Special Issue "Cytokines in Cancer"


A special issue of Cancers (ISSN 2072-6694).

Deadline for manuscript submissions: closed (20 January 2014)

Special Issue Editor

Guest Editor
Dr. Howard A. Young
Principal Investigator & Deputy Lab Chief, Laboratory of Experimental Immunology, Cancer and Inflammation Program, Center for Cancer Research, Frederick National Laboratory for Cancer Research, Bldg. 560/31-23, Chandler Street, Frederick, MD 21702-1201, USA
E-Mail: younghow@mail.nih.gov
Phone: +1 301 846 5700
Fax: +1 301 846 1673
Interests: interferon-gamma; post transcriptional regulation; NK cells; interleukins

Special Issue Information

Dear Colleagues,

Cancer is a complex disease that is regulated during its initiation, development, and progression by many different host factors. Cytokines play an important role in all aspects of cancer biology. Cytokines trigger specific signal transduction pathways within cancer cells and, in the tumor microenvironment, greatly impact the tumor cell itself as well as the host response to the malignancy. Furthermore, cytokines and interferons now play an important role in cancer immunotherapies, as they are being used to direct immune effector cells to directly attack and destroy the tumor cells. In this issue, "Cytokines and Cancer," authors are invited to contribute original research papers or review articles that will provide further insights on the direct impact of cytokines on cancer cells, the biological significance of cytokine production by tumor cells, the role of cytokines on the tumor microenvironment, and the use of cytokines to manipulate the host response as a treatment for the disease.

Dr. Howard A. Young (EBM of Pharmaceuticals)
Guest Editor


Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed Open Access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 800 CHF (Swiss Francs).


  • cytokines
  • interleukins
  • interferon
  • cancer
  • innate immunity
  • immunotherapy

Published Papers (3 papers)

Cancers 2014, 6(2), 756-770; doi:10.3390/cancers6020756
Received: 10 January 2014; in revised form: 12 March 2014 / Accepted: 14 March 2014 / Published: 2 April 2014
Show/Hide Abstract | Download PDF Full-text (574 KB) | Download XML Full-text

Cancers 2014, 6(2), 741-755; doi:10.3390/cancers6020741
Received: 8 February 2014; in revised form: 8 March 2014 / Accepted: 11 March 2014 / Published: 26 March 2014
Show/Hide Abstract | Download PDF Full-text (978 KB) | Download XML Full-text

Cancers 2014, 6(2), 663-683; doi:10.3390/cancers6020663
Received: 26 February 2014; in revised form: 11 March 2014 / Accepted: 12 March 2014 / Published: 25 March 2014
Show/Hide Abstract | Download PDF Full-text (5474 KB) | Download XML Full-text

Last update: 22 August 2013

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