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Surgery of Primary Melanomas
Cancers 2010, 2(2), 955-969; doi:10.3390/cancers2020955

Systemic Therapy of Non-Resectable Metastatic Melanoma

Department of Dermatology, Venereology and Allergology, University Medical Center Mannheim, Ruprecht-Karl University of Heidelberg, Mannheim, Germany
* Author to whom correspondence should be addressed.
Received: 8 March 2010 / Revised: 11 May 2010 / Accepted: 12 May 2010 / Published: 26 May 2010
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In advanced metastatic melanoma (non-resectable stage III/IV), the prognosis still remains poor, with median survival times between six and twelve months. Systemic therapeutic approaches for metastatic melanoma include chemotherapy, immunotherapy, immunochemotherapy, small molecules and targeted therapy. In this review, we will focus on the various treatment modalities as well as new agents used for targeted therapy.
Keywords: melanoma; metastatic; chemotherapy; targeted therapy; small molecules melanoma; metastatic; chemotherapy; targeted therapy; small molecules
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Orouji, A.; Goerdt, S.; Utikal, J. Systemic Therapy of Non-Resectable Metastatic Melanoma. Cancers 2010, 2, 955-969.

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