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Appl. Sci. 2012, 2(2), 443-452; doi:10.3390/app2020443

Further Successes of the Meisenheimer Model

*  and
Parallel Quantum Solutions, 2013 Green Acres Road, Suite A, Fayetteville, AR 72703, USA
* Author to whom correspondence should be addressed.
Received: 5 April 2012 / Revised: 27 April 2012 / Accepted: 27 April 2012 / Published: 4 May 2012
(This article belongs to the Special Issue Organo-Fluorine Chemical Science)
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Our simple Meisenheimer model for predicting the principal site for nucleophilic substitution in aromatic perfluorocarbons is further tested on a series of recently published reactions in liquid ammonia primarily from Malykhin and coworkers. The model accurately predicts the experimental results for all of the reactions reported further confirming its general applicability.
Keywords: nucleophilic substitution; fluorine-containing hetero-aromatics; Meisenheimer model nucleophilic substitution; fluorine-containing hetero-aromatics; Meisenheimer model
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Baker, J.B.; Muir, M. Further Successes of the Meisenheimer Model. Appl. Sci. 2012, 2, 443-452.

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