Rapid Fabrication of Disposable Micromixing Arrays Using Xurography and Laser Ablation
AbstractWe assessed xurography and laser ablation for the manufacture of passive micromixers arrays to explore the scalability of unconventional manufacture technologies that could be implemented under the restrictions of the Point of Care for developing countries. In this work, we present a novel split-and-recombine (SAR) array design adapted for interfacing standardized dispensing (handheld micropipette) and sampling (microplate reader) equipment. The design was patterned and sealed from A4 sized vinyl sheets (polyvinyl chloride), employing low-cost disposable materials. Manufacture was evaluated measuring the dimensional error with stereoscopic and confocal microscopy. The micromixing efficiency was estimated using a machine vision system for passive driven infusion provided by micropippetting samples of dye and water. It was possible to employ rapid fabrication based on xurography to develop a four channel asymmetric split-and-recombine (ASAR) micromixer with mixing efficiencies ranging from 43% to 65%. View Full-Text
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Description: Testing of a micromixer array fabricated using xurography and lamination. The proposed device was manufactured using low-cost materials and tested using a multi-channel micropipette as a proof-of-concept device of a design of a multichannel micromixer.
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Martínez-López, J.I.; Betancourt, H.; García-López, E.; Rodriguez, C.A.; Siller, H.R. Rapid Fabrication of Disposable Micromixing Arrays Using Xurography and Laser Ablation. Micromachines 2017, 8, 144.
Martínez-López JI, Betancourt H, García-López E, Rodriguez CA, Siller HR. Rapid Fabrication of Disposable Micromixing Arrays Using Xurography and Laser Ablation. Micromachines. 2017; 8(5):144.Chicago/Turabian Style
Martínez-López, J. I.; Betancourt, H.A.; García-López, Erika; Rodriguez, Ciro A.; Siller, Hector R. 2017. "Rapid Fabrication of Disposable Micromixing Arrays Using Xurography and Laser Ablation." Micromachines 8, no. 5: 144.
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