256 | Submission Open

Keywords: structure– activity relationships; novel natural or synthetic sources; advanced delivery systems; roles in preventing or alleviating oxidative stress-related diseases.

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Potential Health Benefits of Dietary Antioxidants

edited by

Irene Dini

submission deadline 31 Oct 2025 | 11 articles | Viewed by 43324 | Submission Open

Keywords: food antioxidants; food supplements; antioxidant activity; food antioxidant isolation; food antioxidant characterization; analytical method validation; antioxidant bioavailability; circular economy; sustainability

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Regulatory Effects of Curcumin, 2nd Edition

edited by

Jean-Marc Zingg

Kiyotaka Nakagawa

and

Taiki Miyazawa

submission deadline 31 Oct 2025 | 4 articles | Viewed by 26283 | Submission Open

Keywords: curcumin; antioxidant; prooxidant; bioavailability; bioactivity

Oxidative Stress and Liver Disease

edited by Alejandra Espinosa Escalona

submission deadline 31 Oct 2025 | 11 articles | Viewed by 19443 | Submission Open

Keywords: oxidative stress; antioxidants; MAFLD; NAFLD; obesity

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

The Role of Natural Antioxidants in Fruits and Vegetables in Human Health

edited by

Antonio Barberis

submission deadline 31 Oct 2025 | 2 articles | Viewed by 18219 | Submission Open

Keywords: antioxidants; anti-inflammation; oxidative stress; fruits; vegetables; oxidation reactions; functional foods

Oxidative Stress as a Therapeutic Target of Alzheimer’s Disease

edited by

Marcello Leopoldo

and

Leonardo Brunetti

submission deadline 31 Oct 2025 | 7 articles | Viewed by 17416 | Submission Open

Keywords: Alzheimer's disease; neuroinflammation; therapeutic agent; oxidative stress

Antioxidant Role of High-Density Lipoprotein

edited by Paul Durrington

submission deadline 31 Oct 2025 | 8 articles | Viewed by 17154 | Submission Open

Keywords: lipoprotein oxidation; cell membrane oxidation; HDL antioxidant activity; glycosylation; atherosclerosis

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress Induced by Air Pollution, 2nd Edition

edited by

Yasuhiro Yoshida

submission deadline 31 Oct 2025 | 6 articles | Viewed by 11598 | Submission Open

Keywords: particulate matter; air pollution; oxidative stress; reactive oxygen species; inflammation

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Anti-Cancer Potential of Plant-Based Antioxidants

edited by

Javier Espino

María Garrido

and

Jonathan Delgado-Adamez

submission deadline 31 Oct 2025 | 6 articles | Viewed by 9438 | Submission Open

Keywords: cancer; antitumor activity; medicinal plants; natural antioxidants; polyphenols; terpenoids; carotenoids

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Reactive Oxygen Species and Growth Factors in Photodynamic Therapy (PDT), Photobiomodulation (PBM), and Radiation Therapy (RT)

edited by Timothy C. Zhu and Brian C. Wilson

submission deadline 31 Oct 2025 | 5 articles | Viewed by 8451 | Submission Open

Keywords: reactive oxygen species (ROS); singlet oxygen (SO); radiation; photodynamic therapy; cancers

(This special issue belongs to the Section ROS, RNS and RSS)

Implication of Oxidative Stress in Promoting Cellular Senescence and Associated Pathologies—2nd Edition

edited by

Alexandra Barbouti

submission deadline 31 Oct 2025 | 6 articles | Viewed by 8234 | Submission Open

Keywords: oxidative stress; free radicals; reactive oxygen species (ROS); cellular senescence; ageing; age-related pathologies

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Green Extraction of Antioxidant from Natural Source

edited by

Jolanta Flieger

submission deadline 31 Oct 2025 | 5 articles | Viewed by 7256 | Submission Open

Keywords: green extraction techniques ; supercritical fluid extraction ; ionic liquid (IL)-based extraction; microwave-assisted extraction; antioxidants; plants; cosmetic formulation

Oxidative Stress and Inflammation in Bone Metabolism and Diseases

edited by

Jin Kyeong Choi

submission deadline 31 Oct 2025 | 4 articles | Viewed by 7172 | Submission Open

Keywords: oxidative stress; immune system; inflammation; joint inflammation; bone; metabolism pathways

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Valorization of Waste Through Antioxidant Extraction and Utilization

edited by

Andrés Moreno

submission deadline 31 Oct 2025 | 4 articles | Viewed by 5732 | Submission Open

Keywords: valorization; waste management; green extraction; antioxidants; value-added products; by-products

(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)

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