Cosmetics 2014, 1(3), 202-210; doi:10.3390/cosmetics1030202
Article

Liquid Crystal Gel Reduces Age Spots by Promoting Skin Turnover

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Received: 7 March 2014; in revised form: 4 July 2014 / Accepted: 18 July 2014 / Published: 25 July 2014
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Abstract: Studies have shown that liquid crystals structurally resembling the intercellular lipids in the stratum corneum can beneficially affect the skin when applied topically by stimulating the skin’s natural regenerative functions and accelerating epidermal turnover. In the present study, the effects of applying low concentrations of a liquid crystal gel of our own creation were evaluated using epidermal thickening in mouse skin as an assay for effective stimulation of epidermal turnover. A liquid crystal gel was also applied topically to human facial skin, and analysis was conducted using before-and-after photographs of age spots, measurements of L* values that reflect degree of skin pigmentation, single-layer samples of the stratum corneum obtained via tape-stripping, and measurements of trans-epidermal water loss that reflect the status of the skin’s barrier function. The results suggested that cost-effective creams containing as low as 5% liquid crystal gel might be effective and safely sold as skin care products targeting age spots and other problems relating to uneven skin pigmentation.
Keywords: liquid crystal; skin turnover; intercellular lipids; stratum corneum; age spots; skin care
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Musashi, M.; Coler-Reilly, A.; Nagasawa, T.; Kubota, Y.; Kato, S.; Yamaguchi, Y. Liquid Crystal Gel Reduces Age Spots by Promoting Skin Turnover. Cosmetics 2014, 1, 202-210.

AMA Style

Musashi M, Coler-Reilly A, Nagasawa T, Kubota Y, Kato S, Yamaguchi Y. Liquid Crystal Gel Reduces Age Spots by Promoting Skin Turnover. Cosmetics. 2014; 1(3):202-210.

Chicago/Turabian Style

Musashi, Mina; Coler-Reilly, Ariella; Nagasawa, Teruaki; Kubota, Yoshiki; Kato, Satomi; Yamaguchi, Yoko. 2014. "Liquid Crystal Gel Reduces Age Spots by Promoting Skin Turnover." Cosmetics 1, no. 3: 202-210.

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