Stimuli-Responsive Gold Nanoparticles for Cancer Diagnosis and Therapy
AbstractAn emerging concept is that cancers strongly depend on both internal and external signals for growth and invasion. In this review, we will discuss pathological and physical changes in the tumor microenvironment and how these changes can be exploited to design gold nanoparticles for cancer diagnosis and therapy. These intrinsic changes include extracellular and intracellular pH, extracellular matrix enzymes, and glutathione concentration. External stimuli include the application of laser, ultrasound and X-ray. The biology behind these changes and the chemistry behind the responding mechanisms to these changes are reviewed. Examples of recent in vitro and in vivo studies are also presented, and the clinical implications of these findings are discussed. View Full-Text
Scifeed alert for new publicationsNever miss any articles matching your research from any publisher
- Get alerts for new papers matching your research
- Find out the new papers from selected authors
- Updated daily for 49'000+ journals and 6000+ publishers
- Define your Scifeed now
Tian, L.; Lu, L.; Qiao, Y.; Ravi, S.; Salatan, F.; Melancon, M.P. Stimuli-Responsive Gold Nanoparticles for Cancer Diagnosis and Therapy. J. Funct. Biomater. 2016, 7, 19.
Tian L, Lu L, Qiao Y, Ravi S, Salatan F, Melancon MP. Stimuli-Responsive Gold Nanoparticles for Cancer Diagnosis and Therapy. Journal of Functional Biomaterials. 2016; 7(3):19.Chicago/Turabian Style
Tian, Li; Lu, Linfeng; Qiao, Yang; Ravi, Saisree; Salatan, Ferandre; Melancon, Marites P. 2016. "Stimuli-Responsive Gold Nanoparticles for Cancer Diagnosis and Therapy." J. Funct. Biomater. 7, no. 3: 19.
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.