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Micromachines 2017, 8(1), 9; doi:10.3390/mi8010009

Microfluidic Separation of a Soluble Substance Using Transverse Diffusion in a Layered Flow

1
School of Mechanical Engineering, Pusan National University, 2, Busandaehak-ro 63beon-gil, Geumjeong-gu, Busan 46241, Korea
2
Department of Polymer Science & Engineering, Pusan National University, 2, Busandaehak-ro 63beon-gil, Geumjeong-gu, Busan 46241, Korea
3
Department of Chemical & Biological Engineering, College of Engineering, Korea Univeristy, Anam-Dong, Seongbuk-Gu, Seoul 02841, Korea
4
Boditech Med Inc., 43, Geodudanji 1-gil, Dongnae-myeon, Chuncheon-si, Gang-won-do 24398, Korea
*
Author to whom correspondence should be addressed.
Academic Editors: Xunli Zhang and Dario Carugo
Received: 11 November 2016 / Revised: 23 December 2016 / Accepted: 26 December 2016 / Published: 29 December 2016
(This article belongs to the Special Issue Microfluidic Technologies for Drug Delivery)
View Full-Text   |   Download PDF [6354 KB, uploaded 29 December 2016]   |  

Abstract

This paper presents a practical flow-through method to separate anisole and ethyl phenylacetate, respectively, from a polystyrene mixture. The microfluidic separation uses different diffusive dynamics of the substances transverse to the lamination flow formed in a microchannel. The effect of inlet flow rates and ambient temperature on separation is examined. Additionally, the possibility of the separation of the light substance from the mixture with different molecular weight is shown numerically and experimentally. The separation efficiency is explained by the facts that the relaxation time depends on the inlet flow rate and that the diffusivity depends on the ambient temperature. This method can be applied to separate monomers from aggregates. View Full-Text
Keywords: transverse diffusion; layered flow; polymers; separation; microfluidic transverse diffusion; layered flow; polymers; separation; microfluidic
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MDPI and ACS Style

Nguyen, X.D.; Jeon, H.J.; Kim, H.Y.; Paik, H.J.; Huh, J.; Kim, H.H.; Go, J.S. Microfluidic Separation of a Soluble Substance Using Transverse Diffusion in a Layered Flow. Micromachines 2017, 8, 9.

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