Next Article in Journal
The Connection between the Presence of Melanoma and Changes in Fibre Diffraction Patterns
Next Article in Special Issue
Inflammatory Genetic Markers of Prostate Cancer Risk
Previous Article in Journal
Serum Tumor Markers in Pancreatic Cancer—Recent Discoveries
Previous Article in Special Issue
Reinventing Diagnostics for Personalized Therapy in Oncology
Cancers 2010, 2(2), 1125-1154; doi:10.3390/cancers2021125

Markers for Detection of Prostate Cancer

1 Prostate Cancer Institute, Cancer Care Centre, St George Hospital Clinical School of Medicine, University of New South Wales, Kogarah, NSW 2217, Australia 2 School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane QLD, 4072, Australia 3 Academic Urology Unit and Institute for Cancer Studies, University of Sheffield, Royal Hallamshire Hospital, Sheffield S10 2JF, UK 4 Queensland Institute of Medical Research, Radiation Biology and Oncology, Brisbane, QLD 4029, Australia 5 University of Queensland Centre for Clinical Research, Brisbane, Australia
* Author to whom correspondence should be addressed.
Received: 22 March 2010 / Revised: 2 June 2010 / Accepted: 3 June 2010 / Published: 4 June 2010
(This article belongs to the Special Issue Biomarkers: Oncology Studies)
View Full-Text   |   Download PDF [958 KB, uploaded 4 June 2010]   |   Browse Figures


Early detection of prostate cancer is problematic, not just because of uncertainly whether a diagnosis will benefit an individual patient, but also as a result of the imprecise and invasive nature of establishing a diagnosis by biopsy. Despite its low sensitivity and specificity for identifying patients harbouring prostate cancer, serum prostate specific antigen (PSA) has become established as the most reliable and widely-used diagnostic marker for this condition. In its wake, many other markers have been described and evaluated. This review focuses on the supporting evidence for the most prominent of these for detection and also for predicting outcome in prostate cancer.
Keywords: prostate cancer; biomarker; detection prostate cancer; biomarker; detection
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Share & Cite This Article

Further Mendeley | CiteULike
Export to BibTeX |
MDPI and ACS Style

Clarke, R.A.; Schirra, H.J.; Catto, J.W.; Lavin, M.F.; Gardiner, R.A. Markers for Detection of Prostate Cancer. Cancers 2010, 2, 1125-1154.

View more citation formats

Related Articles

Article Metrics

For more information on the journal, click here


Cited By

[Return to top]
Cancers EISSN 2072-6694 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert