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Micromachines 2017, 8(5), 144;

Rapid Fabrication of Disposable Micromixing Arrays Using Xurography and Laser Ablation

Tecnológico de Monterrey, Eugenio Garza Sada 2501 Sur, 64849 Monterrey, NL, Mexico
Author to whom correspondence should be addressed.
Academic Editors: Guido Tosello, Hans Nørgaard Hansen and Nam-Trung Nguyen
Received: 28 February 2017 / Revised: 26 April 2017 / Accepted: 28 April 2017 / Published: 4 May 2017
(This article belongs to the Special Issue Micro/Nano Manufacturing)
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We assessed xurography and laser ablation for the manufacture of passive micromixers arrays to explore the scalability of unconventional manufacture technologies that could be implemented under the restrictions of the Point of Care for developing countries. In this work, we present a novel split-and-recombine (SAR) array design adapted for interfacing standardized dispensing (handheld micropipette) and sampling (microplate reader) equipment. The design was patterned and sealed from A4 sized vinyl sheets (polyvinyl chloride), employing low-cost disposable materials. Manufacture was evaluated measuring the dimensional error with stereoscopic and confocal microscopy. The micromixing efficiency was estimated using a machine vision system for passive driven infusion provided by micropippetting samples of dye and water. It was possible to employ rapid fabrication based on xurography to develop a four channel asymmetric split-and-recombine (ASAR) micromixer with mixing efficiencies ranging from 43% to 65%. View Full-Text
Keywords: micromixing; split and recombine; rapid manufacture; xurography; laser ablation micromixing; split and recombine; rapid manufacture; xurography; laser ablation

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Supplementary materials

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  • Externally hosted supplementary file 1
    Description: Testing of a micromixer array fabricated using xurography and lamination. The proposed device was manufactured using low-cost materials and tested using a multi-channel micropipette as a proof-of-concept device of a design of a multichannel micromixer.

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Martínez-López, J.I.; Betancourt, H.; García-López, E.; Rodriguez, C.A.; Siller, H.R. Rapid Fabrication of Disposable Micromixing Arrays Using Xurography and Laser Ablation. Micromachines 2017, 8, 144.

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