J. Funct. Biomater. 2012, 3(1), 163-172; doi:10.3390/jfb3010163
Communication

Development of Ti-Coated Ferromagnetic Needle, Adaptable for Ablation Cancer Therapy by High-Frequency Induction Heating

Received: 28 November 2011; in revised form: 1 March 2012 / Accepted: 2 March 2012 / Published: 6 March 2012
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: To develop a novel ablation therapy for human solid cancer, the heating properties of a ferromagnetic carbon steel rod and a prototype Ti-coated needle using this carbon steel rod, were investigated in several high-frequency outputs at 300 kHz. In the former, the heating property was drastically different among the three inclination angles (θ = 0°, 45° and 90°) relative to the magnetic flux direction as a result of the shape magnetic anisotropy. However, the effect of the inclination angles was completely eliminated in the latter. It is considered that the complete non-oriented heating property relative to the magnetic flux direction allows the precise control of the ablation temperature during minimally invasive thermotherapy without a lead-wire connected to a fiber-optic thermometer. This newly designed Ti-coated device will be suitable for clinical use combined with its superior biocompatibility for ablation treatments using high-frequency induction heating.
Keywords: cancer therapy; ablation treatment; high-frequency induction heating; AC magnetic field; shape magnetic anisotropy; magnetic flux direction; biocompatibility
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MDPI and ACS Style

Naohara, T.; Aono, H.; Maehara, T.; Hirazawa, H.; Matsutomo, S.; Watanabe, Y. Development of Ti-Coated Ferromagnetic Needle, Adaptable for Ablation Cancer Therapy by High-Frequency Induction Heating. J. Funct. Biomater. 2012, 3, 163-172.

AMA Style

Naohara T, Aono H, Maehara T, Hirazawa H, Matsutomo S, Watanabe Y. Development of Ti-Coated Ferromagnetic Needle, Adaptable for Ablation Cancer Therapy by High-Frequency Induction Heating. Journal of Functional Biomaterials. 2012; 3(1):163-172.

Chicago/Turabian Style

Naohara, Takashi; Aono, Hiromichi; Maehara, Tsunehiro; Hirazawa, Hideyuki; Matsutomo, Shinya; Watanabe, Yuji. 2012. "Development of Ti-Coated Ferromagnetic Needle, Adaptable for Ablation Cancer Therapy by High-Frequency Induction Heating." J. Funct. Biomater. 3, no. 1: 163-172.

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