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J. Fungi 2015, 1(2), 277-292; doi:10.3390/jof1020277

Candida glabrata, Friend and Foe

School of Applied Sciences, RMIT University, Bundoora, Victoria 3083, Australia
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Author to whom correspondence should be addressed.
Academic Editor: John R. Perfect
Received: 18 August 2015 / Revised: 7 September 2015 / Accepted: 9 September 2015 / Published: 16 September 2015
(This article belongs to the Special Issue Yeasts Are Beasts)
View Full-Text   |   Download PDF [911 KB, uploaded 16 September 2015]   |  

Abstract

Candida glabrata is mostly good, but, at times, it is an opportunistic pathogen. Previously known as Torulopsis glabrata, it enjoyed a good reputation and was even present in starter cultures. Its haploid genome and lack of mating made it an attractive challenge for yeast genetics studies. However, more recently it has become better known due to its character as an emerging cause of candidiasis, and for its resistance to multidrugs that are employed for candidiasis treatment. While now classified as Candida glabrata, it is still not a good fit and tends to stand alone as a very unique yeast. In terms of sequence, it is dissimilar to other Candida yeast and most similar to Saccharomyces cerevisiae. View Full-Text
Keywords: antifungal resistance; azole; candidiasis; ergosterol; opportunistic pathogen; starter culture; statins; Torulopsis; yeast antifungal resistance; azole; candidiasis; ergosterol; opportunistic pathogen; starter culture; statins; Torulopsis; yeast
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Tam, P.; Gee, K.; Piechocinski, M.; Macreadie, I. Candida glabrata, Friend and Foe. J. Fungi 2015, 1, 277-292.

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