Next Article in Journal
New Biological Activities of Lythrum salicaria L.: Effects on Keratinocytes, Reconstructed Epidermis and Reconstructed Skins, Applications in Dermo-Cosmetic Sciences
Previous Article in Journal
Castanea sativa Bur: An Undervalued By-Product but a Promising Cosmetic Ingredient
Article Menu

Export Article

Open AccessArticle
Cosmetics 2017, 4(4), 51; doi:10.3390/cosmetics4040051

Whitening Agents from Reseda luteola L. and Their Chemical Characterization Using Combination of CPC, UPLC-HRMS and NMR

1
Université Côte d’Azur, CNRS, Institut de Chimie de Nice UMR7272, 06108 Nice, France
2
Université Européenne des Senteurs et des Saveurs, Pôle de Compétitivité Parfums, Arômes, Senteurs, Saveurs, Couvent des Cordeliers, 04300 Forcalquier, France
3
Parc naturel régional du Luberon, 60 place Jean Jaurès, 84400 Apt, France
*
Author to whom correspondence should be addressed.
Received: 5 November 2017 / Revised: 22 November 2017 / Accepted: 23 November 2017 / Published: 25 November 2017
(This article belongs to the Special Issue Plants Used in Cosmetics)
View Full-Text   |   Download PDF [1155 KB, uploaded 25 November 2017]   |  

Abstract

Skin whitening agents occupy an important part of the dermo-cosmetic market nowadays. They are used to treat various skin pigmentation disorders, or simply to obtain a lighter skin tone. The use of traditional skin bleachers (e.g., hydroquinone, corticoids) is now strictly regulated due to their side effects. When considering this and the growing consumers’ interest for more natural ingredients, plant extracts can be seen as safe and natural alternatives. In this perspective, in vitro bioassays were undertaken to assess cosmetic potential of Reseda luteola, and particularly its promising whitening activities. A bioguided purification procedure employing centrifugal partition chromatography, Ultra Performance Liquid Chromatography-Mass Spectrometry (UPLC-HRMS) and NMR was developed to isolate and identify the whitening agents (i.e., luteolin and apigenin) from aerial parts of R. luteola. UPLC-HRMS also enabled the characterization of acetylated luteolin- and apigenin-O-glycosides, which occurrence is reported for the first time in R. luteola. View Full-Text
Keywords: Reseda luteola; UPLC-HRMS; biological activity; centrifugal partition chromatography; luteolin; apigenin Reseda luteola; UPLC-HRMS; biological activity; centrifugal partition chromatography; luteolin; apigenin
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Supplementary material

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Burger, P.; Monchot, A.; Bagarri, O.; Chiffolleau, P.; Azoulay, S.; Fernandez, X.; Michel, T. Whitening Agents from Reseda luteola L. and Their Chemical Characterization Using Combination of CPC, UPLC-HRMS and NMR. Cosmetics 2017, 4, 51.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Cosmetics EISSN 2079-9284 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top