Appl. Sci. 2012, 2(2), 368-374; doi:10.3390/app2020368
Article

Synthesis of Some New Fluorinated Hexahydroquinoline and Acridinedione Derivatives in Trifluoroethanol

* email, email and email
Received: 29 January 2012; in revised form: 6 April 2012 / Accepted: 9 April 2012 / Published: 18 April 2012
(This article belongs to the Special Issue Organo-Fluorine Chemical Science)
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: This article describes one-pot synthesis of new fluorinated hexahydroquinoline derivatives via unsymmetric Hantzsch reaction involving 5-trifluoromethyl-1,3-cyclohexanedione, aldehydes, acetoacetate ester, and ammonium acetate in trifluoroethanol (TFE). The reaction is simple and rapid with high yield.
Keywords: unsymmetric Hantzsch reaction; dihydropyridine; trifluoromethyl; hexahydroquinoline; acridinedione; trifluoroethanol
PDF Full-text Download PDF Full-Text [248 KB, Updated Version, uploaded 20 April 2012 11:23 CEST]
The original version is still available [248 KB, uploaded 18 April 2012 11:38 CEST]

Export to BibTeX |
EndNote


MDPI and ACS Style

Okoro, C.O.; Ogunwale, M.A.; Siddiquee, T. Synthesis of Some New Fluorinated Hexahydroquinoline and Acridinedione Derivatives in Trifluoroethanol. Appl. Sci. 2012, 2, 368-374.

AMA Style

Okoro CO, Ogunwale MA, Siddiquee T. Synthesis of Some New Fluorinated Hexahydroquinoline and Acridinedione Derivatives in Trifluoroethanol. Applied Sciences. 2012; 2(2):368-374.

Chicago/Turabian Style

Okoro, Cosmas O.; Ogunwale, Mumiye A.; Siddiquee, Tasneem. 2012. "Synthesis of Some New Fluorinated Hexahydroquinoline and Acridinedione Derivatives in Trifluoroethanol." Appl. Sci. 2, no. 2: 368-374.

Appl. Sci. EISSN 2076-3417 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert