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CCL21 Cancer Immunotherapy
AbstractCancer, a major health problem, affects 12 million people worldwide every year. With surgery and chemo-radiation the long term survival rate for the majority of cancer patients is dismal. Thus novel treatments are urgently needed. Immunotherapy, the harnessing of the immune system to destroy cancer cells is an attractive option with potential for long term anti-tumor benefit. Cytokines are biological response modifiers that stimulate anti-tumor immune responses. In this review, we discuss the anti-tumor efficacy of the chemotactic cytokine CCL21 and its pre-clinical and clinical application in cancer.
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Lin, Y.; Sharma, S.; John, M.S. CCL21 Cancer Immunotherapy. Cancers 2014, 6, 1098-1110.View more citation formats
Lin Y, Sharma S, John MS. CCL21 Cancer Immunotherapy. Cancers. 2014; 6(2):1098-1110.Chicago/Turabian Style
Lin, Yuan; Sharma, Sherven; John, Maie S. 2014. "CCL21 Cancer Immunotherapy." Cancers 6, no. 2: 1098-1110.