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Cancers 2010, 2(2), 1125-1154; doi:10.3390/cancers2021125
Review

Markers for Detection of Prostate Cancer

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Received: 22 March 2010 / Revised: 2 June 2010 / Accepted: 3 June 2010 / Published: 4 June 2010
(This article belongs to the Special Issue Biomarkers: Oncology Studies)
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Abstract

Early detection of prostate cancer is problematic, not just because of uncertainly whether a diagnosis will benefit an individual patient, but also as a result of the imprecise and invasive nature of establishing a diagnosis by biopsy. Despite its low sensitivity and specificity for identifying patients harbouring prostate cancer, serum prostate specific antigen (PSA) has become established as the most reliable and widely-used diagnostic marker for this condition. In its wake, many other markers have been described and evaluated. This review focuses on the supporting evidence for the most prominent of these for detection and also for predicting outcome in prostate cancer.
Keywords: prostate cancer; biomarker; detection prostate cancer; biomarker; detection
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Clarke, R.A.; Schirra, H.J.; Catto, J.W.; Lavin, M.F.; Gardiner, R.A. Markers for Detection of Prostate Cancer. Cancers 2010, 2, 1125-1154.

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