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Cancers 2010, 2(2), 498-512; doi:10.3390/cancers2020498
Review

Possible DNA Viral Factors of Human Breast Cancer

1,
,
2,3,
,
2
 and
2,4,5,*
1 Department of Microbiology, National Taiwan University College of Medicine, 1, Jen Ai Road, Sec. 1, Taipei 100, Taiwan 2 Institute of Medicine, Chung Shan Medical University, Taichung, 110, Section 1, Chien-Kuo North Road, Taichung 40201, Taiwan 3 Department of Neurology, Chung Shan Medical University Hospital, 110, Section 1, Chien-Kuo North Road, Taichung 40201, Taiwan 4 School of Medical Laboratory and Biotechnology, Chung Shan Medical University, 110, Section 1, Chien-Kuo North Road, Taichung 40201, Taiwan 5 Department of Clinical Laboratory, Chung Shan Medical University Hospital, 110, Section 1, Chien-Kuo North Road, Taichung 40201, Taiwan Dr. Chun-Ru Hsu and Dr. Tsong-Ming Lu contributed equally.
* Author to whom correspondence should be addressed.
Received: 1 March 2010 / Revised: 3 April 2010 / Accepted: 12 April 2010 / Published: 13 April 2010
(This article belongs to the Special Issue Breast Cancer)
View Full-Text   |   Download PDF [1006 KB, uploaded 13 April 2010]

Abstract

Viruses are considered to be one of the high-risk factors closely related to human breast cancer. However, different studies of viruses in breast cancer present conflicting results and some of these works remain in dispute. DNA viruses, such as specific types of human papillomaviruses (HPV), Epstein–Barr virus (EBV), human cytomegalovirus (HCMV), herpes simplex virus (HSV), and human herpes virus type 8 (HHV-8), have emerged as causal factors of some human cancers. These respective exogenous viruses and the possibility of multiple viral factors are discussed in this review.
Keywords: Epstein–Barr virus; cytomegalovirus; herpes simplex virus; human herpes virus type 8; papillomaviruses Epstein–Barr virus; cytomegalovirus; herpes simplex virus; human herpes virus type 8; papillomaviruses
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Hsu, C.-R.; Lu, T.-M.; Chin, L.W.; Yang, C.-C. Possible DNA Viral Factors of Human Breast Cancer. Cancers 2010, 2, 498-512.

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