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J. Funct. Biomater. 2016, 7(3), 18; doi:10.3390/jfb7030018

Effect of Nanoparticle Incorporation and Surface Coating on Mechanical Properties of Bone Scaffolds: A Brief Review

1
Department of Mechanical Engineering, University of Saskatchewan, 57 Campus Drive, Saskatoon, SK S7H 5A9, Canada
2
Division of Biomedical Engineering, University of Saskatchewan, 57 Campus Drive, Saskatoon, SK S7H 5A9, Canada
*
Author to whom correspondence should be addressed.
Academic Editor: Francesco Puoci
Received: 26 April 2016 / Revised: 27 June 2016 / Accepted: 1 July 2016 / Published: 12 July 2016
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Abstract

Mechanical properties of a scaffold play an important role in its in vivo performance in bone tissue engineering, due to the fact that implanted scaffolds are typically subjected to stress including compression, tension, torsion, and shearing. Unfortunately, not all the materials used to fabricate scaffolds are strong enough to mimic native bones. Extensive research has been conducted in order to increase scaffold strength and mechanical performance by incorporating nanoparticles and/or coatings. An incredible improvement has been achieved; and some outstanding examples are the usage of nanodiamond, hydroxyapatite, bioactive glass particles, SiO2, MgO, and silver nanoparticles. This review paper aims to present the results, to summarize significant findings, and to give perspective for future work, which could be beneficial to future bone tissue engineering. View Full-Text
Keywords: tissue engineering; mechanical properties; scaffold design; scaffold fabrication; biomaterials; nanodiamond; hydroxyapatite; bioactive glass particles; silver nanoparticles; surface coating tissue engineering; mechanical properties; scaffold design; scaffold fabrication; biomaterials; nanodiamond; hydroxyapatite; bioactive glass particles; silver nanoparticles; surface coating
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Corona-Gomez, J.; Chen, X.; Yang, Q. Effect of Nanoparticle Incorporation and Surface Coating on Mechanical Properties of Bone Scaffolds: A Brief Review. J. Funct. Biomater. 2016, 7, 18.

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