Appl. Sci. 2012, 2(2), 245-259; doi:10.3390/app2020245
Review

Nucleic Acid Based Fluorinated Derivatives: New Tools for Biomedical Applications

Christel Dolain 1 email, Amit Patwa 1,2 email, Guilhem Godeau 1,2 email and Philippe Barthélémy 1,2,* email
1 Université de Bordeaux, Bordeaux F-33076, France 2 INSERM U869, Bordeaux F-33076, France
* Author to whom correspondence should be addressed.
Received: 14 January 2012; in revised form: 13 March 2012 / Accepted: 14 March 2012 / Published: 23 March 2012
(This article belongs to the Special Issue Organo-Fluorine Chemical Science)
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Abstract: Nucleic acid-based fluorinated derivatives, e.g., nucleosides or oligonucleotides connected to highly fluorinated chains or labeled with one or more fluorine atoms, have been investigated recently due to their high potential for biomedical applications. This review deals with recent works on nucleoside and oligonucleotide fluorocarbon amphiphiles as well as with properties and applications of fluorine-labeled oligonucleotide analogues.
Keywords: fluorocarbon; amphiphile; lipids; nucleoside; oligonucleotides

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Cite This Article

MDPI and ACS Style

Dolain, C.; Patwa, A.; Godeau, G.; Barthélémy, P. Nucleic Acid Based Fluorinated Derivatives: New Tools for Biomedical Applications. Appl. Sci. 2012, 2, 245-259.

AMA Style

Dolain C, Patwa A, Godeau G, Barthélémy P. Nucleic Acid Based Fluorinated Derivatives: New Tools for Biomedical Applications. Applied Sciences. 2012; 2(2):245-259.

Chicago/Turabian Style

Dolain, Christel; Patwa, Amit; Godeau, Guilhem; Barthélémy, Philippe. 2012. "Nucleic Acid Based Fluorinated Derivatives: New Tools for Biomedical Applications." Appl. Sci. 2, no. 2: 245-259.

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