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Wnt and Related Signaling Pathways in Melanomagenesis
Cancers 2010, 2(2), 1155-1165; doi:10.3390/cancers2021155

The Connection between the Presence of Melanoma and Changes in Fibre Diffraction Patterns

1,*  and 2
1 Research School of Chemistry, Australian National University, Canberra ACT 0200, Australia 2 Australian Synchrotron, 800 Blackburn Rd Clayton, VIC 3168, Australia
* Author to whom correspondence should be addressed.
Received: 5 May 2010 / Revised: 3 June 2010 / Accepted: 4 June 2010 / Published: 4 June 2010
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An accurate diagnosis of melanomas at an early stage correlates directly with a better prognosis. However the incidence of melanoma is still increasing along with the number of related deaths. Melanoma cells grow extremely fast, with the result that many patients present after metastasis has occurred, too late for effective treatment. This paper describes the changes in the fibre diffraction patterns of skin that indicate the presence of a melanoma. Identification of these changes would provide an alternative early low-cost, reliable diagnostic test which could be conducted on a regular basis in local radiology facilities using rotating anode X-ray generators or as a mass screening test using suitable small angle x-ray beam-lines at synchrotrons.
Keywords: melanoma; diagnosis; x-ray diffraction; skin melanoma; diagnosis; x-ray diffraction; skin
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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James, V.J.; Kirby, N. The Connection between the Presence of Melanoma and Changes in Fibre Diffraction Patterns. Cancers 2010, 2, 1155-1165.

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