Antibiotics 2014, 3(2), 174-192; doi:10.3390/antibiotics3020174
Review

Antimicrobial Stewardship and Urinary Tract Infections

* email and email
Received: 14 March 2014; in revised form: 10 April 2014 / Accepted: 21 April 2014 / Published: 5 May 2014
(This article belongs to the Special Issue Antibiotics and Urinary Tract Infections)
View Full-Text   |   Download PDF [597 KB, uploaded 5 May 2014]
Abstract: Urinary tract infections are the most common bacterial infections encountered in ambulatory and long-term care settings in the United States. Urine samples are the largest single category of specimens received by most microbiology laboratories and many such cultures are collected from patients who have no or questionable urinary symptoms. Unfortunately, antimicrobials are often prescribed inappropriately in such patients. Antimicrobial use, whether appropriate or inappropriate, is associated with the selection for antimicrobial-resistant organisms colonizing or infecting the urinary tract. Infections caused by antimicrobial-resistant organisms are associated with higher rates of treatment failures, prolonged hospitalizations, increased costs and mortality. Antimicrobial stewardship consists of avoidance of antimicrobials when appropriate and, when antimicrobials are indicated, use of strategies to optimize the selection, dosing, route of administration, duration and timing of antimicrobial therapy to maximize clinical cure while limiting the unintended consequences of antimicrobial use, including toxicity and selection of resistant microorganisms. This article reviews successful antimicrobial stewardship strategies in the diagnosis and treatment of urinary tract infections.
Keywords: antimicrobial stewardship; antimicrobial resistance; UTI; urinary tract infections; antibiotics; duration; appropriate
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Export to BibTeX |
EndNote


MDPI and ACS Style

Abbo, L.M.; Hooton, T.M. Antimicrobial Stewardship and Urinary Tract Infections. Antibiotics 2014, 3, 174-192.

AMA Style

Abbo LM, Hooton TM. Antimicrobial Stewardship and Urinary Tract Infections. Antibiotics. 2014; 3(2):174-192.

Chicago/Turabian Style

Abbo, Lilian M.; Hooton, Thomas M. 2014. "Antimicrobial Stewardship and Urinary Tract Infections." Antibiotics 3, no. 2: 174-192.

Antibiotics EISSN 2079-6382 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert