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Appl. Sci. 2012, 2(2), 245-259; doi:10.3390/app2020245

Nucleic Acid Based Fluorinated Derivatives: New Tools for Biomedical Applications

Université de Bordeaux, Bordeaux F-33076, France
INSERM U869, Bordeaux F-33076, France
Author to whom correspondence should be addressed.
Received: 14 January 2012 / Revised: 13 March 2012 / Accepted: 14 March 2012 / Published: 23 March 2012
(This article belongs to the Special Issue Organo-Fluorine Chemical Science)
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Nucleic acid-based fluorinated derivatives, e.g., nucleosides or oligonucleotides connected to highly fluorinated chains or labeled with one or more fluorine atoms, have been investigated recently due to their high potential for biomedical applications. This review deals with recent works on nucleoside and oligonucleotide fluorocarbon amphiphiles as well as with properties and applications of fluorine-labeled oligonucleotide analogues.
Keywords: fluorocarbon; amphiphile; lipids; nucleoside; oligonucleotides fluorocarbon; amphiphile; lipids; nucleoside; oligonucleotides

This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Dolain, C.; Patwa, A.; Godeau, G.; Barthélémy, P. Nucleic Acid Based Fluorinated Derivatives: New Tools for Biomedical Applications. Appl. Sci. 2012, 2, 245-259.

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