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J. Fungi 2015, 1(2), 217-251; doi:10.3390/jof1020217

Application of Culture-Independent Rapid Diagnostic Tests in the Management of Invasive Candidiasis and Cryptococcosis

1
University of Iowa College of Medicine, Iowa City, IA 52242, USA
2
University of Iowa College of Public Health, Iowa City, IA 52242, USA
3
Biosystems, Lexington, MA 02421, USA 
Academic Editor: John R. Perfect
Received: 22 July 2015 / Revised: 17 August 2015 / Accepted: 17 August 2015 / Published: 31 August 2015
(This article belongs to the Special Issue Yeasts Are Beasts)
View Full-Text   |   Download PDF [748 KB, uploaded 31 August 2015]

Abstract

The diagnosis of invasive candidiasis (IC) and cryptococcosis is often complicated by slow and insensitive culture-based methods. Such delay results in poor outcomes due to the lack of timely therapeutic interventions. Advances in serological, biochemical, molecular and proteomic approaches have made a favorable impact on this process, improving the timeliness and accuracy of diagnosis with resultant improvements in outcome. This paper will serve as an overview of recent developments in the diagnostic approaches to infections due to these important yeast-fungi. View Full-Text
Keywords: candidasis; cryptococcosis; rapid diagnosis; invasive fungal infection candidasis; cryptococcosis; rapid diagnosis; invasive fungal infection
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Pfaller, M.A. Application of Culture-Independent Rapid Diagnostic Tests in the Management of Invasive Candidiasis and Cryptococcosis. J. Fungi 2015, 1, 217-251.

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