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Nanomaterials 2017, 7(3), 63;

Nanofibrous Silver-Coated Polymeric Scaffolds with Tunable Electrical Properties

Center of Nanotechnology, King Abdulaziz University, Jeddah 21569, Saudi Arabia
Department of Biochemistry, King Abdulaziz University, Jeddah 21569, Saudi Arabia
Biomaterials Innovation Research Center (BIRC), Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02139, USA
Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115, USA
Department of Chemical Engineering, Northeastern University, Boston, MA 02115-5000, USA
Sorbonne University, UTC CNRS UMR 7338, Biomechanics and Bioengineering (BMBI), University of Technology of Compiègne, BP 20529, Rue Personne de Roberval, 60205 Compiègne, France
School of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138, USA
Department of Bioindustrial Technologies, College of Animal Bioscience and Technology, Konkuk University, Seoul 05029, Korea
Author to whom correspondence should be addressed.
Academic Editor: Thomas Nann
Received: 2 January 2017 / Revised: 4 March 2017 / Accepted: 9 March 2017 / Published: 13 March 2017
(This article belongs to the Special Issue Nanofibrous Scaffolds for Biomedical Application)
View Full-Text   |   Download PDF [2160 KB, uploaded 13 March 2017]   |  


Electrospun micro- and nanofibrous poly(glycerol sebacate)-poly(ε-caprolactone) (PGS-PCL) substrates have been extensively used as scaffolds for engineered tissues due to their desirable mechanical properties and their tunable degradability. In this study, we fabricated micro/nanofibrous scaffolds from a PGS-PCL composite using a standard electrospinning approach and then coated them with silver (Ag) using a custom radio frequency (RF) sputtering method. The Ag coating formed an electrically conductive layer around the fibers and decreased the pore size. The thickness of the Ag coating could be controlled, thereby tailoring the conductivity of the substrate. The flexible, stretchable patches formed excellent conformal contact with surrounding tissues and possessed excellent pattern-substrate fidelity. In vitro studies confirmed the platform’s biocompatibility and biodegradability. Finally, the potential controlled release of the Ag coating from the composite fibrous scaffolds could be beneficial for many clinical applications. View Full-Text
Keywords: electrospinning; electrical properties; nanocoatings; flexible electronics electrospinning; electrical properties; nanocoatings; flexible electronics

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Memic, A.; Aldhahri, M.; Tamayol, A.; Mostafalu, P.; Abdel-wahab, M.S.; Samandari, M.; Moghaddam, K.M.; Annabi, N.; Bencherif, S.A.; Khademhosseini, A. Nanofibrous Silver-Coated Polymeric Scaffolds with Tunable Electrical Properties. Nanomaterials 2017, 7, 63.

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